Camila Coelho, PhD MBA
@camilahcoelho.bsky.social
Human B cell responses to emerging pathogens 🦠
Icahn School of Medicine at Mount Sinai, NYC 🏙 🚕 🗽🍎
www.coelholab.com
Icahn School of Medicine at Mount Sinai, NYC 🏙 🚕 🗽🍎
www.coelholab.com
Check our new paper here!
👇🏼
👇🏼
Now online! Human monoclonal antibodies targeting A35 protect from death caused by mpox
Human monoclonal antibodies targeting A35 protect from death caused by mpox
Three potent mAbs against the conserved MPXV A35 protein block viral spread, protect against lethal infection in mice, and align with protective antibody responses in convalescent humans, establishing A35 as a key target for next-generation orthopoxvirus therapies.
dlvr.it
August 27, 2025 at 3:11 PM
Check our new paper here!
👇🏼
👇🏼
Reposted by Camila Coelho, PhD MBA
Three monoclonal antibodies targeting the mpox virus protein A35 have shown strong protection against severe disease in laboratory and animal models, indicating potential for new therapeutic approaches. doi.org/g9zg4h
Three potent human antibodies against mpox pave way for new protective therapies
A team from the Microbiology Department at the Icahn School of Medicine at Mount Sinai has discovered three powerful monoclonal antibodies from a person who had previously been infected with mpox (formerly known as monkeypox).
medicalxpress.com
August 26, 2025 at 8:06 PM
Three monoclonal antibodies targeting the mpox virus protein A35 have shown strong protection against severe disease in laboratory and animal models, indicating potential for new therapeutic approaches. doi.org/g9zg4h
Reposted by Camila Coelho, PhD MBA
Reposted by Camila Coelho, PhD MBA
Human monoclonal antibodies targeting A35 protect from death caused by monkeypox virus @cellcellpress.bsky.social @carolilucas.bsky.social @vivianasimonlab.bsky.social @mschotsaert.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
August 27, 2025 at 2:54 AM
Human monoclonal antibodies targeting A35 protect from death caused by monkeypox virus @cellcellpress.bsky.social @carolilucas.bsky.social @vivianasimonlab.bsky.social @mschotsaert.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Camila Coelho, PhD MBA
Exciting data from @camilahcoelho.bsky.social lab! Congratulations to the team!
Human monoclonal antibodies targeting A35 protect from death caused by monkeypox virus @cellcellpress.bsky.social @carolilucas.bsky.social @vivianasimonlab.bsky.social @mschotsaert.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
August 27, 2025 at 4:19 AM
Exciting data from @camilahcoelho.bsky.social lab! Congratulations to the team!
Reposted by Camila Coelho, PhD MBA
New paper from the Coelho lab with a modest contribution from us:
🚨 New article! Our study "Human monoclonal antibodies protect against death caused by mpox" is now published:
👉 www.cell.com/cell/fulltex...
[1/9]
👉 www.cell.com/cell/fulltex...
[1/9]
Human monoclonal antibodies targeting A35 protect from death caused by mpox
Three potent mAbs against the conserved MPXV A35 protein block viral spread, protect
against lethal infection in mice, and align with protective antibody responses in
convalescent humans, establishing...
www.cell.com
August 26, 2025 at 9:36 PM
New paper from the Coelho lab with a modest contribution from us:
Reposted by Camila Coelho, PhD MBA
Join us next Wednesday as we hear from the great work from the Ward lab!
ISV August Webinar: mark your calendars today! isv-online.org/event/isv-au...
ISV August Webinar
Title: TBC
Speaker: Andrew Ward, Scripps Research, United States
Time Zones:
America & Europe: 08:00 (PDT) |11:00 (EDT) | 16:00 (BST) | 17:00 (CEST)
Central & South America: 09:00 (Mexic...
isv-online.org
August 23, 2025 at 6:17 PM
Join us next Wednesday as we hear from the great work from the Ward lab!
Reposted by Camila Coelho, PhD MBA
4/ Structural studies revealed all 3 mAbs target a highly conserved epitope in the A35 dimer groove, shared across orthopoxviruses. This explains their breadth and potency.
August 26, 2025 at 3:55 PM
4/ Structural studies revealed all 3 mAbs target a highly conserved epitope in the A35 dimer groove, shared across orthopoxviruses. This explains their breadth and potency.
Reposted by Camila Coelho, PhD MBA
7/ Together, our findings establish A35 as a critical therapeutic target for mpox and related orthopoxviruses, paving the way for next-generation antibody therapies and improved vaccines.
