AnneWe
@annewe.bsky.social
Chocoholic. Bioinformatician. Geek. Scout. Bicyclist.
#ARTxSCIENCE2025 - When #science meets art and reveals ongoing #stemcell research with the potential to transform the lives of people with so far incurable diseases. See all the beautiful entries and cast your vote for your favorite before September 22nd: renew.science/artxscience/
September 13, 2025 at 10:56 AM
#ARTxSCIENCE2025 - When #science meets art and reveals ongoing #stemcell research with the potential to transform the lives of people with so far incurable diseases. See all the beautiful entries and cast your vote for your favorite before September 22nd: renew.science/artxscience/
Reposted by AnneWe
We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social.
www.science.org/doi/10.1126/...
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www.science.org/doi/10.1126/...
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Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics
Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...
www.science.org
August 22, 2025 at 6:03 AM
We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social.
www.science.org/doi/10.1126/...
🧵
www.science.org/doi/10.1126/...
🧵
Reposted by AnneWe
It’s always a bit awkward to write about personal experiences. I tried to touch on what Pride means to me and ended up reflecting on heteronormativity, passing, and allyship. Thank you @slefkopoulos.bsky.social for the great opportunity! @ucph.bsky.social
#LGBTQIA+ #PRIDE #Diversity
#LGBTQIA+ #PRIDE #Diversity
🏳️🌈Our editor @slefkopoulos.bsky.social discussed with @jzylicz.bsky.social about the importance of celebrating Pride, representation in science, and more! Happy Pride!
Read here: rdcu.be/ewfba
bit.ly/3Uc72TO
Read here: rdcu.be/ewfba
bit.ly/3Uc72TO
Coming out is not a one-time event - Nature Cell Biology
June is the month celebrating Pride in the USA and other countries around the world to honour the Stonewall Uprising of 1969, as well as all progress and current strives claiming equal justice for mem...
bit.ly
July 15, 2025 at 4:17 AM
It’s always a bit awkward to write about personal experiences. I tried to touch on what Pride means to me and ended up reflecting on heteronormativity, passing, and allyship. Thank you @slefkopoulos.bsky.social for the great opportunity! @ucph.bsky.social
#LGBTQIA+ #PRIDE #Diversity
#LGBTQIA+ #PRIDE #Diversity
Reposted by AnneWe
💫NEW: @jzylicz.bsky.social & co show that dimethyl α-ketoglutarate enhances the production and functional maturation of human #trophectoderm - like cells from embryonic #StemCells by regulating histone acetyltransferase activity and the pluripotency network.
bit.ly/3EGflmL
bit.ly/3EGflmL
α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells - Nature Cell Biology
Van Nerum et al. show that dimethyl α-ketoglutarate enhances the production and functional maturation of human trophectoderm-like cells from embryonic stem cells by regulating histone acetyltransferas...
bit.ly
May 9, 2025 at 7:54 PM
💫NEW: @jzylicz.bsky.social & co show that dimethyl α-ketoglutarate enhances the production and functional maturation of human #trophectoderm - like cells from embryonic #StemCells by regulating histone acetyltransferase activity and the pluripotency network.
bit.ly/3EGflmL
bit.ly/3EGflmL
Reposted by AnneWe
In a new preprint with @trabelink.bsky.social, T. Moritz & @bonalditiziana.bsky.social, we find that implantation leads to rewiring of the TCA cycle to support histone acetylation turnover and exit from naïve pluripotency. Gr8 work of @elenikafkia.bsky.social D. Pladevall-Morera et al. rb.gy/clk8vm
TCA cycle rewiring underpins implantation and histone acetylation programming
Metabolism has emerged as a key regulator of stem cell differentiation and their epigenomes. This coupling is particularly evident during the exit from naive pluripotency in vitro. However, our unders...
rb.gy
April 29, 2025 at 7:54 AM
In a new preprint with @trabelink.bsky.social, T. Moritz & @bonalditiziana.bsky.social, we find that implantation leads to rewiring of the TCA cycle to support histone acetylation turnover and exit from naïve pluripotency. Gr8 work of @elenikafkia.bsky.social D. Pladevall-Morera et al. rb.gy/clk8vm
Reposted by AnneWe
Can metabolism regulate more than bioenergetics during human development? Our new study says YES! We show that metabolism influences cell fate choice in human naïve pluripotent stem cells, histone acetylation, and trophectoderm maturation. rb.gy/spqr9j
@natcellbio.nature.com
@natcellbio.nature.com
α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells - Nature Cell Biology
Van Nerum et al. show that dimethyl α-ketoglutarate enhances the production and functional maturation of human trophectoderm-like cells from embryonic stem cells by regulating histone acetyltransferas...
rb.gy
April 24, 2025 at 6:57 AM
Can metabolism regulate more than bioenergetics during human development? Our new study says YES! We show that metabolism influences cell fate choice in human naïve pluripotent stem cells, histone acetylation, and trophectoderm maturation. rb.gy/spqr9j
@natcellbio.nature.com
@natcellbio.nature.com
Reposted by AnneWe
Please RT: We are still looking for computational and/or hybrid candidates to join the lab as PhD students. Topics on Alzheimer's Diseases, cell communication and aging. e-mail me if you are interested #joboffer #PhDposition #BCN #scRNAseq
February 18, 2025 at 2:21 PM
Please RT: We are still looking for computational and/or hybrid candidates to join the lab as PhD students. Topics on Alzheimer's Diseases, cell communication and aging. e-mail me if you are interested #joboffer #PhDposition #BCN #scRNAseq
Reposted by AnneWe
Only 2 weeks left to apply! 16 fantastic positions available, also @ucph.bsky.social . For our project remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.
March 3, 2025 at 4:07 PM
Only 2 weeks left to apply! 16 fantastic positions available, also @ucph.bsky.social . For our project remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.
Reposted by AnneWe
We're hiring a motivated PhD student! Join reNEW @ucph.bsky.social & @nucleardn.bsky.social to study how metabolism regulates chromatin & stem cell fate thanks to generous Marie Skłodowska-Curie Fellowship. Remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.
February 7, 2025 at 3:20 PM
We're hiring a motivated PhD student! Join reNEW @ucph.bsky.social & @nucleardn.bsky.social to study how metabolism regulates chromatin & stem cell fate thanks to generous Marie Skłodowska-Curie Fellowship. Remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.
Reposted by AnneWe
I’m very excited about this collaborative project! We managed to significantly scale up and streamline human blastoid generation without the use of feeders. @leeboratory.bsky.social @grazianomartello.bsky.social @pasquelab.bsky.social and Nicolas Rivron @ucph.bsky.social
With pleasure we share our preprint reporting robust and cost-effective expansion of naive human Pluripotent Stem Cells without feeder cells. A fantastic collaborative effort with @leeboratory.bsky.social @jzylicz.bsky.social @pasquelab.bsky.social and Nicolas Rivron.
tinyurl.com/5n6z9rt9
tinyurl.com/5n6z9rt9
January 21, 2025 at 2:29 PM
I’m very excited about this collaborative project! We managed to significantly scale up and streamline human blastoid generation without the use of feeders. @leeboratory.bsky.social @grazianomartello.bsky.social @pasquelab.bsky.social and Nicolas Rivron @ucph.bsky.social
Finally on Bluesky. Running late as usual. (Plagiarizing part of my first tweet from 2015.)
January 23, 2025 at 10:24 AM
Finally on Bluesky. Running late as usual. (Plagiarizing part of my first tweet from 2015.)