Carolina B. López
@cblopezlab.bsky.social
Professor | the López lab studies how viruses interact with their host. We spend a lot of time thinking about non-standard viral genomes, henipaviruses and respiratory virus persistence. Lab website: www.lopezlab.org. Post do not represent my organization.
New paper by @italoacastro.bsky.social is out! In collaboration with the Kreisel Lab from the Department of surgery, we studied the impact of a lung viral infection in transplanted lungs...with some unexpected results! Take a look:
doi.org/10.1016/j.aj...
doi.org/10.1016/j.aj...
Redirecting
doi.org
September 16, 2025 at 2:22 PM
New paper by @italoacastro.bsky.social is out! In collaboration with the Kreisel Lab from the Department of surgery, we studied the impact of a lung viral infection in transplanted lungs...with some unexpected results! Take a look:
doi.org/10.1016/j.aj...
doi.org/10.1016/j.aj...
Reposted by Carolina B. López
As always, Ted Chiang is great in this interview.
cdh.princeton.edu/blog/2025/08...
cdh.princeton.edu/blog/2025/08...
August 14, 2025 at 1:24 AM
As always, Ted Chiang is great in this interview.
cdh.princeton.edu/blog/2025/08...
cdh.princeton.edu/blog/2025/08...
Congratulations to SB Pye and team for validating several paramyxovirus copyback genomes by direct RNA-Seq (no PCR involved). Specially cool are species formed between nucleotide 1 of the genome and a sequence close to the trailer..these are real products! journals.asm.org/doi/10.1128/...
Validation of diverse and previously untraceable Sendai virus copyback viral genomes by direct RNA sequencing | Journal of Virology
Most viruses of the order Mononegavirales have been demonstrated to naturally generate
copyback viral genomes. These genomes are critical determinants of infection outcomes;
they interfere with standa...
journals.asm.org
July 31, 2025 at 9:43 PM
Congratulations to SB Pye and team for validating several paramyxovirus copyback genomes by direct RNA-Seq (no PCR involved). Specially cool are species formed between nucleotide 1 of the genome and a sequence close to the trailer..these are real products! journals.asm.org/doi/10.1128/...
Reposted by Carolina B. López
The Sengupta lab is seeking research technicians to join its team. Ideal candidates must possess a passion for research and exceptional communication skills. Both early-career and experienced candidates are welcome. Email SenguptaS@chop.edu with CV and letter of interest with goals and expectations.
May 20, 2025 at 2:22 AM
The Sengupta lab is seeking research technicians to join its team. Ideal candidates must possess a passion for research and exceptional communication skills. Both early-career and experienced candidates are welcome. Email SenguptaS@chop.edu with CV and letter of interest with goals and expectations.
Reposted by Carolina B. López
Now you see me, now you don’t: What and how viral RNAs are detected by cytoplasmic pattern-recognition receptors
Now you see me, now you don’t: What and how viral RNAs are detected by cytoplasmic pattern-recognition receptors
In a recent issue of Molecular Cell, Genoyer et al. show that during West Nile virus infection, escaped, cytoplasmic, anti-genomic negative-sense viral RNA triggers an antiviral response via RIG-I activation. Flaviviruses typically hide −vRNA in replication compartments to avoid detection, but some −vRNA leaks, possibly aided by viral capsid proteins.
dlvr.it
April 18, 2025 at 11:33 AM
Now you see me, now you don’t: What and how viral RNAs are detected by cytoplasmic pattern-recognition receptors
Vergüenza ajena…que horror tanta ignorancia en este país que se supone “líder”
NIH to ax grants on vaccine hesitancy, mRNA vaccines. www.science.org/content/arti...
NIH to ax grants on vaccine hesitancy, mRNA vaccines
Move reflects vaccine skepticism of health secretary Robert F. Kennedy Jr.
www.science.org
March 11, 2025 at 3:25 AM
Vergüenza ajena…que horror tanta ignorancia en este país que se supone “líder”
Reposted by Carolina B. López
With this kind of people, bending over won’t help. Also, this IS the time to stand up for principles, particularly academic freedom, and… free speech. theintercept.com/2025/03/08/c...
Columbia Bent Over Backward to Appease Right-Wing, Pro-Israel Attacks — And Trump Still Cut Federal Funding
Columbia bent over backward to appease right-wing, pro-Israel attacks on Gaza protesters — and Trump still cut the school’s federal funding.
theintercept.com
March 10, 2025 at 12:05 AM
With this kind of people, bending over won’t help. Also, this IS the time to stand up for principles, particularly academic freedom, and… free speech. theintercept.com/2025/03/08/c...
Pretty nice turnout at Jefferson City, MO’s capitol for #StandUpforScience today given how far it is from the closest large cities. Thanks to the organizers and to all those who drove 2h to make it there!
March 8, 2025 at 1:01 AM
Pretty nice turnout at Jefferson City, MO’s capitol for #StandUpforScience today given how far it is from the closest large cities. Thanks to the organizers and to all those who drove 2h to make it there!
