Ankur Gupta-Wright
ankurgw.bsky.social
Ankur Gupta-Wright
@ankurgw.bsky.social
Infectious Diseases Consultant and Academic
TB, HIV, respiratory infections, AMR, diagnostics
Reposted by Ankur Gupta-Wright
🎥 The first BreathForDx webinar is now online!
We discuss community engagement and early steps in breath-based diagnostics for infectious diseases.

👉 Watch it here: breathfordx.org/project-reso...

#BreathForDx #GlobalHealth #Diagnostics #EUresearch #Webinar #CommunityEngagement
Project webinar - Breath For DX
PROJECT RESOURCES
breathfordx.org
July 11, 2025 at 9:44 AM
Reposted by Ankur Gupta-Wright
Prof Lord Ara Darzi, writing in @observeruk.bsky.social, warns that axing the Fleming Fund, Britain’s landmark antimicrobial resistance initiative ( #AMR ), would be a deadly retreat.

With 5 million annual global deaths, the stakes couldn’t be higher.
observer.co.uk/news/nationa...
‘Bacteria knows no borders. The UK and Fleming Fund must ...
The planned dismantling of the world’s largest fund to fight antimicrobial resistance could contribute to millions of deaths worldwide
observer.co.uk
July 22, 2025 at 1:40 PM
Reposted by Ankur Gupta-Wright
🌬️ Discover the Power of Breath in Diagnostics!
Over the past months, we’ve been working across Europe and South Africa to develop breath-based tools for diagnosing respiratory infections — and now you can see what we’ve been up to.

📺 Watch the full video here:
👉 breathfordx.org/project-reso...
Project video - Breath For DX
PROJECT RESOURCES
breathfordx.org
June 25, 2025 at 1:26 PM
Despite molecular diagnostics for TB, 40% of patients are still diagnosed clinically. We also found a 50% higher mortality in this group, suggesting overtreatment/missing conditions other than TB. www.sciencedirect.com/science/arti... @imperialinfect.bsky.social @uniheidelberg.bsky.social
Clinically diagnosed tuberculosis and mortality in high burden settings: a systematic review and meta-analysis
Clinical diagnosis of tuberculosis (TB), referring to diagnosis without bacteriological confirmation, is common and may affect an individuals’ outcome…
www.sciencedirect.com
May 23, 2025 at 12:42 PM
Excited to be presenting an outline of our @ec.europa.eu funded B-Path programme to advance breath-based diagnostics for respiratory infections at PREPARE-EU @uniheidelberg.bsky.social @cdenki.bsky.social @digbywarner.bsky.social
Pandemic Preparedness Spring School: Few more days to submit your work to PREPARE-EU!
May 19, 2025 at 9:02 PM
Reposted by Ankur Gupta-Wright
BreathForDx is a EU-funded research initiative aimed at improving early diagnosis of respiratory infections through exhaled breath aerosol (XBA) sampling. It combines non-invasive diagnostic innovation with clinical research to detect tuberculosis and viral infections.

breathfordx.org
Breath For DX - Making every breath count for diagnosis
Making every breath count for diagnosis. Establishing Exhaled Breath Aerosol (XBA) sampling for diagnosis and screening of respiratory infections.
breathfordx.org
April 30, 2025 at 1:16 PM
Reposted by Ankur Gupta-Wright
Enhanced tuberculosis diagnosis with computer-aided chest X-ray and urine LAM in adults with HIV admitted to hospital (CASTLE study): A cluster randomised trial

#IDSky
Enhanced tuberculosis diagnosis with computer-aided chest X-ray and urine LAM in adults with HIV admitted to hospital (CASTLE study): A cluster randomised trial
People with human immunodeficiency virus (PHIV) admitted to the hospital have high mortality, with tuberculosis (TB) being the major cause of death. Systematic use of new TB diagnostics could improve TB diagnosis and might improve outcomes.
doi.org
March 27, 2025 at 7:08 PM
Great to see utility of rapid TB dx being demonstrated tinyurl.com/jvfka44d. Graet to be part of ongoing development of dx for drug resistant TB with R2D2 TB Network @cdenki.bsky.social and teams in Georgia/Philippines/SA.
Programmatic Diagnostic Accuracy and Clinical Utility of Xpert MTB/XDR in Patients With Rifampicin-Resistant Tuberculosis in Georgia
AbstractBackground. Xpert MTB/XDR (Cepheid) is recommended by the World Health Organization for drug susceptibility testing in patients with tuberculosis,
tinyurl.com
March 3, 2025 at 12:07 PM
Reposted by Ankur Gupta-Wright
Tuberculosis: a biosocial problem that requires biosocial solutions

