Basile Beaud Benyahia
@babebe.bsky.social
Microbiologist in Simonetta Gribaldo’s lab at Institut Pasteur. Love membranes, evolution and bacteria that never want to grow the way i want them to 🥲✨🔮
Reposted by Basile Beaud Benyahia
Preprint on the permeability of Gram+ bacterial cell wall from a few months ago. Intriguing findings, elegant methodology. Cell wall is largely impermeable to molecule sizes of mNeonGreen (27kDa) and above. How do larger secreted proteins get through? www.biorxiv.org/content/10.1... #microsky
www.biorxiv.org
February 9, 2026 at 11:30 AM
Preprint on the permeability of Gram+ bacterial cell wall from a few months ago. Intriguing findings, elegant methodology. Cell wall is largely impermeable to molecule sizes of mNeonGreen (27kDa) and above. How do larger secreted proteins get through? www.biorxiv.org/content/10.1... #microsky
Reposted by Basile Beaud Benyahia
Look at this 🙂 #CryoEM
Structural basis for CTCF-mediated chromatin organization by @lucas.farnunglab.com @voslab.org
www.biorxiv.org/content/10.6...
Structural basis for CTCF-mediated chromatin organization by @lucas.farnunglab.com @voslab.org
www.biorxiv.org/content/10.6...
February 9, 2026 at 8:32 AM
Look at this 🙂 #CryoEM
Structural basis for CTCF-mediated chromatin organization by @lucas.farnunglab.com @voslab.org
www.biorxiv.org/content/10.6...
Structural basis for CTCF-mediated chromatin organization by @lucas.farnunglab.com @voslab.org
www.biorxiv.org/content/10.6...
Reposted by Basile Beaud Benyahia
Extremophile alert!
Registration is OPEN for the 2026 EMBO Archaeal workshop in Cambridge.
Spaces are limited, so register soon with an abstract if you’d like to give a talk.
If you can’t come in person, we are welcoming virtual attendees. So join us online where all talks will be screened!
Registration is OPEN for the 2026 EMBO Archaeal workshop in Cambridge.
Spaces are limited, so register soon with an abstract if you’d like to give a talk.
If you can’t come in person, we are welcoming virtual attendees. So join us online where all talks will be screened!
Sign up now for the EMBO Workshop "#MolecularBiology of #Archaea: Life Through the Prism of Archaea" in Cambridge, UK, 6–10 July 2026.
Deadline: 15 April
https://meetings.embo.org/event/26-archaea
#EMBOArchaeaBiology #EMBOevents #CellBiology #StructuralBiology #ecology #evolution #biophysics 🧪
Deadline: 15 April
https://meetings.embo.org/event/26-archaea
#EMBOArchaeaBiology #EMBOevents #CellBiology #StructuralBiology #ecology #evolution #biophysics 🧪
February 5, 2026 at 3:58 PM
Extremophile alert!
Registration is OPEN for the 2026 EMBO Archaeal workshop in Cambridge.
Spaces are limited, so register soon with an abstract if you’d like to give a talk.
If you can’t come in person, we are welcoming virtual attendees. So join us online where all talks will be screened!
Registration is OPEN for the 2026 EMBO Archaeal workshop in Cambridge.
Spaces are limited, so register soon with an abstract if you’d like to give a talk.
If you can’t come in person, we are welcoming virtual attendees. So join us online where all talks will be screened!
Reposted by Basile Beaud Benyahia
I’m looking for two postdoctoral scientists in experimental evolution to join my team from April 2026 (or soon after). Please share! fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...
Two postdoctoral positions (3-year) in Experimental Evolution of Methanogenic Microbiomes in Bioelectrochemical Systems
Application deadline: 4 March 2026 at 23:59 hours local Danish time
fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com
February 3, 2026 at 10:34 AM
I’m looking for two postdoctoral scientists in experimental evolution to join my team from April 2026 (or soon after). Please share! fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...
Looking for a deep dive into oxidoreductase distribution, structural plasticity & evolution across prokarya?
This new paper has you covered. 🐣
Big work just out from @pierresimongarcia.bsky.social , now a freshly minted PI.
This new paper has you covered. 🐣
Big work just out from @pierresimongarcia.bsky.social , now a freshly minted PI.
Passioned by #bioenergetics? Do not miss our new article on the evolutionary history of oxidoreductases with G. Borrel and @sgribaldo.bsky.social @archaeal.bsky.social @valdeanda.bsky.social @pasteur.fr @cnrs.fr @cnrsbiologie.bsky.social @natecoevo.nature.com (www.nature.com/articles/s41...).
