Brant Isakson
@brantisakson.bsky.social
How do cells in the microcirculation talk? That’s my jam. Previously known as @conn_pann_fun on ol’ Twitter. I’ve been at UVA a lonnnnng time.
♥️🦕 physiology
♥️🦕 physiology
Reposted by Brant Isakson
Why travel to Denmark to collect samples from a giraffe's heart? @brantisakson.bsky.social lab members Skylar Loeb and @lukedunaway.bsky.social made the trip to learn more about diastolic heart failure. Red more: www.cvrc.virginia.edu/cvrc-trainee...
#cardiology #medsky
#cardiology #medsky
CVRC Trainees Travel Abroad to Collect a Giraffe Heart – Robert M. Berne Cardiovascular Research Center
www.cvrc.virginia.edu
July 11, 2025 at 4:48 PM
Why travel to Denmark to collect samples from a giraffe's heart? @brantisakson.bsky.social lab members Skylar Loeb and @lukedunaway.bsky.social made the trip to learn more about diastolic heart failure. Red more: www.cvrc.virginia.edu/cvrc-trainee...
#cardiology #medsky
#cardiology #medsky
Reposted by Brant Isakson
Excited to pre-release the latest from the lab on how arterial myocyte Panx1 controls vascular reactivity in diabetes. Massive effort from the M&M Team in collaboration with @brantisakson.bsky.social and Xiang Lab
Check our latest work from the M&M lab on the role of SMC Pannexin 1 in diabetic hyperglycemia! And thanks to everyone involved in this! Ole 💃 www.ahajournals.org/doi/10.1161/...
Arterial Myocyte Pannexin 1 Channel Controls Vascular Reactivity in Diabetic Hyperglycemia | Circulation Research
BACKGROUND: Diabetic hyperglycemia promotes vasoconstriction by activating an ATP-dependent P2Y11L (P2Y11-like receptor)/AC5 (adenylyl cyclase 5)/AKAP5 (A-kinase anchoring protein 5)/PKA
(protein kina...
www.ahajournals.org
July 10, 2025 at 7:37 PM
Excited to pre-release the latest from the lab on how arterial myocyte Panx1 controls vascular reactivity in diabetes. Massive effort from the M&M Team in collaboration with @brantisakson.bsky.social and Xiang Lab
Happy Donut Friday!
June 20, 2025 at 12:39 PM
Happy Donut Friday!
Happy Donut Friday—Love the Cville Donut selections! 🍩
June 13, 2025 at 1:09 PM
Happy Donut Friday—Love the Cville Donut selections! 🍩
Happy Donut Friday to all that celebrate!
May 23, 2025 at 4:01 PM
Happy Donut Friday to all that celebrate!
Happy Donut Friday! Sbrocco’s for the win!
May 16, 2025 at 12:40 PM
Happy Donut Friday! Sbrocco’s for the win!
Our first giraffe heart acquisition has caused an epic Isakson Lab Slack blowup this morning 🦒🦒
May 7, 2025 at 2:04 PM
Our first giraffe heart acquisition has caused an epic Isakson Lab Slack blowup this morning 🦒🦒
Guesses? Hint: not human/mouse/rat
April 30, 2025 at 8:27 PM
Guesses? Hint: not human/mouse/rat
Reposted by Brant Isakson
Headed to #APS2025! Two great talks tomorrow from the Isakson Lab in the MCS session. Wyatt Shug (8:30AM) will present on basophil-endothelial crosstalk, and Skylar Loeb (10:50AM) will present the novel identification and impact of hemoglobin-alpha in cardiac lymphatics. @brantisakson.bsky.social
April 23, 2025 at 11:14 PM
Headed to #APS2025! Two great talks tomorrow from the Isakson Lab in the MCS session. Wyatt Shug (8:30AM) will present on basophil-endothelial crosstalk, and Skylar Loeb (10:50AM) will present the novel identification and impact of hemoglobin-alpha in cardiac lymphatics. @brantisakson.bsky.social
Reposted by Brant Isakson
My father-in-law, Jack Strominger, and I wrote a letter to the @wsj.com editor about the current threats to science due to Trump's funding freeze. Please repost! www.wsj.com/opinion/scie...
Opinion | Science Suffers With Trump’s Funding Freeze
America’s scientific enterprise demands reliable stewardship, not destabilizing political intervention.
www.wsj.com
April 21, 2025 at 6:21 PM
My father-in-law, Jack Strominger, and I wrote a letter to the @wsj.com editor about the current threats to science due to Trump's funding freeze. Please repost! www.wsj.com/opinion/scie...
