Ken Campbell
@cardiaccampbell.bsky.social
Director of Translational Research for Cardiovascular Medicine at the University of Kentucky
Pinned
American Heart Association Journals
www.ahajournals.org
On behalf of our team at @ukresearch.bsky.social, highlighting "Patients who donate biospecimens for research leave a valuable and underappreciated scientific legacy".
We can all remember that behind every data point is a person, a family, and a story.
www.ahajournals.org/eprint/8HECU...
We can all remember that behind every data point is a person, a family, and a story.
www.ahajournals.org/eprint/8HECU...
Reposted by Ken Campbell
We will soon be looking for a comp biologist or bioinformatician to work on a number of linked projects within the lab - main focus is on molecular control of muscle
Before the official advert is published, I’m hoping to spread the news to any talented near-finishing PhDs or keen postdocs!
Before the official advert is published, I’m hoping to spread the news to any talented near-finishing PhDs or keen postdocs!
October 29, 2025 at 7:59 AM
We will soon be looking for a comp biologist or bioinformatician to work on a number of linked projects within the lab - main focus is on molecular control of muscle
Before the official advert is published, I’m hoping to spread the news to any talented near-finishing PhDs or keen postdocs!
Before the official advert is published, I’m hoping to spread the news to any talented near-finishing PhDs or keen postdocs!
Lovely profile of Mindy Thompson, one of our lab's great alumni.
medicine.uky.edu/news/saying-...
medicine.uky.edu/news/saying-...
Saying yes to opportunity: How Mindy Thompson built a career at UK
medicine.uky.edu
October 27, 2025 at 11:14 PM
Lovely profile of Mindy Thompson, one of our lab's great alumni.
medicine.uky.edu/news/saying-...
medicine.uky.edu/news/saying-...
On behalf of our team at @ukresearch.bsky.social, highlighting "Patients who donate biospecimens for research leave a valuable and underappreciated scientific legacy".
We can all remember that behind every data point is a person, a family, and a story.
www.ahajournals.org/eprint/8HECU...
We can all remember that behind every data point is a person, a family, and a story.
www.ahajournals.org/eprint/8HECU...
American Heart Association Journals
www.ahajournals.org
October 9, 2025 at 11:51 AM
On behalf of our team at @ukresearch.bsky.social, highlighting "Patients who donate biospecimens for research leave a valuable and underappreciated scientific legacy".
We can all remember that behind every data point is a person, a family, and a story.
www.ahajournals.org/eprint/8HECU...
We can all remember that behind every data point is a person, a family, and a story.
www.ahajournals.org/eprint/8HECU...
Reposted by Ken Campbell
Congrats to new #NobelLaureates Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi for their discoveries of peripheral immune tolerance and T reg cells. Read more: https://ow.ly/aiHn50X74mS #NobelPrize #Physiology
October 6, 2025 at 4:02 PM
Congrats to new #NobelLaureates Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi for their discoveries of peripheral immune tolerance and T reg cells. Read more: https://ow.ly/aiHn50X74mS #NobelPrize #Physiology
Reposted by Ken Campbell
A recent article in Circulation Research highlights findings from the van Berlo research lab, indicating that the cytoskeletal protein Septin4 plays a role in the onset of cardiac fibrosis by modifying the function of calcineurin. Read the full article: buff.ly/EUNsdKG #UMNresearch #Cardiosky
October 6, 2025 at 6:00 PM
A recent article in Circulation Research highlights findings from the van Berlo research lab, indicating that the cytoskeletal protein Septin4 plays a role in the onset of cardiac fibrosis by modifying the function of calcineurin. Read the full article: buff.ly/EUNsdKG #UMNresearch #Cardiosky
Delighted to see myocardial samples donated by patients and organ donors at @ukresearch.bsky.social supporting another important publication. Thank you for the opportunity to contribute.
academic.oup.com/cardiovascre...
academic.oup.com/cardiovascre...
