Centre for Integrative Biology
@cbitoulouse.bsky.social
Reposted by Centre for Integrative Biology
Mechanical forces shape the developing brain 🧠💥 Compression from high cell density doesn’t just squeeze cells - it compromises mitotic fidelity! New preprint on how mechanics impact neural development from Veronique Marthiens & co-authors @institutcurie.bsky.social @cbitoulouse.bsky.social
🧠🔧👇
🧠🔧👇
Brain biomechanics governs mitotic fidelity of embryonic neural progenitors https://www.biorxiv.org/content/10.1101/2025.07.31.667957v1
August 1, 2025 at 1:32 PM
Mechanical forces shape the developing brain 🧠💥 Compression from high cell density doesn’t just squeeze cells - it compromises mitotic fidelity! New preprint on how mechanics impact neural development from Veronique Marthiens & co-authors @institutcurie.bsky.social @cbitoulouse.bsky.social
🧠🔧👇
🧠🔧👇
Reposted by Centre for Integrative Biology
Pleased to see this study out, combining experimental work from our lab at the @cbitoulouse.bsky.social, in particular by @nathaliebastie.bsky.social and @beckof.bsky.social, and from Laura Chaptal and @alengronne.bsky.social at IGH Montpellier
@cnrs.fr @cnrsbiologie.bsky.social
Congrats to all!
@cnrs.fr @cnrsbiologie.bsky.social
Congrats to all!
RNA Pol II-based regulations of chromosome folding
How transcription and cohesin complexes interact to regulate 3D genome organization
remains unclear. Chapard et al. dissect their respective contributions and their interplay
in shaping the genome arc...
www.cell.com
August 9, 2025 at 10:47 AM
Pleased to see this study out, combining experimental work from our lab at the @cbitoulouse.bsky.social, in particular by @nathaliebastie.bsky.social and @beckof.bsky.social, and from Laura Chaptal and @alengronne.bsky.social at IGH Montpellier
@cnrs.fr @cnrsbiologie.bsky.social
Congrats to all!
@cnrs.fr @cnrsbiologie.bsky.social
Congrats to all!
Reposted by Centre for Integrative Biology
#ResultatScientifique🔎| HP1, une protéine architecte déchue au cours de l’évolution
🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Fabian Erdel
📕 @narjournal.bsky.social | buff.ly/aimHSLW
buff.ly/1Bc1GQt
🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Fabian Erdel
📕 @narjournal.bsky.social | buff.ly/aimHSLW
buff.ly/1Bc1GQt
HP1, une protéine architecte déchue au cours de l’évolution
Dans un article publié dans la revue Nature Communications, des scientifiques ont étudié une protéine, appelée HP1, q
buff.ly
August 21, 2025 at 3:03 PM
#ResultatScientifique🔎| HP1, une protéine architecte déchue au cours de l’évolution
🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Fabian Erdel
📕 @narjournal.bsky.social | buff.ly/aimHSLW
buff.ly/1Bc1GQt
🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Fabian Erdel
📕 @narjournal.bsky.social | buff.ly/aimHSLW
buff.ly/1Bc1GQt
Reposted by Centre for Integrative Biology
#ResultatScientifique🔎| Le stress aide les poissons à renforcer leur intelligence collective et à s’adapter plus vite aux changements 🐟
🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Guy Theraulaz et Clément Sire
📕 @prxlife.bsky.social | buff.ly/m9Anxxe
🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Guy Theraulaz et Clément Sire
📕 @prxlife.bsky.social | buff.ly/m9Anxxe
September 5, 2025 at 8:30 AM
#ResultatScientifique🔎| Le stress aide les poissons à renforcer leur intelligence collective et à s’adapter plus vite aux changements 🐟
🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Guy Theraulaz et Clément Sire
📕 @prxlife.bsky.social | buff.ly/m9Anxxe
🤝 @cnrs.fr @cbitoulouse.bsky.social
✍️ Guy Theraulaz et Clément Sire
📕 @prxlife.bsky.social | buff.ly/m9Anxxe
Reposted by Centre for Integrative Biology
Check out @julielebris.bsky.social’s thread on our latest manuscript describing phenotypic heterogeneity in capsule production in Klebsiella & Acinetobacter @klebclub.bsky.social
This work started when I was still in @pasteur.fr & got finished in @cbitoulouse.bsky.social
#microsky #phagesky
This work started when I was still in @pasteur.fr & got finished in @cbitoulouse.bsky.social
#microsky #phagesky
Delighted to share our recently published work!