Reposted by Carolina B. López
Friends, we need 50 subscribers to our YouTube channel to be able to live stream today’s Birmingham Stand Up For Science march! Anyone willing to subscribe is greatly appreciated!
youtube.com/@standupfors...
youtube.com/@standupfors...
Stand Up for Science Alabama
youtube.com
March 7, 2025 at 3:54 PM
Friends, we need 50 subscribers to our YouTube channel to be able to live stream today’s Birmingham Stand Up For Science march! Anyone willing to subscribe is greatly appreciated!
youtube.com/@standupfors...
youtube.com/@standupfors...
Reposted by Carolina B. López
SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING!
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
March 6, 2025 at 7:14 PM
SO MANY STAND UP FOR SCIENCE EVENTS TO CHOOSE FROM—153 and COUNTING!
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
To get more information on our local events and to register your own, head to www.standupforscience2025.org/local-event-information/ ☀️⬇️🌎
Reposted by Carolina B. López
Our colleges & universities should encourage, not suppress, open & vigorous dialogue & debate about even the most deeply held beliefs.
Trump’s threats against student protesters are antithetical to the mission of higher education.
We strongly condemn them.
www.aaup.org/news/threats...
Trump’s threats against student protesters are antithetical to the mission of higher education.
We strongly condemn them.
www.aaup.org/news/threats...
Threats to Student Protest Are Antithetical to the Mission of Higher Education
The AAUP defends the right to free speech and peaceful protest on college and university campuses, a time-honored tradition protected by the First Amendment of the United States Constitution. Donald T...
www.aaup.org
March 5, 2025 at 6:09 PM
Our colleges & universities should encourage, not suppress, open & vigorous dialogue & debate about even the most deeply held beliefs.
Trump’s threats against student protesters are antithetical to the mission of higher education.
We strongly condemn them.
www.aaup.org/news/threats...
Trump’s threats against student protesters are antithetical to the mission of higher education.
We strongly condemn them.
www.aaup.org/news/threats...
Reposted by Carolina B. López
On Friday, we Stand Up for Science in locations Nationwide (& internationally!) to support science as a public good that benefits everyone.
Join us! Visit www.standupforscience2025.org for more information & other ways to get involved ☀️
Join us! Visit www.standupforscience2025.org for more information & other ways to get involved ☀️
March 4, 2025 at 12:36 PM
On Friday, we Stand Up for Science in locations Nationwide (& internationally!) to support science as a public good that benefits everyone.
Join us! Visit www.standupforscience2025.org for more information & other ways to get involved ☀️
Join us! Visit www.standupforscience2025.org for more information & other ways to get involved ☀️
Reposted by Carolina B. López
For the sake of humanity, it's time to get out there and Stand Up For Science!! Spread the word!
March 4, 2025 at 4:07 AM
For the sake of humanity, it's time to get out there and Stand Up For Science!! Spread the word!
Reposted by Carolina B. López
I got laid off today, with the rest of 18F.
18F was an elite federal software shop. We made gov't websites work better, more efficiently for the American people. We saved taxpayers from getting screwed over by contractors. And were fired for it.
We made this website to tell our story:
18f.org
18F was an elite federal software shop. We made gov't websites work better, more efficiently for the American people. We saved taxpayers from getting screwed over by contractors. And were fired for it.
We made this website to tell our story:
18f.org
We're not done yet | 18F
18f.org
March 1, 2025 at 10:38 PM
I got laid off today, with the rest of 18F.
18F was an elite federal software shop. We made gov't websites work better, more efficiently for the American people. We saved taxpayers from getting screwed over by contractors. And were fired for it.
We made this website to tell our story:
18f.org
18F was an elite federal software shop. We made gov't websites work better, more efficiently for the American people. We saved taxpayers from getting screwed over by contractors. And were fired for it.
We made this website to tell our story:
18f.org
Reposted by Carolina B. López
Rubella is a major cause of birth abnormalities if a pregnant woman gets exposed. That’s why we vaccinate against it. What about all those worries for unborn babies now???
February 28, 2025 at 9:11 PM
Rubella is a major cause of birth abnormalities if a pregnant woman gets exposed. That’s why we vaccinate against it. What about all those worries for unborn babies now???
Reposted by Carolina B. López
ATTENTION
The Washington Post is collecting data about funding issues. Please consider contributing.
thewashingtonpost.formstack.com/forms/scient...
The Washington Post is collecting data about funding issues. Please consider contributing.
thewashingtonpost.formstack.com/forms/scient...
Are you a scientist who has lost funding or grants in recent weeks? - Formstack
thewashingtonpost.formstack.com
February 26, 2025 at 6:19 PM
ATTENTION
The Washington Post is collecting data about funding issues. Please consider contributing.
thewashingtonpost.formstack.com/forms/scient...
The Washington Post is collecting data about funding issues. Please consider contributing.
thewashingtonpost.formstack.com/forms/scient...
Reposted by Carolina B. López
Very grateful to our @scripps.edu President/CEO Pete Schultz, for this OpEd in @sandiegouniontribune.com on the key importance of research institutions in U.S. biomedical science and how federal support is critical to fuel new discoveries and medicines.
www.sandiegouniontribune.com/2025/02/25/o...
www.sandiegouniontribune.com/2025/02/25/o...