RRAD-reduction reveals efficacy of targeting L-type calcium channel regulation for treatment of heart failure
AbstractAims. Heart failure with reduced ejection fraction (HFrEF) is a major health problem. Increasing L-type calcium channel (LTCC) activity deteriorate
academic.oup.com
October 3, 2025 at 3:44 PM
Delighted to see myocardial samples donated by patients and organ donors at @ukresearch.bsky.social supporting another important publication. Thank you for the opportunity to contribute.
academic.oup.com/cardiovascre...
academic.oup.com/cardiovascre...
Reposted by Ken Campbell
Our department is recruiting a new tenure track Assistant/Associate Professor. Come join the #1 physiology department in the country and some awesome colleagues doing high impact science and training the next generation of scientists
jobs.sciencecareers.org/job/674815/a...
jobs.sciencecareers.org/job/674815/a...
Assistant/Associate Professor - Tenure Track - Physiology - University of Michigan, Ann Arbor job with University of Michigan Department of Molecular & Integrative Physiology | 674815
Tenure track assistant/associate professor in the Department of Molecular & Integrative Physiology at the University of Michigan Medical School.
jobs.sciencecareers.org
August 28, 2025 at 3:35 PM
Our department is recruiting a new tenure track Assistant/Associate Professor. Come join the #1 physiology department in the country and some awesome colleagues doing high impact science and training the next generation of scientists
jobs.sciencecareers.org/job/674815/a...
jobs.sciencecareers.org/job/674815/a...
Reposted by Ken Campbell
Please repost!
We have an open rank, tenure-line faculty position in biomechanics in the School of Kinesiology at the University of Michigan Ann Arbor. At U-M we have great colleagues, exceptional resources, and biomechanics can be found all across the campus. #BiomechSky
We have an open rank, tenure-line faculty position in biomechanics in the School of Kinesiology at the University of Michigan Ann Arbor. At U-M we have great colleagues, exceptional resources, and biomechanics can be found all across the campus. #BiomechSky
Tenure-track Faculty Position in Biomechanics (Open Rank), University of Michigan, Ann Arbor, MI, USA -
Biomch-L
The School of Kinesiology (http://kines.umich.edu) at the University of Michigan invites applications and nominations for a tenure-track faculty position at the level of Assistant Professor, Associate...
biomch-l.isbweb.org
August 28, 2025 at 9:44 PM
Please repost!
We have an open rank, tenure-line faculty position in biomechanics in the School of Kinesiology at the University of Michigan Ann Arbor. At U-M we have great colleagues, exceptional resources, and biomechanics can be found all across the campus. #BiomechSky
We have an open rank, tenure-line faculty position in biomechanics in the School of Kinesiology at the University of Michigan Ann Arbor. At U-M we have great colleagues, exceptional resources, and biomechanics can be found all across the campus. #BiomechSky
Reposted by Ken Campbell
#musclesyneRgies 1.2.5.9009 (development version)
How to install
𝚒𝚗𝚜𝚝𝚊𝚕𝚕.𝚙𝚊𝚌𝚔𝚊𝚐𝚎𝚜("𝚛𝚎𝚖𝚘𝚝𝚎𝚜")
𝚛𝚎𝚖𝚘𝚝𝚎𝚜::𝚒𝚗𝚜𝚝𝚊𝚕𝚕_𝚐𝚒𝚝𝚑𝚞𝚋("𝚊𝚕𝚎𝚜𝚊𝚗𝚝𝚞𝚣/𝚖𝚞𝚜𝚌𝚕𝚎𝚜𝚢𝚗𝚎𝚁𝚐𝚒𝚎𝚜")
Improved function CoA with non-duplicated angles and robust quadrant handling. Please update!
#rstats #opensource
github.com/alesantuz/mu...
How to install
𝚒𝚗𝚜𝚝𝚊𝚕𝚕.𝚙𝚊𝚌𝚔𝚊𝚐𝚎𝚜("𝚛𝚎𝚖𝚘𝚝𝚎𝚜")
𝚛𝚎𝚖𝚘𝚝𝚎𝚜::𝚒𝚗𝚜𝚝𝚊𝚕𝚕_𝚐𝚒𝚝𝚑𝚞𝚋("𝚊𝚕𝚎𝚜𝚊𝚗𝚝𝚞𝚣/𝚖𝚞𝚜𝚌𝚕𝚎𝚜𝚢𝚗𝚎𝚁𝚐𝚒𝚎𝚜")
Improved function CoA with non-duplicated angles and robust quadrant handling. Please update!
