@categraca.bsky.social
Reposted
Beyond prostate cancer: Androgen receptor signaling plays a key role in multiple malignancies. Dotto & collegues explore AR’s context-dependent functions in cancer cells & the TME, and highlight AR-targeting cancer trials.
📖 👇
📖 👇
Androgen receptor signalling in non-prostatic malignancies: challenges and opportunities - Nature Reviews Cancer
go.nature.com
February 15, 2025 at 2:28 PM
Beyond prostate cancer: Androgen receptor signaling plays a key role in multiple malignancies. Dotto & collegues explore AR’s context-dependent functions in cancer cells & the TME, and highlight AR-targeting cancer trials.
📖 👇
📖 👇
Reposted
ID3 defines stem-like T cells with high developmental potential that sustain T cell responses to chronic infection and cancer
www.science.org/doi/10.1126/...
@sciimmunology.bsky.social
www.science.org/doi/10.1126/...
@sciimmunology.bsky.social
January 31, 2025 at 11:23 PM
ID3 defines stem-like T cells with high developmental potential that sustain T cell responses to chronic infection and cancer
www.science.org/doi/10.1126/...
@sciimmunology.bsky.social
www.science.org/doi/10.1126/...
@sciimmunology.bsky.social
Very happy to share our new work!
Excited for our lab's FIRST paper #ScienceImmunology! 🎉
Led by @categraca.bsky.social & Amania Sheikh, with amazing collabs from Axel Kallies, Dane Newman, & @rickyjohnstone.bsky.social
Huge thanks to reviewers & @claireolingy.bsky.social 🙌
#Tpex #onthescoreboard
www.science.org/doi/full/10....
Led by @categraca.bsky.social & Amania Sheikh, with amazing collabs from Axel Kallies, Dane Newman, & @rickyjohnstone.bsky.social
Huge thanks to reviewers & @claireolingy.bsky.social 🙌
#Tpex #onthescoreboard
www.science.org/doi/full/10....
Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression
ID3 defines stem-like T cells with high developmental potential that sustain T cell responses to chronic infection and cancer.
www.science.org
January 31, 2025 at 8:58 PM
Very happy to share our new work!
Reposted
Slow-motion videos reveal tree frogs making some of the most dramatic landings in nature.
Learn more: scim.ag/4gTAurn
Learn more: scim.ag/4gTAurn
January 15, 2025 at 7:49 PM
Slow-motion videos reveal tree frogs making some of the most dramatic landings in nature.
Learn more: scim.ag/4gTAurn
Learn more: scim.ag/4gTAurn
Reposted
Interested in how T cells are regulated in a tissue-specific manner? Karthik Varanasi’s exciting work shows Bile Acid synthesis impedes tumor-specific T cell responses during liver cancer @science.org Huge THANKS to all the amazing collaborators + @salkinstitute, SBP
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Bile acid synthesis impedes tumor-specific T cell responses during liver cancer
The metabolic landscape of cancer greatly influences antitumor immunity, yet it remains unclear how organ-specific metabolites in the tumor microenvironment influence immunosurveillance. We found that...
www.science.org
January 11, 2025 at 10:12 PM
Interested in how T cells are regulated in a tissue-specific manner? Karthik Varanasi’s exciting work shows Bile Acid synthesis impedes tumor-specific T cell responses during liver cancer @science.org Huge THANKS to all the amazing collaborators + @salkinstitute, SBP
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...