August 26, 2025 at 3:55 PM
7/ Together, our findings establish A35 as a critical therapeutic target for mpox and related orthopoxviruses, paving the way for next-generation antibody therapies and improved vaccines.
Reposted by Camila Coelho, PhD MBA
🚨New Paper in Cell 🧵🔎
Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox.
We were very excited (and lucky!) to contribute to this collab. effort.
🦠“Human monoclonal antibodies targeting A35 protect from death caused by mpox”🦠
doi.org/10.1016/j.cell.2025.08.004
Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox.
We were very excited (and lucky!) to contribute to this collab. effort.
🦠“Human monoclonal antibodies targeting A35 protect from death caused by mpox”🦠
doi.org/10.1016/j.cell.2025.08.004
August 26, 2025 at 3:55 PM
🚨New Paper in Cell 🧵🔎
Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox.
We were very excited (and lucky!) to contribute to this collab. effort.
🦠“Human monoclonal antibodies targeting A35 protect from death caused by mpox”🦠
doi.org/10.1016/j.cell.2025.08.004
Happy to share our work led by the @camilahcoelho.bsky.social, on mAbs against mpox.
We were very excited (and lucky!) to contribute to this collab. effort.
🦠“Human monoclonal antibodies targeting A35 protect from death caused by mpox”🦠
doi.org/10.1016/j.cell.2025.08.004
🚨 New article! Our study "Human monoclonal antibodies protect against death caused by mpox" is now published:
👉 www.cell.com/cell/fulltex...
[1/9]
👉 www.cell.com/cell/fulltex...
[1/9]
Human monoclonal antibodies targeting A35 protect from death caused by mpox
Three potent mAbs against the conserved MPXV A35 protein block viral spread, protect
against lethal infection in mice, and align with protective antibody responses in
convalescent humans, establishing...
www.cell.com
August 26, 2025 at 3:29 PM
🚨 New article! Our study "Human monoclonal antibodies protect against death caused by mpox" is now published:
👉 www.cell.com/cell/fulltex...
[1/9]
👉 www.cell.com/cell/fulltex...
[1/9]
Join us next Wednesday as we hear from the great work from the Ward lab!
ISV August Webinar: mark your calendars today! isv-online.org/event/isv-au...
ISV August Webinar
Title: TBC
Speaker: Andrew Ward, Scripps Research, United States
Time Zones:
America & Europe: 08:00 (PDT) |11:00 (EDT) | 16:00 (BST) | 17:00 (CEST)
Central & South America: 09:00 (Mexic...
isv-online.org
August 23, 2025 at 6:17 PM
Join us next Wednesday as we hear from the great work from the Ward lab!
Reposted by Camila Coelho, PhD MBA
Such a great time at the #IUIS2025! Inspiring conferences by amazing scientists such as @belkaidlab.bsky.social @virusesimmunity.bsky.social @linterman.bsky.social. Also loved seeing rising stars like @camilahcoelho.bsky.social @marionbrunck.bsky.social. Thanks to James Allison for his lecture !! ❤️
August 22, 2025 at 6:56 PM
Such a great time at the #IUIS2025! Inspiring conferences by amazing scientists such as @belkaidlab.bsky.social @virusesimmunity.bsky.social @linterman.bsky.social. Also loved seeing rising stars like @camilahcoelho.bsky.social @marionbrunck.bsky.social. Thanks to James Allison for his lecture !! ❤️
Reposted by Camila Coelho, PhD MBA
Congratulations to former LJI trainee Dr. Camila Coelho (now at the Icahn School of Medicine at Mount Sinai)! 🎉
Dr. Coelho has been named a "Rising Star" by Union of Immunological Societies — an award for early-stage researchers who are revolutionizing the field! bit.ly/4mGyF3H #health #medicine
Dr. Coelho has been named a "Rising Star" by Union of Immunological Societies — an award for early-stage researchers who are revolutionizing the field! bit.ly/4mGyF3H #health #medicine
Camila Coelho, PhD, MBA, Named Rising Star by Union of Immunological Societies
bit.ly
August 12, 2025 at 8:00 PM
Congratulations to former LJI trainee Dr. Camila Coelho (now at the Icahn School of Medicine at Mount Sinai)! 🎉
Dr. Coelho has been named a "Rising Star" by Union of Immunological Societies — an award for early-stage researchers who are revolutionizing the field! bit.ly/4mGyF3H #health #medicine
Dr. Coelho has been named a "Rising Star" by Union of Immunological Societies — an award for early-stage researchers who are revolutionizing the field! bit.ly/4mGyF3H #health #medicine
Reposted by Camila Coelho, PhD MBA
Fascinating talk by rising star @camilahcoelho.bsky.social - Latin America representing @iuis-online.bsky.social #IUIS2025
August 21, 2025 at 1:23 PM
Fascinating talk by rising star @camilahcoelho.bsky.social - Latin America representing @iuis-online.bsky.social #IUIS2025
🚨 New Publication!!!
