Benjamin Buchfink
@bbuchfink.bsky.social
Independent scientist, Tübingen, Germany. Developer of the DIAMOND protein aligner. https://github.com/bbuchfink/diamond
DIAMOND v2.1.15 now supports all taxonomy features for BLAST databases, and support for using BLAST databases has also been added to the Bioconda version github.com/bbuchfink/di...
GitHub - bbuchfink/diamond: Accelerated BLAST compatible local sequence aligner.
Accelerated BLAST compatible local sequence aligner. - bbuchfink/diamond
github.com
October 28, 2025 at 4:45 PM
DIAMOND v2.1.15 now supports all taxonomy features for BLAST databases, and support for using BLAST databases has also been added to the Bioconda version github.com/bbuchfink/di...
Reposted by Benjamin Buchfink
Reposted by Benjamin Buchfink
Ragnarok: a flexible and RApid GeNe Annotation (ROcKs) pipeline deployed through Nextflow https://www.biorxiv.org/content/10.1101/2025.10.03.680343v1
October 5, 2025 at 1:47 AM
Ragnarok: a flexible and RApid GeNe Annotation (ROcKs) pipeline deployed through Nextflow https://www.biorxiv.org/content/10.1101/2025.10.03.680343v1
Reposted by Benjamin Buchfink
Comprehensive taxonomic identification of microbial species in metagenomic data using SingleM and Sandpiper. #Metagenomics #MicrobialCommunities #Bioinformatics @natbiotech.nature.com 🧬 🖥️
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 31, 2025 at 8:31 AM
Comprehensive taxonomic identification of microbial species in metagenomic data using SingleM and Sandpiper. #Metagenomics #MicrobialCommunities #Bioinformatics @natbiotech.nature.com 🧬 🖥️
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Benjamin Buchfink
TaxTriage: An Open-Source Metagenomic Sequencing Data Analysis Pipeline Enabling Putative Pathogen Detection. #Metagenomics #Sequencing #PathogenDetection #Bioinformatics @biorxiv-bioinfo.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 2, 2025 at 9:15 AM
TaxTriage: An Open-Source Metagenomic Sequencing Data Analysis Pipeline Enabling Putative Pathogen Detection. #Metagenomics #Sequencing #PathogenDetection #Bioinformatics @biorxiv-bioinfo.bsky.social
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Benjamin Buchfink
OrthoFinder just dropped a major update
It’s faster, more accurate, and ready for thousands of genomes
Let’s break it down (1/10)
github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...
It’s faster, more accurate, and ready for thousands of genomes
Let’s break it down (1/10)
github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...
July 16, 2025 at 5:51 PM
OrthoFinder just dropped a major update
It’s faster, more accurate, and ready for thousands of genomes
Let’s break it down (1/10)
github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...
It’s faster, more accurate, and ready for thousands of genomes
Let’s break it down (1/10)
github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...
Reposted by Benjamin Buchfink
Out in @natbiotech.nature.com: Metagenome taxonomy profilers usually ignore unknown species. SingleM is an accurate profiler which doesn't, even detecting phyla with no MAGs. Profiles of 700,000 metagenomes at sandpiper.qut.edu.au. A 🧵
July 16, 2025 at 9:59 PM
Out in @natbiotech.nature.com: Metagenome taxonomy profilers usually ignore unknown species. SingleM is an accurate profiler which doesn't, even detecting phyla with no MAGs. Profiles of 700,000 metagenomes at sandpiper.qut.edu.au. A 🧵
DIAMOND v2.1.12 provides support for the new NCBI taxonomic ranks and various other fixes. github.com/bbuchfink/di...
GitHub - bbuchfink/diamond: Accelerated BLAST compatible local sequence aligner.
Accelerated BLAST compatible local sequence aligner. - bbuchfink/diamond
github.com
June 2, 2025 at 4:23 PM
DIAMOND v2.1.12 provides support for the new NCBI taxonomic ranks and various other fixes. github.com/bbuchfink/di...
Reposted by Benjamin Buchfink
Industry friends, now is the time for MUCH more speaking out on behalf of academic colleagues under duress. Here are core open source methods that many of your products doubtlessly depend on either directly or indirectly (see en.wikipedia.org/wiki/HMMER) being abruptly defunded. Make noise.
May 29, 2025 at 2:39 PM
Industry friends, now is the time for MUCH more speaking out on behalf of academic colleagues under duress. Here are core open source methods that many of your products doubtlessly depend on either directly or indirectly (see en.wikipedia.org/wiki/HMMER) being abruptly defunded. Make noise.
Reposted by Benjamin Buchfink
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
May 22, 2025 at 12:42 PM
NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.
Reposted by Benjamin Buchfink
NIH just early-expired its 1st & only software NOFO: “Building Sustainable Software Tools for Open Science.” Our proposal supported lab automation software infrastructure, with backing from major robotics companies. I guess “sustainable” is too risky now. So much for funding the STEM workforce.
May 19, 2025 at 7:14 PM
NIH just early-expired its 1st & only software NOFO: “Building Sustainable Software Tools for Open Science.” Our proposal supported lab automation software infrastructure, with backing from major robotics companies. I guess “sustainable” is too risky now. So much for funding the STEM workforce.
DIAMOND v2.1.11 is now available, providing numerous improvements and fixes. github.com/bbuchfink/di...
GitHub - bbuchfink/diamond: Accelerated BLAST compatible local sequence aligner.
Accelerated BLAST compatible local sequence aligner. - bbuchfink/diamond
github.com
January 25, 2025 at 9:46 AM
DIAMOND v2.1.11 is now available, providing numerous improvements and fixes. github.com/bbuchfink/di...