Anne-Grete Märtson
@annegretemartson.bsky.social
Assistant Professor | Antiviral Pharmacology | CMV, PK-PD, TDM, dose optimization | Leiden University, the Netherlands.
https://www.universiteitleiden.nl/en/science/drug-research/systems-pharmacology/antiviral-pharmacology Views my own.
https://www.universiteitleiden.nl/en/science/drug-research/systems-pharmacology/antiviral-pharmacology Views my own.
Pinned
Antiviral Pharmacology
The focus of the Antiviral Pharmacology group led by Anne-Grete Märtson is optimizing antiviral therapy for different viral infections by conducting clinical trials and using innovative computational ...
www.universiteitleiden.nl
Hello #bluesky!
In my group we work on optimizing dosing of antivirals using PK-PD modelling, in vitro methods simulating human PK, clinical and TDM studies, currently working with #CMV #ganciclovir #SARSCOV2 #hollowfibre #TDM #viralkinetics #MIPD
www.universiteitleiden.nl/en/science/d...
In my group we work on optimizing dosing of antivirals using PK-PD modelling, in vitro methods simulating human PK, clinical and TDM studies, currently working with #CMV #ganciclovir #SARSCOV2 #hollowfibre #TDM #viralkinetics #MIPD
www.universiteitleiden.nl/en/science/d...
Reposted by Anne-Grete Märtson
✨Wrapping up the 5th Annual Worldwide Precision Dosing seminar 2025 is Assistant Professor Anne-Grete Martson with her talk on 'Precision Dosing in Obesity'!✨
‼️The seminar takes place on Thursday 7 August, so make sure to register before it's too late: bit.ly/3GtrIUb
@annegretemartson.bsky.social
‼️The seminar takes place on Thursday 7 August, so make sure to register before it's too late: bit.ly/3GtrIUb
@annegretemartson.bsky.social
August 4, 2025 at 2:53 AM
✨Wrapping up the 5th Annual Worldwide Precision Dosing seminar 2025 is Assistant Professor Anne-Grete Martson with her talk on 'Precision Dosing in Obesity'!✨
‼️The seminar takes place on Thursday 7 August, so make sure to register before it's too late: bit.ly/3GtrIUb
@annegretemartson.bsky.social
‼️The seminar takes place on Thursday 7 August, so make sure to register before it's too late: bit.ly/3GtrIUb
@annegretemartson.bsky.social
Reposted by Anne-Grete Märtson
Interesting talk by Xuanlin Liu from the groups of @annegretemartson.bsky.social and @cvhasselt.bsky.social at the #LED3Symposium. She talked about her work on characterizing the viral load during Cytomegalovirus (CMV) infections using PCR and TCID50 to build models for efficiency predictions.
June 19, 2025 at 12:36 PM
Interesting talk by Xuanlin Liu from the groups of @annegretemartson.bsky.social and @cvhasselt.bsky.social at the #LED3Symposium. She talked about her work on characterizing the viral load during Cytomegalovirus (CMV) infections using PCR and TCID50 to build models for efficiency predictions.
A better understanding of the PK/PD relationships of antiviral agents used to treat CMV may help to define targets that improve clinical outcomes and reduce the emergence of resistance. Brilliant work by Katie Lynch, it was very nice to work together on this!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
June 10, 2025 at 11:49 AM
A better understanding of the PK/PD relationships of antiviral agents used to treat CMV may help to define targets that improve clinical outcomes and reduce the emergence of resistance. Brilliant work by Katie Lynch, it was very nice to work together on this!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Presenting on ganci TDM, my favourite topic! Great meeting @sidpharm.bsky.social
June 10, 2025 at 11:25 AM
Presenting on ganci TDM, my favourite topic! Great meeting @sidpharm.bsky.social
Loved taking part in this great workshop! Thanks @sidpharm.bsky.social
Check out the highlights from our inaugural PK/PD Workshop hosted by SIDP & the ESCMID PK/PD Study Group of Anti-infectives in historic Madison, Wisconsin!
Thank you to the presenters, attendees, & sponsors for sharing ID/ASP expertise, expanding global networks, & creating wonderful new memories!