Opinion: Science funding cuts are based on flawed logic. Here’s the truth.
Earlier this month, the National Institutes of Health issued supplemental guidance indicating it would immediately impose a 15% cap on indirect costs for research grants, an unprecedented and abrup…
www.sandiegouniontribune.com
February 26, 2025 at 2:21 AM
Very grateful to our @scripps.edu President/CEO Pete Schultz, for this OpEd in @sandiegouniontribune.com on the key importance of research institutions in U.S. biomedical science and how federal support is critical to fuel new discoveries and medicines.
www.sandiegouniontribune.com/2025/02/25/o...
www.sandiegouniontribune.com/2025/02/25/o...
Reposted by Carolina B. López
Reposted by Carolina B. López
Some good-ish news from NIH
“Federal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again”
As far as I know, the timing for this is not clear, but I will be checking the Federal Register.
“Federal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again”
As far as I know, the timing for this is not clear, but I will be checking the Federal Register.
a man in a red suit and tie is holding a piece of paper that says breaking news on it
ALT: a man in a red suit and tie is holding a piece of paper that says breaking news on it
media.tenor.com
February 24, 2025 at 4:38 PM
Some good-ish news from NIH
“Federal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again”
As far as I know, the timing for this is not clear, but I will be checking the Federal Register.
“Federal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again”
As far as I know, the timing for this is not clear, but I will be checking the Federal Register.
www.aei.org
February 23, 2025 at 4:18 AM
Reposted by Carolina B. López
A US Senator Joins the Fray. Thank you
@murray.senate.gov ! More of this, please!
www.murray.senate.gov/senator-murr...
@murray.senate.gov ! More of this, please!
www.murray.senate.gov/senator-murr...
Senator Murray Blasts Trump & Elon for Illegally Paralyzing Lifesaving Research Again, Threatening to Extinguish Ongoing and Groundbreaking Work - Senator Patty Murray
ICYMI: Murray Blasts Trump and Musk Decimating HHS, Risking Americans’ Health and Livelihoods Washington, D.C. — U.S. Senator Patty Murray (D-WA), Vice Chair of the Senate Appropriations Committee and...
www.murray.senate.gov
February 22, 2025 at 12:17 AM
A US Senator Joins the Fray. Thank you
@murray.senate.gov ! More of this, please!
www.murray.senate.gov/senator-murr...
@murray.senate.gov ! More of this, please!
www.murray.senate.gov/senator-murr...
This list with sources telling the reality of what is going on should be spread widely. Thanks for putting it together.
Sources
NIH grants still paused
archive.ph/2025.02.20-2...
NSF cuts (not primary source)
nanoscale.blogspot.com/2025/02/the-...
NIH study sections paused
www.thetransmitter.org/funding/fede...
biomed grad school amissions paused
www.statnews.com/2025/02/19/t...
NIH grants still paused
archive.ph/2025.02.20-2...
NSF cuts (not primary source)
nanoscale.blogspot.com/2025/02/the-...
NIH study sections paused
www.thetransmitter.org/funding/fede...
biomed grad school amissions paused
www.statnews.com/2025/02/19/t...
archive.ph
February 21, 2025 at 2:22 PM
This list with sources telling the reality of what is going on should be spread widely. Thanks for putting it together.
Reposted by Carolina B. López
No! Only study sections already announced in the federal register have resumed. Nothing has been posted by the NIH to the federal register since Jan 21.
I am finding it wild how many professors don't know this. Please spread this info to your Universities!
I am finding it wild how many professors don't know this. Please spread this info to your Universities!
February 17, 2025 at 3:39 PM
No! Only study sections already announced in the federal register have resumed. Nothing has been posted by the NIH to the federal register since Jan 21.
I am finding it wild how many professors don't know this. Please spread this info to your Universities!
I am finding it wild how many professors don't know this. Please spread this info to your Universities!
Gut-wrenching and perfectly describing the fear and impotence that many in the scientific community are experiencing today
This is gut-wrenching 😭😱https://www.bmj.com/content/388/bmj.r294
Anger, despair, and defiance from a voice within the US federal research system
People around the world are watching with disbelief as the new US government closes down its aid programme, withdraws from the World Health Organization (WHO) and the Paris agreement on climate change...
www.bmj.com
February 16, 2025 at 6:08 PM
Gut-wrenching and perfectly describing the fear and impotence that many in the scientific community are experiencing today
First paper of 2025! Postdoc Yanling Yang shows that SLC35A2 modulates paramyxovirus fusion events during infection | PLOS Pathogens journals.plos.org/plospathogen...
SLC35A2 modulates paramyxovirus fusion events during infection
Author summary Paramyxovirus entry, the first step in establishing an infection, involves two key processes: attachment and virus-cell fusion. Paramyxoviruses use their attachment protein to bind to s...
journals.plos.org
January 13, 2025 at 3:42 AM
First paper of 2025! Postdoc Yanling Yang shows that SLC35A2 modulates paramyxovirus fusion events during infection | PLOS Pathogens journals.plos.org/plospathogen...