Evolution and diversity of oxidoreductases involved in redox balance and energy conservation - Nature Ecology & Evolution
HORBEC are protein complexes involved in the regulation of redox balance and energy conservation. The authors develop a bioinformatic tool for HORBEC annotation in bacterial and archaeal genomes and r...
www.nature.com
February 3, 2026 at 12:50 PM
Looking for a deep dive into oxidoreductase distribution, structural plasticity & evolution across prokarya?
This new paper has you covered. 🐣
Big work just out from @pierresimongarcia.bsky.social , now a freshly minted PI.
This new paper has you covered. 🐣
Big work just out from @pierresimongarcia.bsky.social , now a freshly minted PI.
Reposted by Basile Beaud Benyahia
We analyzed the distribution of 31 HORBEC in over 4,000 bacterial and archaeal genomes. We propose a homogeneous nomenclature of HORBEC and their components and developed a tool, HORBEC-Finder, for automatic annotation from genomes(try it here! doi.org/10.6084/m9.f...).
February 3, 2026 at 10:52 AM
We analyzed the distribution of 31 HORBEC in over 4,000 bacterial and archaeal genomes. We propose a homogeneous nomenclature of HORBEC and their components and developed a tool, HORBEC-Finder, for automatic annotation from genomes(try it here! doi.org/10.6084/m9.f...).
Reposted by Basile Beaud Benyahia
Finally, we reconstructed the labyrinthic evolutionary history of HORBEC, from two ancient modules to the wide diversity that we observe in contemporary organisms.
February 3, 2026 at 10:52 AM
Finally, we reconstructed the labyrinthic evolutionary history of HORBEC, from two ancient modules to the wide diversity that we observe in contemporary organisms.
Reposted by Basile Beaud Benyahia
Passioned by #bioenergetics? Do not miss our new article on the evolutionary history of oxidoreductases with G. Borrel and @sgribaldo.bsky.social @archaeal.bsky.social @valdeanda.bsky.social @pasteur.fr @cnrs.fr @cnrsbiologie.bsky.social @natecoevo.nature.com (www.nature.com/articles/s41...).
Evolution and diversity of oxidoreductases involved in redox balance and energy conservation - Nature Ecology & Evolution
HORBEC are protein complexes involved in the regulation of redox balance and energy conservation. The authors develop a bioinformatic tool for HORBEC annotation in bacterial and archaeal genomes and r...
www.nature.com
February 3, 2026 at 10:52 AM
Passioned by #bioenergetics? Do not miss our new article on the evolutionary history of oxidoreductases with G. Borrel and @sgribaldo.bsky.social @archaeal.bsky.social @valdeanda.bsky.social @pasteur.fr @cnrs.fr @cnrsbiologie.bsky.social @natecoevo.nature.com (www.nature.com/articles/s41...).
Reposted by Basile Beaud Benyahia
Full house for @wcratcliff.bsky.social’s 45-min summary of 15 years of experimental evolution (including 8 years of MuLTEE) @pasteur.fr
January 26, 2026 at 2:46 PM
Full house for @wcratcliff.bsky.social’s 45-min summary of 15 years of experimental evolution (including 8 years of MuLTEE) @pasteur.fr
Reposted by Basile Beaud Benyahia
A family of archaeal hibernation factors that bind in tandem and protect ribosomes in dormant cells https://www.biorxiv.org/content/10.64898/2026.01.19.700200v1
January 19, 2026 at 9:16 PM
A family of archaeal hibernation factors that bind in tandem and protect ribosomes in dormant cells https://www.biorxiv.org/content/10.64898/2026.01.19.700200v1
Reposted by Basile Beaud Benyahia
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
research.pasteur.fr
December 8, 2025 at 8:53 AM
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Reposted by Basile Beaud Benyahia
🏆 Institut Pasteur Canetti Prize 2025 awarded to Céline Loot for her innovative contributions to infectious disease research.
This annual Institut Pasteur prize (€15K) honors scientific excellence, funded by the Canetti family legacy.
Congratulations Céline 👏
This annual Institut Pasteur prize (€15K) honors scientific excellence, funded by the Canetti family legacy.
Congratulations Céline 👏
December 17, 2025 at 9:14 AM
🏆 Institut Pasteur Canetti Prize 2025 awarded to Céline Loot for her innovative contributions to infectious disease research.
This annual Institut Pasteur prize (€15K) honors scientific excellence, funded by the Canetti family legacy.