Ever wondered how Klebsiella (and others) deals with capsule production’s costs ?
The paper: journals.asm.org/doi/10.1128/...
Thread👇
Ever wondered how Klebsiella (and others) deals with capsule production’s costs ?
The paper: journals.asm.org/doi/10.1128/...
Thread👇
Phenotypic heterogeneity of capsule production across opportunistic pathogens | mBio
The polysaccharidic capsule is present in ~50% of species across the bacterial phylogeny, including all ESKAPE microorganisms, the six most significant multidrug-resistant (MDR) nosocomial pathogens. It is also an important virulence factor and a major ...
journals.asm.org
September 9, 2025 at 5:11 AM
Check out @julielebris.bsky.social’s thread on our latest manuscript describing phenotypic heterogeneity in capsule production in Klebsiella & Acinetobacter @klebclub.bsky.social
This work started when I was still in @pasteur.fr & got finished in @cbitoulouse.bsky.social
#microsky #phagesky
This work started when I was still in @pasteur.fr & got finished in @cbitoulouse.bsky.social
#microsky #phagesky
Reposted by Centre for Integrative Biology
📢 J-15 avant la fin de notre appel à projets de recherche sur Alzheimer 🧠
🔬Postuler ici : alzprojects.org/register?vie...
@unistra.fr
@inp-marseille.bsky.social
@cbitoulouse.bsky.social
@cbsmontpellier.bsky.social
@neuropresage.bsky.social
@urc-psl.bsky.social
@institutducerveau.bsky.social
🔬Postuler ici : alzprojects.org/register?vie...
@unistra.fr
@inp-marseille.bsky.social
@cbitoulouse.bsky.social
@cbsmontpellier.bsky.social
@neuropresage.bsky.social
@urc-psl.bsky.social
@institutducerveau.bsky.social
September 15, 2025 at 7:36 AM
📢 J-15 avant la fin de notre appel à projets de recherche sur Alzheimer 🧠
🔬Postuler ici : alzprojects.org/register?vie...
@unistra.fr
@inp-marseille.bsky.social
@cbitoulouse.bsky.social
@cbsmontpellier.bsky.social
@neuropresage.bsky.social
@urc-psl.bsky.social
@institutducerveau.bsky.social
🔬Postuler ici : alzprojects.org/register?vie...
@unistra.fr
@inp-marseille.bsky.social
@cbitoulouse.bsky.social
@cbsmontpellier.bsky.social
@neuropresage.bsky.social
@urc-psl.bsky.social
@institutducerveau.bsky.social
Reposted by Centre for Integrative Biology
Amazing work by Vishnu & the MechanoGut team! 💩⚙️🛠️ Huge thanks to @cbitoulouse.bsky.social imaging & animal facilities, our dear colleagues and collaborators, and funders @cnrs.fr ATIP-Avenir, ED-BSB, @frm-officiel.bsky.social
#Mechanobiology #GutBarrier #EpithelialBiology #CellAdhesion
#Mechanobiology #GutBarrier #EpithelialBiology #CellAdhesion
October 8, 2025 at 10:17 PM
Amazing work by Vishnu & the MechanoGut team! 💩⚙️🛠️ Huge thanks to @cbitoulouse.bsky.social imaging & animal facilities, our dear colleagues and collaborators, and funders @cnrs.fr ATIP-Avenir, ED-BSB, @frm-officiel.bsky.social
#Mechanobiology #GutBarrier #EpithelialBiology #CellAdhesion
#Mechanobiology #GutBarrier #EpithelialBiology #CellAdhesion
Reposted by Centre for Integrative Biology
Rejoignez-nous le 13 novembre 2025 !✨
Inscription sur notre site internet: scienc-e-s-2025.sciencesconf.org
Avec le support de la @sfr-b2s.bsky.social , le pôle égalité du @cbitoulouse.bsky.social , le Toulouse Mind and Brain Institute et @utoulouse.bsky.social
Inscription sur notre site internet: scienc-e-s-2025.sciencesconf.org
Avec le support de la @sfr-b2s.bsky.social , le pôle égalité du @cbitoulouse.bsky.social , le Toulouse Mind and Brain Institute et @utoulouse.bsky.social
October 9, 2025 at 1:30 PM
Rejoignez-nous le 13 novembre 2025 !✨