www.thelancet.com/journals/lan...
December 4, 2024 at 8:43 PM
Time to stop funding/doing more vit D in TB trials?
Regarding the role of vitamin D in tuberculosis treatment, there were no significant differences between the vitamin D group and the control group in terms of sputum smear conversion rate, sputum culture conversion rate, and time to sputum culture conversion #idsky #medsky #AMSsky #tbsky
🆕️✨️Meta-analysis of randomized controlled trials
The role of vitamin D in the prevention and treatment of tuberculosis #idsky #medsky #AMSsky #tbsky
link.springer.com/article/10.1...
November 30, 2024 at 8:11 PM
Reposted by Ankur Gupta-Wright
Are Bacteria Sensitive or Susceptible? A Micro-Comic Strip 😂
S: Susceptibile or Sensitive ?
Which one you use?
Me : Susceptible
#idsky #microsky #medsky
journals.asm.org/doi/10.1128/...
November 29, 2024 at 10:10 PM
Reposted by Ankur Gupta-Wright
Footprints in Kenya ‘show distant relatives of modern humans coexisted’
Footprints in Kenya ‘show distant relatives of modern humans coexisted’
Researchers say fossilised marks were apparently made in same place within days of each other about 1.5m years ago About 1.5m years ago a big-toothed cousin of prehistoric humans walked quickly along a lakeside in Kenya, footprints marking the muddy…
www.theguardian.com
November 28, 2024 at 7:10 PM
Reposted by Ankur Gupta-Wright
A systematic review showed that there is still scant evidence to confidently confirm the benefit-risk of antibiotics use in preventing subsequent GAS #idsky #medsky
November 26, 2024 at 8:23 PM
Reposted by Ankur Gupta-Wright
New β-lactams allow treating Pseudomonas that were untreatable, but… are they better than previous options?

This meta-analysis of RCTs shows they are not superior to prior alternatives when available: www.ajicjournal.org/article/S019...

👐🏻 Use them wisely, make them last
#PsWatch #AMSsky #IDsky
Effectiveness of novel β-lactams for Pseudomonas aeruginosa infection: A systematic review and meta-analysis
Novel β-lactams have in vitro activity against Pseudomonas aeruginosa (PA), but their clinical performances and the selection criteria for practical use are still not clear. We aimed to evaluate the e...
www.ajicjournal.org
November 24, 2024 at 3:19 PM
Reposted by Ankur Gupta-Wright
🚨New Publication🚨 led by @biancasossen.bsky.social

In a 7 country study, we found that urine Xpert Ultra was as sensitive & more specific than AlereLAM for #TB diagnosis in people with #HIV

Also predicts mortality and allows detection of Rif resistance.

authors.elsevier.com/sd/article/S...

🧪🛟
November 21, 2024 at 7:57 AM
Reposted by Ankur Gupta-Wright
🔥Everyone's favorite #shorterisbetter table is updated🔥
"BALANCE is now published,
so the table is now updated!
GNB bacteremia is now listed as Bacteremia(non S.aureus)
Neary 5,000 patients have now been randomized to 1 vs. 2 Constantine Units for non S. aureus bacteremia " Dr.Spellberg #idsky
November 20, 2024 at 10:18 PM
Reposted by Ankur Gupta-Wright
Glad my first post on bsky is to highlight a review just out today by our group - discussing how digital health tech can optimise AMU. Let's ensure we build in equitable access and global solutions

www.thelancet.com/journals/lan...
Using digital health technologies to optimise antimicrobial use globally
Digital health technology (DHT) describes tools and devices that generate or process health data. The application of DHTs could improve the diagnosis, treatment, and surveillance of bacterial infectio...
www.thelancet.com
November 15, 2024 at 8:47 AM