Congratulations Céline 👏
This annual Institut Pasteur prize (€15K) honors scientific excellence, funded by the Canetti family legacy.
Congratulations Céline 👏
Reposted by Basile Beaud Benyahia
indeed, 𝘙𝘶𝘨𝘰𝘴𝘪𝘵𝘢𝘭𝘦𝘢 𝘰𝘳𝘺𝘻𝘢𝘦 looke like fusilli, which are notably better at holding on salsa di pomodoro than spaghetti... and as pasta addicts, we fell instantly in love with the shape of this newly described alphaproteo from the Rhizobiales 🤭
#MicroSky
#MicroSky
December 10, 2025 at 7:52 PM
indeed, 𝘙𝘶𝘨𝘰𝘴𝘪𝘵𝘢𝘭𝘦𝘢 𝘰𝘳𝘺𝘻𝘢𝘦 looke like fusilli, which are notably better at holding on salsa di pomodoro than spaghetti... and as pasta addicts, we fell instantly in love with the shape of this newly described alphaproteo from the Rhizobiales 🤭
#MicroSky
#MicroSky
Reposted by Basile Beaud Benyahia
This is excellent. But when will we be able to get it? The filter I mean. Someone will try to sell you a washing-machine fish, don't fall for it.
Fish-inspired filter removes 99% of microplastics from washing machine wastewater
Wastewater from washing machines is considered a major source of microplastics—tiny plastic particles that are suspected of harming human and animal health. Researchers at the University of Bonn have ...
techxplore.com
December 7, 2025 at 9:24 PM
This is excellent. But when will we be able to get it? The filter I mean. Someone will try to sell you a washing-machine fish, don't fall for it.
Reposted by Basile Beaud Benyahia
I am profoundly honored and grateful to be receiving the Impulscience Prize from the Fondation Bettencourt Schueller!
This grant will be the major support of my lab for the next 5 years.
Thank you for believing in our work and in our vision!
www.fondationbs.org/en/our-commu...
This grant will be the major support of my lab for the next 5 years.
Thank you for believing in our work and in our vision!
www.fondationbs.org/en/our-commu...
Camille Berthelot
In women, the uterine lining undergoes cyclical changes under the influence of sex hormones in preparation for a possible pregnancy: it differentiates, break
www.fondationbs.org
December 5, 2025 at 12:38 PM
I am profoundly honored and grateful to be receiving the Impulscience Prize from the Fondation Bettencourt Schueller!
This grant will be the major support of my lab for the next 5 years.
Thank you for believing in our work and in our vision!
www.fondationbs.org/en/our-commu...
This grant will be the major support of my lab for the next 5 years.
Thank you for believing in our work and in our vision!
www.fondationbs.org/en/our-commu...
Reposted by Basile Beaud Benyahia
An Asgard Archaeon (Lokiarchaeum ossiferum) growing and retracting its arms
December 3, 2025 at 8:32 PM
An Asgard Archaeon (Lokiarchaeum ossiferum) growing and retracting its arms
Reposted by Basile Beaud Benyahia
...deserves hashtags #Archaea #ArchaeaSky #MicroSky
wonder what name you will come up for the "tiny arms" that are clearly not pili, not archaella, not pseudopodia either...
pseudobracchia ?
(not claiming to be the first, I talked of "tiny arms" here > smallthingsconsidered.blog/schaechter/2...)
wonder what name you will come up for the "tiny arms" that are clearly not pili, not archaella, not pseudopodia either...
pseudobracchia ?
(not claiming to be the first, I talked of "tiny arms" here > smallthingsconsidered.blog/schaechter/2...)
An Asgard Archaeon (Lokiarchaeum ossiferum) growing and retracting its arms
December 4, 2025 at 9:50 PM
...deserves hashtags #Archaea #ArchaeaSky #MicroSky
wonder what name you will come up for the "tiny arms" that are clearly not pili, not archaella, not pseudopodia either...
pseudobracchia ?
(not claiming to be the first, I talked of "tiny arms" here > smallthingsconsidered.blog/schaechter/2...)
wonder what name you will come up for the "tiny arms" that are clearly not pili, not archaella, not pseudopodia either...
pseudobracchia ?
(not claiming to be the first, I talked of "tiny arms" here > smallthingsconsidered.blog/schaechter/2...)
Reposted by Basile Beaud Benyahia
Reposted by Basile Beaud Benyahia
#Archaea #ArchaeaSky #MicroSky
exceptional work, hiro & team 👏👏👏
it's wonderful to see 𝘓. 𝘰𝘴𝘴𝘪𝘧𝘦𝘳𝘶𝘮 dancing. live videos reveal so much more than stills!
