Babis Galouzis
@babisgalouzis.bsky.social
Biologist into evolution and development
EMBO fellow at EMBL
EMBO fellow at EMBL
This is so cool! It’s also nice to see how careful genetic dissection of loci is still at the forefront of discovery!
Ever wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one?
Check our latest preprint, led by @mmasoura.bsky.social, to find out!
www.biorxiv.org/content/10.1...
Check our latest preprint, led by @mmasoura.bsky.social, to find out!
www.biorxiv.org/content/10.1...
Promoter-proximal gatekeepers restrict pleiotropic enhancer inputs to achieve tissue specificity
Developmental enhancers are central regulatory elements that can activate multiple genes, yet how they selectively regulate one gene over its neighbours remains unclear. Using the Drosophila twist E3 ...
www.biorxiv.org
October 18, 2025 at 8:00 AM
This is so cool! It’s also nice to see how careful genetic dissection of loci is still at the forefront of discovery!
Check our latest with Yacine Kherdjemil and @eileen-furlong.bsky.social and our colleagues, where we show Chip (Ldb1) is essential only at a narrow window of embryogenesis overlapping ZGA. It functionally and physically bridges CBP to Zelda to regulate gene expression. www.cell.com/molecular-ce...
Chip (Ldb1) is a putative cofactor of Zelda forming a functional bridge to CBP during zygotic genome activation
Chip/Ldb1 is a crucial cofactor regulating enhancer function and chromatin interactions.
Using optogenetics, Galouzis, Kherdjemil et al. show that Chip is only essential during
zygotic genome activati...
www.cell.com
June 10, 2025 at 7:49 AM
Check our latest with Yacine Kherdjemil and @eileen-furlong.bsky.social and our colleagues, where we show Chip (Ldb1) is essential only at a narrow window of embryogenesis overlapping ZGA. It functionally and physically bridges CBP to Zelda to regulate gene expression. www.cell.com/molecular-ce...