I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”.
www.cell.com/cell-reports... [1/4]
I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”.
www.cell.com/cell-reports... [1/4]
Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope
Rao et al. demonstrate that convergent somatic hypermutations in the light chain,
enriched within a sarbecovirus-specific public antibody clonotype, drive affinity
maturation. This antibody targets a ...
www.cell.com
August 12, 2025 at 6:52 PM
🚨 New Publication!!!
I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”.
www.cell.com/cell-reports... [1/4]
I’m thrilled to share our latest study, “Clonotype-Enriched Somatic Hypermutations Drive Affinity Maturation of a Public Human Antibody Targeting an Occluded Sarbecovirus Epitope”.
www.cell.com/cell-reports... [1/4]
Reposted by Camila Coelho, PhD MBA
Had a great time presenting my PhD work so far in @camilahcoelho.bsky.social’s lab at the Keystone Vaccinology meeting! Grateful for the chance to share and learn alongside such an inspiring community of scientists!
#KSVaccines25
#KSVaccines25
June 7, 2025 at 6:36 PM
Had a great time presenting my PhD work so far in @camilahcoelho.bsky.social’s lab at the Keystone Vaccinology meeting! Grateful for the chance to share and learn alongside such an inspiring community of scientists!
#KSVaccines25
#KSVaccines25
Reposted by Camila Coelho, PhD MBA
Labels matter and they influence policy. Thank you to the brilliant @camilahcoelho.bsky.social for making us rethink our default scientific terms to take away the unintended stigma to create a safer space. People like you help change the world.
Check our important piece below 👇!
"We urge authors, reviewers, and editors to revise the default use of MSM as an epidemiological label. Our intention is not to dismiss important epidemiological context but to prevent the stigmatization of affected populations."
@thelancetinfdis.bsky.social
"We urge authors, reviewers, and editors to revise the default use of MSM as an epidemiological label. Our intention is not to dismiss important epidemiological context but to prevent the stigmatization of affected populations."
@thelancetinfdis.bsky.social
July 17, 2025 at 2:22 PM
Labels matter and they influence policy. Thank you to the brilliant @camilahcoelho.bsky.social for making us rethink our default scientific terms to take away the unintended stigma to create a safer space. People like you help change the world.
Reposted by Camila Coelho, PhD MBA
We urge researchers, editors, and public health professionals to:
– Reassess default epidemiological labels
– Prioritize accuracy over legacy language
– Center transmission routes, not identities
#PublicHealth #Mpox #InfectiousDiseases #StigmaFreeScience
– Reassess default epidemiological labels
– Prioritize accuracy over legacy language
– Center transmission routes, not identities
#PublicHealth #Mpox #InfectiousDiseases #StigmaFreeScience
July 16, 2025 at 2:07 PM
We urge researchers, editors, and public health professionals to:
– Reassess default epidemiological labels
– Prioritize accuracy over legacy language
– Center transmission routes, not identities
#PublicHealth #Mpox #InfectiousDiseases #StigmaFreeScience
– Reassess default epidemiological labels
– Prioritize accuracy over legacy language
– Center transmission routes, not identities
#PublicHealth #Mpox #InfectiousDiseases #StigmaFreeScience
Check our important piece below 👇!
"We urge authors, reviewers, and editors to revise the default use of MSM as an epidemiological label. Our intention is not to dismiss important epidemiological context but to prevent the stigmatization of affected populations."
@thelancetinfdis.bsky.social
"We urge authors, reviewers, and editors to revise the default use of MSM as an epidemiological label. Our intention is not to dismiss important epidemiological context but to prevent the stigmatization of affected populations."
@thelancetinfdis.bsky.social
July 16, 2025 at 2:29 PM
Check our important piece below 👇!
"We urge authors, reviewers, and editors to revise the default use of MSM as an epidemiological label. Our intention is not to dismiss important epidemiological context but to prevent the stigmatization of affected populations."
@thelancetinfdis.bsky.social
"We urge authors, reviewers, and editors to revise the default use of MSM as an epidemiological label. Our intention is not to dismiss important epidemiological context but to prevent the stigmatization of affected populations."
@thelancetinfdis.bsky.social