Some of the strong work by Melissa Luse rounding her PhD. Love the story, and I think it opens up some new ideas in endothelial lipid handling and overall questions roles for NO…
www.ahajournals.org/doi/10.1161/...
www.ahajournals.org/doi/10.1161/...
Nitrosation of CD36 Regulates Endothelial Function and Serum Lipids | Arteriosclerosis, Thrombosis, and Vascular Biology
BACKGROUND: During obesity, endothelial cells (ECs) become lipid laden, leading to endothelial
dysfunction. We tested posttranslational modification on CD36 that may regulate EC
lipid accumulation. ...
www.ahajournals.org
April 21, 2025 at 3:03 PM
Some of the strong work by Melissa Luse rounding her PhD. Love the story, and I think it opens up some new ideas in endothelial lipid handling and overall questions roles for NO…
www.ahajournals.org/doi/10.1161/...
www.ahajournals.org/doi/10.1161/...
Reposted by Brant Isakson
Want to stay current with cardiology at UVA? Check out our starter pack!
If you're a cardiologist at UVA and want to be included in the list, DM us!
go.bsky.app/3NVEjJ5
If you're a cardiologist at UVA and want to be included in the list, DM us!
go.bsky.app/3NVEjJ5
April 4, 2025 at 3:37 PM
Want to stay current with cardiology at UVA? Check out our starter pack!
If you're a cardiologist at UVA and want to be included in the list, DM us!
go.bsky.app/3NVEjJ5
If you're a cardiologist at UVA and want to be included in the list, DM us!
go.bsky.app/3NVEjJ5
Lab outing, snuggling baby goats!🐐🐐
March 30, 2025 at 9:49 PM
Lab outing, snuggling baby goats!🐐🐐
Reposted by Brant Isakson
@lukedunaway.bsky.social, PhD, recently received an @americanheart.bsky.social Career Development Award to study iron's role in chronic kidney disease. Luke is a postdoc in @brantisakson.bsky.social's Lab and member of our Cardiovascular Training Program. Congratulations!
#CardioSky #MedSky
#CardioSky #MedSky
Luke Dunaway, PhD, Wins AHA Award for Chronic Kidney Disease Research – Robert M. Berne Cardiovascular Research Center
www.cvrc.virginia.edu
March 20, 2025 at 5:15 PM
@lukedunaway.bsky.social, PhD, recently received an @americanheart.bsky.social Career Development Award to study iron's role in chronic kidney disease. Luke is a postdoc in @brantisakson.bsky.social's Lab and member of our Cardiovascular Training Program. Congratulations!
#CardioSky #MedSky
#CardioSky #MedSky
Happy Donut Friday! C’ville’s very own Belle for the win…
February 21, 2025 at 3:15 PM
Happy Donut Friday! C’ville’s very own Belle for the win…
some good distraction tonight from the political crazies
February 7, 2025 at 10:58 PM
some good distraction tonight from the political crazies
Happy Donut Friday!
February 7, 2025 at 3:33 PM
Happy Donut Friday!
Happy Donut Friday!
January 31, 2025 at 4:24 PM
Happy Donut Friday!
Reposted by Brant Isakson
Qunkasaura is the last dinosaur described in Spain, a large titanosaur that lived alongside Lohuecotitan at the Lo Hueco site, in the province of Cuenca
#paleoart
#paleoart
January 26, 2025 at 1:23 PM
Qunkasaura is the last dinosaur described in Spain, a large titanosaur that lived alongside Lohuecotitan at the Lo Hueco site, in the province of Cuenca
#paleoart
#paleoart
Happy donut Friday!🍩
January 17, 2025 at 1:54 PM
Happy donut Friday!🍩
🦕🦕 I’m happy this fun little book is finally out exploring how the physiology of the sauropod dino helped contribute to its dominance on earth for so long. However, I think I’ll stick to my day job 😁 🦕🦕
January 7, 2025 at 4:39 PM
🦕🦕 I’m happy this fun little book is finally out exploring how the physiology of the sauropod dino helped contribute to its dominance on earth for so long. However, I think I’ll stick to my day job 😁 🦕🦕
Happy Donut Friday to these three! Zuza received an AHA for work on Piezo2, Wyatt received BOTH an AHA and a F31 for work on basophils, and Skylar received an F31 for work on lymphatic alpha globin! Honored to have them in lab! (Pic from 2024 NAVBO)
December 20, 2024 at 7:26 PM
Happy Donut Friday to these three! Zuza received an AHA for work on Piezo2, Wyatt received BOTH an AHA and a F31 for work on basophils, and Skylar received an F31 for work on lymphatic alpha globin! Honored to have them in lab! (Pic from 2024 NAVBO)