Bradley Harris
bradleyomics.bsky.social
Bradley Harris
@bradleyomics.bsky.social
Postdoc @sangerinstitute.bsky.social | Lover of all things single-cell ‘omic, common complex disease and genetics. Anderson lab - http://andersonlab.info
Pinned
Delighted to share the first preprint of my postdoc in the @carlanderson.bsky.social lab www.medrxiv.org/content/10.1...! 🚨 A super exciting study I co-led with the very talented @tobioinformatics.bsky.social . Stay tuned to see what we learned about genetic susceptibility to complex disease. 🧬🧵 1/
Cell-type-resolved genetic regulatory variation shapes inflammatory bowel disease risk
Most genetic variants associated with complex diseases lie in non-coding regions, complicating efforts to identify effector genes and relevant cell types. Here, we map cis-eQTLs across 2.2 million sin...
www.medrxiv.org
Reposted by Bradley Harris
Scientists have uncovered hidden genetic drivers of conditions like IBD by stimulating immune cells. 🔬

The findings have resulted in a dataset called MacroMap, which offers insight into why some people are vulnerable to certain conditions.

sanger.ac.uk/news_item/ac...
Activated immune cells reveal hidden drivers of autoimmune diseases
A new resource, MacroMap, provides a rich dataset that researchers can use to explore genetic mechanisms behind complex diseases.
sanger.ac.uk
August 27, 2025 at 9:43 AM
Delighted to share the first preprint of my postdoc in the @carlanderson.bsky.social lab www.medrxiv.org/content/10.1...! 🚨 A super exciting study I co-led with the very talented @tobioinformatics.bsky.social . Stay tuned to see what we learned about genetic susceptibility to complex disease. 🧬🧵 1/
Cell-type-resolved genetic regulatory variation shapes inflammatory bowel disease risk
Most genetic variants associated with complex diseases lie in non-coding regions, complicating efforts to identify effector genes and relevant cell types. Here, we map cis-eQTLs across 2.2 million sin...
www.medrxiv.org
July 8, 2025 at 8:51 AM
Reposted by Bradley Harris
Preprint out today!

A team led by @tobioinformatics.bsky.social and Bradley Harris in @carlanderson.bsky.social ‘s lab has created the largest single-cell atlas of IBD tissues to date

www.medrxiv.org/content/10.1...
June 26, 2025 at 8:29 AM