ALT source: www.biorxiv.org/content/10.1...
exceptional work, hiro & team 👏👏👏
it's wonderful to see 𝘓. 𝘰𝘴𝘴𝘪𝘧𝘦𝘳𝘶𝘮 dancing. live videos reveal so much more than stills!
ALT source: www.biorxiv.org/content/10.1...
December 3, 2025 at 7:54 PM
#Archaea #ArchaeaSky #MicroSky
exceptional work, hiro & team 👏👏👏
it's wonderful to see 𝘓. 𝘰𝘴𝘴𝘪𝘧𝘦𝘳𝘶𝘮 dancing. live videos reveal so much more than stills!
ALT source: www.biorxiv.org/content/10.1...
exceptional work, hiro & team 👏👏👏
it's wonderful to see 𝘓. 𝘰𝘴𝘴𝘪𝘧𝘦𝘳𝘶𝘮 dancing. live videos reveal so much more than stills!
ALT source: www.biorxiv.org/content/10.1...
Reposted by Basile Beaud Benyahia
Each such discovery is a game changer for our understanding of eukaryote evolution, and this paper is no exception. Meet Solarion, which displays yet again novel types of subcellular structures. Congrats to all authors on a fascinating story. #protistsonsky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Rare microbial relict sheds light on an ancient eukaryotic supergroup - Nature
The discovery of an unusual protist named Solarion arienae, which has a mitochondrial genome with some intriguing features, provides insight into the early radiation of eukaryotic groups.
www.nature.com
November 21, 2025 at 9:30 AM
Each such discovery is a game changer for our understanding of eukaryote evolution, and this paper is no exception. Meet Solarion, which displays yet again novel types of subcellular structures. Congrats to all authors on a fascinating story. #protistsonsky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Basile Beaud Benyahia
rdcu.be/eRxNf here our new study on the characterization of the lipopolysaccharide holotranslocon, LptDE and the newly identified subunits LptM and LptY. Great collaboration with @fronzeslab.bsky.social @pstansfeld.bsky.social @JulienMarcoux @YvesQuentin
Structural basis of lipopolysaccharide assembly by the outer membrane translocon holo-complex
Nature Communications - The asymmetric distribution of lipopolysaccharide (LPS) on the surface of the bacterial outer membrane is essential and crucial for antibiotic resistance. Here, authors...
rdcu.be
November 24, 2025 at 4:08 PM
rdcu.be/eRxNf here our new study on the characterization of the lipopolysaccharide holotranslocon, LptDE and the newly identified subunits LptM and LptY. Great collaboration with @fronzeslab.bsky.social @pstansfeld.bsky.social @JulienMarcoux @YvesQuentin
Reposted by Basile Beaud Benyahia
Cryo plunging at sea in high winds - Luke at the helm
November 16, 2025 at 5:37 PM
Cryo plunging at sea in high winds - Luke at the helm
Reposted by Basile Beaud Benyahia
Our new paper is out in @narjournal.bsky.social We show that natural transformation enables bacteria to shuffle integron cassettes, boosting their phenotypic diversity.
academic.oup.com/nar/article/... 1/5
academic.oup.com/nar/article/... 1/5
Bacterial natural transformation drives cassette shuffling and simplifies recombination in chromosomal integrons
Abstract. Integrons act as biobanks of gene cassettes conferring functions crucial for bacterial defense, including protection against phages and antibioti
academic.oup.com
November 17, 2025 at 3:44 PM
Our new paper is out in @narjournal.bsky.social We show that natural transformation enables bacteria to shuffle integron cassettes, boosting their phenotypic diversity.
academic.oup.com/nar/article/... 1/5
academic.oup.com/nar/article/... 1/5
Reposted by Basile Beaud Benyahia
Assembly, architecture and functional roles of microbial surface layers
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Assembly, architecture and functional roles of microbial surface layers - Nature Reviews Microbiology
Surface layers (S-layers) are ubiquitous protein assemblies that coat prokaryotic cells, with their functional roles increasingly coming into focus. In this Review, Isbilir and colleagues discuss rece...
www.nature.com
November 13, 2025 at 8:14 PM
Assembly, architecture and functional roles of microbial surface layers
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...
Review article published in @natrevmicro.nature.com with @bupbuse.bsky.social, Andriko von Kügelgen and @vikramalva.bsky.social.
S-layers are everywhere!
www.nature.com/articles/s41...