Thank you to the presenters, attendees, & sponsors for sharing ID/ASP expertise, expanding global networks, & creating wonderful new memories!
June 10, 2025 at 11:24 AM
Loved taking part in this great workshop! Thanks @sidpharm.bsky.social
Reposted by Anne-Grete Märtson
Obesity alters antibiotic pharmacokinetics. A review of 6113 studies found 128 relevant ones, focusing on dose adjustments for adults (BMI >30 kg/m²) by Dec 30, 2023. 📊💊##idsky
[Review] The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments
Obesity can cause physiological changes resulting in antibiotic pharmacokinetic alterations and suboptimal drug exposures. This systematic review aimed to summarise the available evidence on this topic and provide guidance for dose adjustment of antibiotics in adult (age ≥18 years) patients with obesity (BMI >30 kg/m2). We searched PubMed, Embase, and CENTRAL databases to find relevant studies published between database inception and Dec 30, 2023. We initially identified 6113 studies, which became 4654 studies after duplicate removal, and 128 studies were included in the final review.
www.thelancet.com
May 16, 2025 at 10:30 AM
Obesity alters antibiotic pharmacokinetics. A review of 6113 studies found 128 relevant ones, focusing on dose adjustments for adults (BMI >30 kg/m²) by Dec 30, 2023. 📊💊##idsky
Excited to see people sharing our systematic review, it was a massive effort!
🆕🔥Systematic review and consensus guidelines for dose adjustments with many 🌟 Prof. Jason Roberts & Prof Manjunath P Pai
The pharmacokinetics of antibiotics in patients with obesity. #IDsky #EMIMCC
www.thelancet.com/journals/lan...
The pharmacokinetics of antibiotics in patients with obesity. #IDsky #EMIMCC
www.thelancet.com/journals/lan...
May 16, 2025 at 9:55 AM
Excited to see people sharing our systematic review, it was a massive effort!
Happy to share this systematic review on antibiotic dosing in obesity! Thank you all the co-authors, it was great working together on this! #IDSky #PKPD #ESCMID
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
The pharmacokinetics of antibiotics in patients with obesity: a systematic review and consensus guidelines for dose adjustments
Obesity can cause physiological changes resulting in antibiotic pharmacokinetic alterations and suboptimal drug exposures. This systematic review aime…
www.sciencedirect.com
May 16, 2025 at 9:54 AM
Happy to share this systematic review on antibiotic dosing in obesity! Thank you all the co-authors, it was great working together on this! #IDSky #PKPD #ESCMID
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
My PhD student Lalitya Sudarsono presenting our CMV work at @escmid.bsky.social - Global! Great session on antiviral therapies! #IDSky
April 14, 2025 at 11:45 AM
My PhD student Lalitya Sudarsono presenting our CMV work at @escmid.bsky.social - Global! Great session on antiviral therapies! #IDSky
We had a great time attending the ISAP meeting before @escmid.bsky.social Global 2025, my PhD student Lalitya Sudarsono had a brilliant presentation which led to a presentation award! Looking forward to the next few days in Vienna! #IDSky
April 12, 2025 at 9:53 AM
We had a great time attending the ISAP meeting before @escmid.bsky.social Global 2025, my PhD student Lalitya Sudarsono had a brilliant presentation which led to a presentation award! Looking forward to the next few days in Vienna! #IDSky
Reposted by Anne-Grete Märtson
So glad to celebrate International Day for Women & Girls in Science, especially now.
Diversity, equity & inclusion are principles; you can't end them.
And why would anyone want to play with half a deck of cards?
#WomenInScience #WomenInSTEM #Womeninmedicine #IDSky #ClinMicro @escmid.bsky.social
Diversity, equity & inclusion are principles; you can't end them.
And why would anyone want to play with half a deck of cards?
#WomenInScience #WomenInSTEM #Womeninmedicine #IDSky #ClinMicro @escmid.bsky.social
ESCMID is celebrating the International Day for Women and Girls in Science with two leaders. Giulia De Angelis and Angela Huttner have spoken with us about the importance of this day and you can read here: ow.ly/LGMH50UXoCa
#WomenInScience #WomenInSTEM #IDSky #ClinMicro @angelahuttner.bsky.social
#WomenInScience #WomenInSTEM #IDSky #ClinMicro @angelahuttner.bsky.social
February 11, 2025 at 12:49 PM
So glad to celebrate International Day for Women & Girls in Science, especially now.