#rstats #opensource
github.com/alesantuz/mu...
August 26, 2025 at 1:18 PM
#musclesyneRgies 1.2.5.9009 (development version)
How to install
𝚒𝚗𝚜𝚝𝚊𝚕𝚕.𝚙𝚊𝚌𝚔𝚊𝚐𝚎𝚜("𝚛𝚎𝚖𝚘𝚝𝚎𝚜")
𝚛𝚎𝚖𝚘𝚝𝚎𝚜::𝚒𝚗𝚜𝚝𝚊𝚕𝚕_𝚐𝚒𝚝𝚑𝚞𝚋("𝚊𝚕𝚎𝚜𝚊𝚗𝚝𝚞𝚣/𝚖𝚞𝚜𝚌𝚕𝚎𝚜𝚢𝚗𝚎𝚁𝚐𝚒𝚎𝚜")
Improved function CoA with non-duplicated angles and robust quadrant handling. Please update!
#rstats #opensource
github.com/alesantuz/mu...
How to install
𝚒𝚗𝚜𝚝𝚊𝚕𝚕.𝚙𝚊𝚌𝚔𝚊𝚐𝚎𝚜("𝚛𝚎𝚖𝚘𝚝𝚎𝚜")
𝚛𝚎𝚖𝚘𝚝𝚎𝚜::𝚒𝚗𝚜𝚝𝚊𝚕𝚕_𝚐𝚒𝚝𝚑𝚞𝚋("𝚊𝚕𝚎𝚜𝚊𝚗𝚝𝚞𝚣/𝚖𝚞𝚜𝚌𝚕𝚎𝚜𝚢𝚗𝚎𝚁𝚐𝚒𝚎𝚜")
Improved function CoA with non-duplicated angles and robust quadrant handling. Please update!
#rstats #opensource
github.com/alesantuz/mu...
GelBox - reproducible analysis of gels and immunoblots
campbell-muscle-lab.github.io/GelBox/
pubmed.ncbi.nlm.nih.gov/39092999/
campbell-muscle-lab.github.io/GelBox/
pubmed.ncbi.nlm.nih.gov/39092999/
August 26, 2025 at 11:32 PM
GelBox - reproducible analysis of gels and immunoblots
campbell-muscle-lab.github.io/GelBox/
pubmed.ncbi.nlm.nih.gov/39092999/
campbell-muscle-lab.github.io/GelBox/
pubmed.ncbi.nlm.nih.gov/39092999/
Congrats to Brent Scott from the Greenberg lab for this new paper on danicamtiv's mechanism of action.
www.pnas.org/doi/10.1073/...
Excited to see our FiberSim code being put to such good use.
campbell-muscle-lab.github.io/FiberSim/
www.pnas.org/doi/10.1073/...
Excited to see our FiberSim code being put to such good use.
campbell-muscle-lab.github.io/FiberSim/
Danicamtiv reduces myosin’s working stroke but activates the thin filament by accelerating actomyosin attachment | PNAS
Heart failure is a leading cause of death worldwide, and even with current treatments,
the 5-y transplant-free survival rate is only ~50 to 70%. As...
www.pnas.org
August 20, 2025 at 8:25 PM
Congrats to Brent Scott from the Greenberg lab for this new paper on danicamtiv's mechanism of action.
www.pnas.org/doi/10.1073/...
Excited to see our FiberSim code being put to such good use.
campbell-muscle-lab.github.io/FiberSim/
www.pnas.org/doi/10.1073/...
Excited to see our FiberSim code being put to such good use.
campbell-muscle-lab.github.io/FiberSim/
Reposted by Ken Campbell
Can you really repair an engine while it's running? 👩🏽🔧
The heart can. 💪🏼🫀
Our latest @faseborg.bsky.social paper shows how the protein 'CapZ' helps heart muscle to keep running during exercise. ⛹🏼♀️🏊♂️
#Exercise #Heart #Muscle #BasicScience #Cardiology
faseb.onlinelibrary.wiley.com/doi/10.1096/...