Inscription sur notre site internet: scienc-e-s-2025.sciencesconf.org
Avec le support de la @sfr-b2s.bsky.social , le pôle égalité du @cbitoulouse.bsky.social , le Toulouse Mind and Brain Institute et @utoulouse.bsky.social
Inscription sur notre site internet: scienc-e-s-2025.sciencesconf.org
Avec le support de la @sfr-b2s.bsky.social , le pôle égalité du @cbitoulouse.bsky.social , le Toulouse Mind and Brain Institute et @utoulouse.bsky.social
Reposted by Centre for Integrative Biology
Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
October 13, 2025 at 4:26 PM
Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
Reposted by Centre for Integrative Biology
5/🧵
This work is the result of a great collaboration between labs at
@ipparis.bsky.social , @ifremer.bsky.social , @cbitoulouse.bsky.social and @pasteur.fr
Many thanks to all colleagues involved 🙌
This work is the result of a great collaboration between labs at
@ipparis.bsky.social , @ifremer.bsky.social , @cbitoulouse.bsky.social and @pasteur.fr
Many thanks to all colleagues involved 🙌
October 13, 2025 at 4:30 PM
5/🧵
This work is the result of a great collaboration between labs at
@ipparis.bsky.social , @ifremer.bsky.social , @cbitoulouse.bsky.social and @pasteur.fr
Many thanks to all colleagues involved 🙌
This work is the result of a great collaboration between labs at
@ipparis.bsky.social , @ifremer.bsky.social , @cbitoulouse.bsky.social and @pasteur.fr
Many thanks to all colleagues involved 🙌
Reposted by Centre for Integrative Biology
🧠 Le projet de Claire Rampon @cbitoulouse.bsky.social explore la mitophagie, (élimination ciblée des mitochondries abîmées).
🔬 Objectif: mieux comprendre la mitophagie et si son dysfonctionnement pourrait contribuer à la maladie d’Alzheimer.
En savoir plus : alzheimer-recherche.org/projets/proj...
🔬 Objectif: mieux comprendre la mitophagie et si son dysfonctionnement pourrait contribuer à la maladie d’Alzheimer.
En savoir plus : alzheimer-recherche.org/projets/proj...
June 16, 2025 at 6:15 AM
🧠 Le projet de Claire Rampon @cbitoulouse.bsky.social explore la mitophagie, (élimination ciblée des mitochondries abîmées).
🔬 Objectif: mieux comprendre la mitophagie et si son dysfonctionnement pourrait contribuer à la maladie d’Alzheimer.
En savoir plus : alzheimer-recherche.org/projets/proj...
🔬 Objectif: mieux comprendre la mitophagie et si son dysfonctionnement pourrait contribuer à la maladie d’Alzheimer.
En savoir plus : alzheimer-recherche.org/projets/proj...
Reposted by Centre for Integrative Biology
Quand l’ARN s’invite dans la réparation de l’ADN ... 🧬
🤝 @lablegube.bsky.social @cbitoulouse.bsky.social
👉 Lire l'article dans @natcellbio.nature.com
buff.ly/CxP2P6N
buff.ly/PY2loYA
🤝 @lablegube.bsky.social @cbitoulouse.bsky.social
👉 Lire l'article dans @natcellbio.nature.com
buff.ly/CxP2P6N
buff.ly/PY2loYA
Quand l’ARN s’invite dans la réparation de l’ADN
Quand notre ADN se casse, nos cellules le réparent avec une haute précision.
www.insb.cnrs.fr
July 17, 2025 at 5:01 AM
Quand l’ARN s’invite dans la réparation de l’ADN ... 🧬
🤝 @lablegube.bsky.social @cbitoulouse.bsky.social
👉 Lire l'article dans @natcellbio.nature.com
buff.ly/CxP2P6N
buff.ly/PY2loYA
🤝 @lablegube.bsky.social @cbitoulouse.bsky.social
👉 Lire l'article dans @natcellbio.nature.com
buff.ly/CxP2P6N
buff.ly/PY2loYA
Reposted by Centre for Integrative Biology
Kicking off the #MIRA workshop in style with a fantastic keynote from Marie-Cécile Ploy on the global state of #AMR research, insightful and inspiring!
