Blas Chaves-Urbano
@blaschaves.bsky.social
PhD student at CNIO, Madrid, Spain | La Caixa INPhINIT Retaining Fellow
Reposted by Blas Chaves-Urbano
📢 New preprint out!
We are thrilled to introduce our framework to track #ongoingCIN by leveraging single-cell genomics and CIN signatures:
www.biorxiv.org/content/10.1...
We are thrilled to introduce our framework to track #ongoingCIN by leveraging single-cell genomics and CIN signatures:
www.biorxiv.org/content/10.1...
Tracking ongoing chromosomal instability using single-cell whole-genome sequencing
Chromosomal instability (CIN) generates aneuploid genomes that are characteristic of most cancers. While bulk genome sequencing reveals historical CIN, it lacks the resolution to identify ongoing CIN ...
www.biorxiv.org
November 28, 2025 at 1:07 PM
📢 New preprint out!
We are thrilled to introduce our framework to track #ongoingCIN by leveraging single-cell genomics and CIN signatures:
www.biorxiv.org/content/10.1...
We are thrilled to introduce our framework to track #ongoingCIN by leveraging single-cell genomics and CIN signatures:
www.biorxiv.org/content/10.1...
Reposted by Blas Chaves-Urbano
🚨Chemo treatment upgrade!🚨
Check out our approach to modernise chemotherapy treatment published today in @natgenet.nature.com. From @cniostopcancer.bsky.social #TailorBio @cruk-ci.bsky.social www.nature.com/articles/s41... More details 👇
Check out our approach to modernise chemotherapy treatment published today in @natgenet.nature.com. From @cniostopcancer.bsky.social #TailorBio @cruk-ci.bsky.social www.nature.com/articles/s41... More details 👇
www.nature.com
June 23, 2025 at 9:03 AM
🚨Chemo treatment upgrade!🚨
Check out our approach to modernise chemotherapy treatment published today in @natgenet.nature.com. From @cniostopcancer.bsky.social #TailorBio @cruk-ci.bsky.social www.nature.com/articles/s41... More details 👇
Check out our approach to modernise chemotherapy treatment published today in @natgenet.nature.com. From @cniostopcancer.bsky.social #TailorBio @cruk-ci.bsky.social www.nature.com/articles/s41... More details 👇
Reposted by Blas Chaves-Urbano
📢OUT TODAY @natgenet.nature.com
📰Predicting resistance to chemotherapy using chromosomal instability signatures.
By @jsneaththompson.bsky.social, @gmaci.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...
📰Predicting resistance to chemotherapy using chromosomal instability signatures.
By @jsneaththompson.bsky.social, @gmaci.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...
June 23, 2025 at 2:18 PM
📢OUT TODAY @natgenet.nature.com
📰Predicting resistance to chemotherapy using chromosomal instability signatures.
By @jsneaththompson.bsky.social, @gmaci.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...
📰Predicting resistance to chemotherapy using chromosomal instability signatures.
By @jsneaththompson.bsky.social, @gmaci.bsky.social and colleagues.
⬇️
www.nature.com/articles/s41...
Reposted by Blas Chaves-Urbano
The days of one-size-fits-all chemotherapy are ending.
Researchers at our Institute, @cniostopcancer.bsky.social & Tailor Bio have developed a test that predicts resistance to common chemo drugs — paving the way for personalised cancer treatment.
Find out more 👉 www.cruk.cam.ac.uk/news/scienti...
Researchers at our Institute, @cniostopcancer.bsky.social & Tailor Bio have developed a test that predicts resistance to common chemo drugs — paving the way for personalised cancer treatment.
Find out more 👉 www.cruk.cam.ac.uk/news/scienti...
June 23, 2025 at 9:00 AM
The days of one-size-fits-all chemotherapy are ending.
Researchers at our Institute, @cniostopcancer.bsky.social & Tailor Bio have developed a test that predicts resistance to common chemo drugs — paving the way for personalised cancer treatment.
Find out more 👉 www.cruk.cam.ac.uk/news/scienti...
Researchers at our Institute, @cniostopcancer.bsky.social & Tailor Bio have developed a test that predicts resistance to common chemo drugs — paving the way for personalised cancer treatment.
Find out more 👉 www.cruk.cam.ac.uk/news/scienti...
Reposted by Blas Chaves-Urbano
The paper is published in @natgenet.nature.com. First authors: @bhernando.bsky.social, @jsneaththompson.bsky.social and Laura Madrid. With collaborations from Tailor Bio and @cam.ac.uk.
Funding: @saludisciii.bsky.social @cienciagob.bsky.social @cruk-ci.bsky.social y @lacaixa.bsky.social
Funding: @saludisciii.bsky.social @cienciagob.bsky.social @cruk-ci.bsky.social y @lacaixa.bsky.social
June 23, 2025 at 4:14 PM
The paper is published in @natgenet.nature.com. First authors: @bhernando.bsky.social, @jsneaththompson.bsky.social and Laura Madrid. With collaborations from Tailor Bio and @cam.ac.uk.
Funding: @saludisciii.bsky.social @cienciagob.bsky.social @cruk-ci.bsky.social y @lacaixa.bsky.social
Funding: @saludisciii.bsky.social @cienciagob.bsky.social @cruk-ci.bsky.social y @lacaixa.bsky.social
A pleasure to be at the fantastic #EACR2025 and present my research project! Looking forward for cool scientific discussions with amazing cancer researchers and friends @helloeacr.bsky.social @cniostopcancer.bsky.social @gmaci.bsky.social
June 17, 2025 at 8:46 AM
A pleasure to be at the fantastic #EACR2025 and present my research project! Looking forward for cool scientific discussions with amazing cancer researchers and friends @helloeacr.bsky.social @cniostopcancer.bsky.social @gmaci.bsky.social
Reposted by Blas Chaves-Urbano
If tumour genome evolution is deterministic, can we forecast genomic changes? Yes we can! At least for oncogene amps and tumour suppressor dels. @bhernando.bsky.social Angel Fernandez-Sanroman present our method for forecasting driver gene copy number change. Preprint: bit.ly/4kxF14y ⬇️1/
Forecasting oncogene amplification and tumour suppressor deletion
Oncogene amplification and tumour suppressor deletion can drive tumour initiation, progression and treatment resistance. Detection at diagnosis often signals poor prognosis, but it can also enable opp...
bit.ly
June 10, 2025 at 2:15 PM
If tumour genome evolution is deterministic, can we forecast genomic changes? Yes we can! At least for oncogene amps and tumour suppressor dels. @bhernando.bsky.social Angel Fernandez-Sanroman present our method for forecasting driver gene copy number change. Preprint: bit.ly/4kxF14y ⬇️1/
Reposted by Blas Chaves-Urbano
We are hiring! Opportunity for a project manager to oversee all aspects of a multi-centre clinical research project to implement an AI-based genomic test that predicts resistance to chemotherapy - Madrid, Spain. PM for more details. Deadline 25 January! www.cnio.es/en/empleo/re...
January 16, 2025 at 5:38 PM
We are hiring! Opportunity for a project manager to oversee all aspects of a multi-centre clinical research project to implement an AI-based genomic test that predicts resistance to chemotherapy - Madrid, Spain. PM for more details. Deadline 25 January! www.cnio.es/en/empleo/re...