Diversity, equity & inclusion are principles; you can't end them.
And why would anyone want to play with half a deck of cards?
#WomenInScience #WomenInSTEM #Womeninmedicine #IDSky #ClinMicro @escmid.bsky.social
Diversity, equity & inclusion are principles; you can't end them.
And why would anyone want to play with half a deck of cards?
#WomenInScience #WomenInSTEM #Womeninmedicine #IDSky #ClinMicro @escmid.bsky.social
Reposted by Anne-Grete Märtson
Had the privilege of doing some of the sound editing on this one
Was a pleasure to spend that time in the company of these amazing women
A little awed by challenges of #climatechange but also energized now
🙏 Nav, @laurajng.bsky.social, @shreya-pedsid.bsky.social
#IDSky #Clinmicro #EpiSky #MedSky
Was a pleasure to spend that time in the company of these amazing women
A little awed by challenges of #climatechange but also energized now
🙏 Nav, @laurajng.bsky.social, @shreya-pedsid.bsky.social
#IDSky #Clinmicro #EpiSky #MedSky
★Just published: #Communicable episode on #climatechange & infections
Host Nav Narayanan explores effects on infections & what we can do w/experts @shreya-pedsid.bsky.social (US) & @laurajng.bsky.social (Germany)
Listen: share.transistor.fm/s/8cc84f7c
#sustainability #AMR #IDSky #MedSky #Clinmicro
Host Nav Narayanan explores effects on infections & what we can do w/experts @shreya-pedsid.bsky.social (US) & @laurajng.bsky.social (Germany)
Listen: share.transistor.fm/s/8cc84f7c
#sustainability #AMR #IDSky #MedSky #Clinmicro
December 16, 2024 at 1:07 PM
Had the privilege of doing some of the sound editing on this one
Was a pleasure to spend that time in the company of these amazing women
A little awed by challenges of #climatechange but also energized now
🙏 Nav, @laurajng.bsky.social, @shreya-pedsid.bsky.social
#IDSky #Clinmicro #EpiSky #MedSky
Was a pleasure to spend that time in the company of these amazing women
A little awed by challenges of #climatechange but also energized now
🙏 Nav, @laurajng.bsky.social, @shreya-pedsid.bsky.social
#IDSky #Clinmicro #EpiSky #MedSky
Reposted by Anne-Grete Märtson
Join us for a joint @idsainfo.bsky.social webinar exploring critical updates on the Marburg Virus outbreak. This session will feature expert insights into the clinical aspects, on-the-ground experiences from outbreak response, and future preparedness strategies.
ow.ly/Egv850UkS59
#IDSky #Clinmicro
ow.ly/Egv850UkS59
#IDSky #Clinmicro
Welcome! You are invited to join a webinar: Global Health Watch: Marburg Virus. After registering, you will receive a confirmation email about joining the webinar.
Join us for a collaborative webinar hosted by IDSA and ESCMID to explore critical updates on the Marburg Virus. This session will feature expert insights into the clinical aspects of the virus, on-the...
ow.ly
December 5, 2024 at 3:00 PM
Join us for a joint @idsainfo.bsky.social webinar exploring critical updates on the Marburg Virus outbreak. This session will feature expert insights into the clinical aspects, on-the-ground experiences from outbreak response, and future preparedness strategies.
ow.ly/Egv850UkS59
#IDSky #Clinmicro
ow.ly/Egv850UkS59
#IDSky #Clinmicro
Excited for this meeting, comiiiing in June 2025! :)
it’s the happiest Thursday because @sidpharm.bsky.social and the @escmid.bsky.social PK PD study group are bringing back ICAAC (in spirit)!!!!
Registration will open next week! The Midwest in the summer is magical - come join us!
sidp.org/page-1543694
#idsky #amssky #pharmsky
Registration will open next week! The Midwest in the summer is magical - come join us!
sidp.org/page-1543694
#idsky #amssky #pharmsky
December 6, 2024 at 1:27 PM
Excited for this meeting, comiiiing in June 2025! :)
Reposted by Anne-Grete Märtson
#IDSky: Assemble!