@ipbstoulouse.bsky.social @cbitoulouse.bsky.social
@ipbstoulouse.bsky.social @cbitoulouse.bsky.social
May 26, 2025 at 2:58 PM
Kicking off the #MIRA workshop in style with a fantastic keynote from Marie-Cécile Ploy on the global state of #AMR research, insightful and inspiring!
@ipbstoulouse.bsky.social @cbitoulouse.bsky.social
@ipbstoulouse.bsky.social @cbitoulouse.bsky.social
Reposted by Centre for Integrative Biology
Great talk today @cbitoulouse.bsky.social from @annechevallereau.bsky.social- on the importance of surface receptors in phage adsorption and of intracellular phage defense mechanisms - and the relative importance of each of them in shaping phage host range &productive phage infection 🦠
May 6, 2025 at 8:37 PM
Great talk today @cbitoulouse.bsky.social from @annechevallereau.bsky.social- on the importance of surface receptors in phage adsorption and of intracellular phage defense mechanisms - and the relative importance of each of them in shaping phage host range &productive phage infection 🦠
Reposted by Centre for Integrative Biology
🐜 How do ants navigate 100+ metres of forest with tiny, low-res eyes, and never get lost?
Antoine Wystrach @cbitoulouse.bsky.social dives into the genius of these insect navigators who mange to find their way without GPS or trails, just memory and vision.
More 👉 bit.ly/42AjG3S
#FrontierResearch
Antoine Wystrach @cbitoulouse.bsky.social dives into the genius of these insect navigators who mange to find their way without GPS or trails, just memory and vision.
More 👉 bit.ly/42AjG3S
#FrontierResearch
May 8, 2025 at 7:03 AM
🐜 How do ants navigate 100+ metres of forest with tiny, low-res eyes, and never get lost?
Antoine Wystrach @cbitoulouse.bsky.social dives into the genius of these insect navigators who mange to find their way without GPS or trails, just memory and vision.
More 👉 bit.ly/42AjG3S
#FrontierResearch
Antoine Wystrach @cbitoulouse.bsky.social dives into the genius of these insect navigators who mange to find their way without GPS or trails, just memory and vision.
More 👉 bit.ly/42AjG3S
#FrontierResearch
Reposted by Centre for Integrative Biology
Is our gut epithelium a little cracked ? Turns out—yes🤯 , and especially around goblet cells! Check out the new preprint from our very talented neighbors @cbitoulouse.bsky.social👇
🥳 Thrilled to share our lab's first preprint, led by our talented postdoc Justine Creff! 👩🏻🔬 We tackled a fundamental question: how the epithelium withstands mechanical stress at the interface of cells with distinct geometries and mechanics, such as enterocytes (E) and goblet cells (G) (1/9)
April 7, 2025 at 7:18 AM
Is our gut epithelium a little cracked ? Turns out—yes🤯 , and especially around goblet cells! Check out the new preprint from our very talented neighbors @cbitoulouse.bsky.social👇
Reposted by Centre for Integrative Biology
Here our new preprint on the LPS holo-translocon doi.org/10.1101/2025... , collaboration with Yves Quentin @JulieMarcoux @fronzeslab.bsky.social @pstansfeld.bsky.social - @cbitoulouse.bsky.social
Structural Basis of Lipopolysaccharide Assembly by the Outer Membrane Translocon Holo-Complex
Lipopolysaccharide (LPS) assembly at the surfaces-exposed leaflet of the bacterial outer membrane (OM) is mediated by the OM LPS translocon. An essential transmembrane beta-barrel protein, LptD, and a...
doi.org
April 11, 2025 at 6:11 AM
Here our new preprint on the LPS holo-translocon doi.org/10.1101/2025... , collaboration with Yves Quentin @JulieMarcoux @fronzeslab.bsky.social @pstansfeld.bsky.social - @cbitoulouse.bsky.social
Reposted by Centre for Integrative Biology
Venez découvrir les intervenants du @cbitoulouse.bsky.social
🎉ÇA Y EST !!