The heart can. 💪🏼🫀
Our latest @faseborg.bsky.social paper shows how the protein 'CapZ' helps heart muscle to keep running during exercise. ⛹🏼♀️🏊♂️
#Exercise #Heart #Muscle #BasicScience #Cardiology
faseb.onlinelibrary.wiley.com/doi/10.1096/...
Cardiac CapZ Regulation During Acute Exercise in Female Mice
CapZ regulates actin addition at the barbed ends of sarcomeric actin. At rest, phosphorylated CapZIP slows addition, and dephosphorylated CapZIP promotes a wobble state to allow actin cycling. During...
faseb.onlinelibrary.wiley.com
August 20, 2025 at 3:48 PM
Can you really repair an engine while it's running? 👩🏽🔧
The heart can. 💪🏼🫀
Our latest @faseborg.bsky.social paper shows how the protein 'CapZ' helps heart muscle to keep running during exercise. ⛹🏼♀️🏊♂️
#Exercise #Heart #Muscle #BasicScience #Cardiology
faseb.onlinelibrary.wiley.com/doi/10.1096/...
The heart can. 💪🏼🫀
Our latest @faseborg.bsky.social paper shows how the protein 'CapZ' helps heart muscle to keep running during exercise. ⛹🏼♀️🏊♂️
#Exercise #Heart #Muscle #BasicScience #Cardiology
faseb.onlinelibrary.wiley.com/doi/10.1096/...
Reposted by Ken Campbell
Always exciting to see new HF agents in development! I enjoyed reading this interesting study using porcine model of HF with some promising outcomes for MiR-132. Available now in @escardio.bsky.social journal EHJ-IMP: academic.oup.com/ehjimp/artic...
MiR-132 inhibition improves myocardial strain in a large animal model of chronic left ventricular adverse remodelling
AbstractAims. Cardiac miR-132 has been proposed as a target for heart failure (HF) therapy. CDR132L, a rationally designed synthetic oligonucleotide inhibi
academic.oup.com
August 17, 2025 at 8:57 PM
Always exciting to see new HF agents in development! I enjoyed reading this interesting study using porcine model of HF with some promising outcomes for MiR-132. Available now in @escardio.bsky.social journal EHJ-IMP: academic.oup.com/ehjimp/artic...
Reposted by Ken Campbell
Very happy to have been awarded a NIRG from the MRC. Stay tuned for some exciting (I think, but being biased) postdoc positions within our lab!
Congratulations to Dr Robert Seaborne @kingscollegelondon.bsky.social who has been awarded a New Investigator Grant from the Medical Research Council (MRC), which will support his work on understanding the role of skeletal muscle in motor neurone disease.
Read more ➡️ www.kcl.ac.uk/news/dr-robe...
Read more ➡️ www.kcl.ac.uk/news/dr-robe...
August 13, 2025 at 3:05 PM
Very happy to have been awarded a NIRG from the MRC. Stay tuned for some exciting (I think, but being biased) postdoc positions within our lab!
Another great paper from Dan Beard's group at @umich.edu addressing measurements of the SRX / IHM / OFF state in myosin.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Kinetic Modeling of mant-ATP Turnover to Interpret the Biochemically Defined Myosin Super-Relaxed State
The fluorescent ATP analog mant-ATP has become a valuable tool for quantifying occupancy of the myosin super-relaxed (SRX) state, a biochemically inactive conformation of myosin in striated muscle. In...
www.biorxiv.org
August 11, 2025 at 7:52 PM
Another great paper from Dan Beard's group at @umich.edu addressing measurements of the SRX / IHM / OFF state in myosin.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Excited to be working with Jonathan Wenk (University of Kentucky) and Lik-Chuan Lee (Michigan State University) on computer modeling of cardiac fibrosis.
uknow.uky.edu/research/uk-...
uknow.uky.edu/research/uk-...