Now 9 starter packs
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Bonus
#TxID go.bsky.app/95rzmLi
#MedMyco: go.bsky.app/8XGywEx
Now 9 starter packs
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Bonus
#TxID go.bsky.app/95rzmLi
#MedMyco: go.bsky.app/8XGywEx
a man in a red suit and blue tie is holding a piece of paper in his hand .
Alt: Will Ferrell as Ron Burgundy raises a conch to his lips and blows on it
media.tenor.com
November 23, 2024 at 12:47 PM
#IDSky: Assemble!
Now 9 starter packs
1️⃣ go.bsky.app/LnAQjdq
2️⃣ go.bsky.app/JNfSvQT
3️⃣ go.bsky.app/FeogT7o
4️⃣ go.bsky.app/D1zxj4E
5️⃣ go.bsky.app/NgGSPeF
6️⃣ go.bsky.app/22VBL8z
7️⃣ go.bsky.app/Bf7denw
8️⃣ go.bsky.app/jnWLx1
9️⃣ go.bsky.app/9fQaSBa
Bonus
#TxID go.bsky.app/95rzmLi
#MedMyco: go.bsky.app/8XGywEx
Now 9 starter packs
1️⃣ go.bsky.app/LnAQjdq
2️⃣ go.bsky.app/JNfSvQT
3️⃣ go.bsky.app/FeogT7o
4️⃣ go.bsky.app/D1zxj4E
5️⃣ go.bsky.app/NgGSPeF
6️⃣ go.bsky.app/22VBL8z
7️⃣ go.bsky.app/Bf7denw
8️⃣ go.bsky.app/jnWLx1
9️⃣ go.bsky.app/9fQaSBa
Bonus
#TxID go.bsky.app/95rzmLi
#MedMyco: go.bsky.app/8XGywEx
Super excited to share this Breakpoints podcast episode! It was such an nice and also fun discussion! We still need to keep looking into #PKPD of ganciclovir for #CMV and I’m happy to share that we are working on that in my lab in Leiden!
🆕 #Breakpoints Episode: Drs. @annegretemartson.bsky.social, Megan Wimmer, and Evan Clemens join me to discuss all things (Val)ganciclovir!!! #idsky #pharmsky #amssky @sidpharm.bsky.social
🎧 sidp.pinecast.co
🎧 sidp.pinecast.co
November 29, 2024 at 3:56 PM
Reposted by Anne-Grete Märtson
Dengue has resurged globally with larger outbreaks in endemic areas and new cases in nonendemic regions, facilitated by range expansion of vector mosquito populations and climate change, population growth, and urbanization
#idsky #medsky
jamanetwork.com/journals/jam...
#idsky #medsky
jamanetwork.com/journals/jam...
Dengue
This JAMA Insights explores several aspects of dengue virus infection, including epidemiology, diagnosis, and clinical management, following a global resurgence in both endemic and nonendemic regions.
jamanetwork.com
November 28, 2024 at 4:53 AM
Dengue has resurged globally with larger outbreaks in endemic areas and new cases in nonendemic regions, facilitated by range expansion of vector mosquito populations and climate change, population growth, and urbanization
#idsky #medsky
jamanetwork.com/journals/jam...
#idsky #medsky
jamanetwork.com/journals/jam...
Reposted by Anne-Grete Märtson
We made a (far from complete) Starter Pack of Assistant Professors in the Netherlands across all scientific disciplines:
go.bsky.app/AYBAKDp
If you want to be added (or removed), please reply to this post.
And while you are at it, consider joining APNet: ap-net.nl/register/
go.bsky.app/AYBAKDp
If you want to be added (or removed), please reply to this post.
And while you are at it, consider joining APNet: ap-net.nl/register/
November 18, 2024 at 7:59 PM
We made a (far from complete) Starter Pack of Assistant Professors in the Netherlands across all scientific disciplines:
go.bsky.app/AYBAKDp
If you want to be added (or removed), please reply to this post.
And while you are at it, consider joining APNet: ap-net.nl/register/
go.bsky.app/AYBAKDp
If you want to be added (or removed), please reply to this post.