Le programme #pint25 de presque toutes les villes est en ligne !!
À consulter ici 👉 pintofscience.fr 👈
🎫Vous avez deux semaines pour le découvrir tranquillement, les tickets seront en ligne lundi 14 avril !
👓🧠❤🔥Alors, quelle est votre soirée préférée
Le programme #pint25 de presque toutes les villes est en ligne !!
À consulter ici 👉 pintofscience.fr 👈
🎫Vous avez deux semaines pour le découvrir tranquillement, les tickets seront en ligne lundi 14 avril !
👓🧠❤🔥Alors, quelle est votre soirée préférée
March 31, 2025 at 12:46 PM
Venez découvrir les intervenants du @cbitoulouse.bsky.social
Reposted by Centre for Integrative Biology
Funded post-doc positions in our excellent neighboring lab in the South of France @cbitoulouse.bsky.social @sfbd.bsky.social
April 1, 2025 at 1:31 PM
Funded post-doc positions in our excellent neighboring lab in the South of France @cbitoulouse.bsky.social @sfbd.bsky.social
🐟 𝗔 𝗻𝗲𝘄 𝗲𝘂𝗿𝗼𝗽𝗲𝗮𝗻 𝗽𝗿𝗼𝗷𝗲𝗰𝘁 𝗹𝗮𝘂𝗻𝗰𝗵𝗲𝗱 𝗮𝘁 𝗖𝗥𝗖𝗔-𝗖𝗕𝗜 𝘁𝗼 𝘀𝘁𝘂𝗱𝘆 𝘇𝗲𝗯𝗿𝗮𝗳𝗶𝘀𝗵𝗲𝘀 𝗺𝗼𝘃𝗲𝗺𝗲𝗻𝘁𝘀 𝗳𝗼𝗿 𝗮𝗻 𝗮𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗼𝗻 𝗱𝗿𝗼𝗻𝗲𝘀 𝗺𝗼𝘁𝗶𝗼𝗻!
Dari Borisov Trendafilov is a new Marie Curie Postdoct co-supervised by Dr Guy Theraulaz, CNRS Research Director and Dr Gautier Hattenberger, prof at ENAC
#Toulouse @cnrs.fr
Dari Borisov Trendafilov is a new Marie Curie Postdoct co-supervised by Dr Guy Theraulaz, CNRS Research Director and Dr Gautier Hattenberger, prof at ENAC
#Toulouse @cnrs.fr
March 17, 2025 at 1:41 PM
Pour lancer la @semaineducerveau.bsky.social à #Toulouse : une conférence de M. Lihoreau, chercheur @cnrs.fr au CRCA-CBI, ce soir à 18h30 au Muséum
"A quoi pensent les abeilles ?" pour découvrir les capacités cognitives insoupçonnées de ces insectes au cerveau miniature.
"A quoi pensent les abeilles ?" pour découvrir les capacités cognitives insoupçonnées de ces insectes au cerveau miniature.
March 10, 2025 at 2:16 PM
Pour lancer la @semaineducerveau.bsky.social à #Toulouse : une conférence de M. Lihoreau, chercheur @cnrs.fr au CRCA-CBI, ce soir à 18h30 au Muséum
"A quoi pensent les abeilles ?" pour découvrir les capacités cognitives insoupçonnées de ces insectes au cerveau miniature.
"A quoi pensent les abeilles ?" pour découvrir les capacités cognitives insoupçonnées de ces insectes au cerveau miniature.
Reposted by Centre for Integrative Biology
Voici un starter pack pour suivre la recherche en France : instituts, laboratoires, universités et agences.
N'hésitez pas à proposer des comptes à ajouter !
go.bsky.app/JSXcYqn
N'hésitez pas à proposer des comptes à ajouter !
go.bsky.app/JSXcYqn
January 22, 2025 at 3:15 PM
Voici un starter pack pour suivre la recherche en France : instituts, laboratoires, universités et agences.
N'hésitez pas à proposer des comptes à ajouter !
go.bsky.app/JSXcYqn
N'hésitez pas à proposer des comptes à ajouter !
go.bsky.app/JSXcYqn