UK engineering researcher leads NSF‑funded initiative to model heart fibrosis with machine learning
Researchers in the Stanley and Karen Pigman College of Engineering at the University of Kentucky are teaming up with researchers at Michigan State University to develop cutting-edge simulations of hea...
uknow.uky.edu
July 22, 2025 at 9:15 PM
Excited to be working with Jonathan Wenk (University of Kentucky) and Lik-Chuan Lee (Michigan State University) on computer modeling of cardiac fibrosis.
uknow.uky.edu/research/uk-...
uknow.uky.edu/research/uk-...
Reposted by Ken Campbell
🎉 TRPA1-derful news 🎉 Dr. Dan Conklin has been successful in obtaining AHA funding to explore how inhaled anesthetics affect cardiorespiratory function through Transient Receptor Potential Ankyrin-1 (TRPA1). #AHA #TeamConklin #TRPA1 #cardiosky @ahascience.bsky.social @uoflenvirome.bsky.social
July 17, 2025 at 12:12 AM
🎉 TRPA1-derful news 🎉 Dr. Dan Conklin has been successful in obtaining AHA funding to explore how inhaled anesthetics affect cardiorespiratory function through Transient Receptor Potential Ankyrin-1 (TRPA1). #AHA #TeamConklin #TRPA1 #cardiosky @ahascience.bsky.social @uoflenvirome.bsky.social
Reposted by Ken Campbell
Congratulations to Dr. Marcin Wysoczynski, Associate Professor in the Center, on his appointment to the Editorial Board of Circulation Research. Well done, Dr. Wysoczynski. @ahajournals.bsky.social #cardiosky
July 8, 2025 at 1:46 AM
Congratulations to Dr. Marcin Wysoczynski, Associate Professor in the Center, on his appointment to the Editorial Board of Circulation Research. Well done, Dr. Wysoczynski. @ahajournals.bsky.social #cardiosky
Reposted by Ken Campbell
Our department @ucph.bsky.social is looking for a new faculty member! This is a nice environment for an ambitious PI with a research focus on cardiovascular system, metabolism and/or drug discovery! Happy to answer questions if you are interested!
164414 Tenure Track Assistant Professor or Associate Professor of Biomedical Sciences
jobportal.ku.dk
July 4, 2025 at 10:19 AM
Our department @ucph.bsky.social is looking for a new faculty member! This is a nice environment for an ambitious PI with a research focus on cardiovascular system, metabolism and/or drug discovery! Happy to answer questions if you are interested!
Congrats to Drs. Kampourakis, McDonald, Root and their collaborators on this cool study. Always excited to see new modulators of sarcomere function.
Modulation of striated-muscle contractility by a high-affinity myosin-targeting peptide: Biophysical Journal www.cell.com/biophysj/ful...
Modulation of striated-muscle contractility by a high-affinity myosin-targeting peptide: Biophysical Journal www.cell.com/biophysj/ful...
Modulation of striated-muscle contractility by a high-affinity myosin-targeting peptide
Myosin-based regulation has emerged as a fundamental new concept governing both cardiac
and skeletal muscle contractile function during both health and disease states. Myosin-targeted
therapeutics hav...
www.cell.com
July 3, 2025 at 1:17 PM
Congrats to Drs. Kampourakis, McDonald, Root and their collaborators on this cool study. Always excited to see new modulators of sarcomere function.
Modulation of striated-muscle contractility by a high-affinity myosin-targeting peptide: Biophysical Journal www.cell.com/biophysj/ful...
Modulation of striated-muscle contractility by a high-affinity myosin-targeting peptide: Biophysical Journal www.cell.com/biophysj/ful...
Reposted by Ken Campbell
The Collins lab welcomed Nora Anderson to the team today. Nora joins as a research technician, who will assist with our ongoing pregnancy studies. 🫀🤰#cardiosky
July 1, 2025 at 2:06 AM
The Collins lab welcomed Nora Anderson to the team today. Nora joins as a research technician, who will assist with our ongoing pregnancy studies. 🫀🤰#cardiosky
Reposted by Ken Campbell
Congratulations to Avery Kendall for their first of many papers being accepted for publication today. Watch this space for the next one! #cardiosky @apspublications.bsky.social
June 28, 2025 at 2:45 AM
Congratulations to Avery Kendall for their first of many papers being accepted for publication today. Watch this space for the next one! #cardiosky @apspublications.bsky.social