And while you are at it, consider joining APNet: ap-net.nl/register/
Reposted by Anne-Grete Märtson
2024 saw the outbreak of a strain of highly pathogenic avian influenza with intermittent transmission to human.
Excellent 🆕️✨️Review
Avian Influenza: An Overview and Clinical Status #idsky #medsky #H5N1 #HPAI
link.springer.com/article/10.1...
Excellent 🆕️✨️Review
Avian Influenza: An Overview and Clinical Status #idsky #medsky #H5N1 #HPAI
link.springer.com/article/10.1...
Avian Influenza: An Overview and Clinical Status - Current Infectious Disease Reports
Purpose of Review 2024 saw the outbreak of a strain of highly pathogenic avian influenza with intermittent transmission to humans. This review will consider the landscape of avian influenza, the role ...
link.springer.com
November 25, 2024 at 2:03 PM
2024 saw the outbreak of a strain of highly pathogenic avian influenza with intermittent transmission to human.
Excellent 🆕️✨️Review
Avian Influenza: An Overview and Clinical Status #idsky #medsky #H5N1 #HPAI
link.springer.com/article/10.1...
Excellent 🆕️✨️Review
Avian Influenza: An Overview and Clinical Status #idsky #medsky #H5N1 #HPAI
link.springer.com/article/10.1...
This was so fun, thanks for the invitation @erinmccreary.bsky.social 😊
recorded potentially my favorite episode of Breakpoints @sidpharm.bsky.social podcast yet - (val)ganciclovir dosing consult!!
coming to you soon and you'll all get to experience the gift of
@annegretemartson.bsky.social, Evan Clemens, and Megan Wimmer's minds!
#pharmsky #amssky #idsky
coming to you soon and you'll all get to experience the gift of
@annegretemartson.bsky.social, Evan Clemens, and Megan Wimmer's minds!
#pharmsky #amssky #idsky
November 23, 2024 at 7:09 AM
This was so fun, thanks for the invitation @erinmccreary.bsky.social 😊
With the #WAAW2024 special issue of #AAC has been published, insights on model informed drug discovery and development, check it out! www.sciencedirect.com/special-issu...
International Journal of Antimicrobial Agents | Model Informed Drug Discovery and Development (MID3) for Antimicrobials | ScienceDirect.com by ElsevierScienceDirect
Read the latest articles of International Journal of Antimicrobial Agents at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
November 21, 2024 at 11:01 AM
With the #WAAW2024 special issue of #AAC has been published, insights on model informed drug discovery and development, check it out! www.sciencedirect.com/special-issu...
Reposted by Anne-Grete Märtson
The demonstration against the cuts to higher education has been rescheduled to Monday, November 25th, at 13:00 at the Malieveld in Den Haag. Several members of our board will be present. Join to also make your voice heard.
www.aob.nl/actueel/camp...
www.aob.nl/actueel/camp...
kabinetsloopthogeronderwijs | De Algemene Onderwijsbond
www.aob.nl
November 21, 2024 at 8:42 AM
The demonstration against the cuts to higher education has been rescheduled to Monday, November 25th, at 13:00 at the Malieveld in Den Haag. Several members of our board will be present. Join to also make your voice heard.
www.aob.nl/actueel/camp...
www.aob.nl/actueel/camp...
Reposted by Anne-Grete Märtson
Super excited to be at Pasteur next Friday :)
November 21, 2024 at 9:12 AM
Super excited to be at Pasteur next Friday :)
Reposted by Anne-Grete Märtson
Current and future strategies for the prevention and treatment of cytomegalovirus infections in transplantation
Heldman, Boeckh, Limaye
IDSky
academic.oup.com/cid/advance-...
Heldman, Boeckh, Limaye
IDSky
academic.oup.com/cid/advance-...
academic.oup.com
November 4, 2024 at 2:23 PM
Current and future strategies for the prevention and treatment of cytomegalovirus infections in transplantation
Heldman, Boeckh, Limaye
IDSky
academic.oup.com/cid/advance-...
Heldman, Boeckh, Limaye
IDSky
academic.oup.com/cid/advance-...