Ángel Sánchez Illana
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angelsi.bsky.social
Ángel Sánchez Illana
@angelsi.bsky.social
PhD in Chemistry. Chemometrics, vibrational spec, lipidomics and amateur astronomy. Juan de la Cierva fellow at Universitat de València (Spain).
Reposted by Ángel Sánchez Illana
Esta es la foto ganadora de la del concurso "Fotógrafo del año 2025" convocado por la Royal Meteorological Society de Reino Unido. Su autor es el chino Geshuang Chen.
November 10, 2025 at 8:27 PM
Reposted by Ángel Sánchez Illana
🔭 Comet Lemmon Brightens

Image Credit & Copyright: Victor Sabet & Julien De Winter

apod.nasa.gov/apod/ap25093...
September 30, 2025 at 8:00 AM
Reposted by Ángel Sánchez Illana
For the first time, kidney health is in the draft UN Political Declaration, a milestone to celebrate!

Next week, ISN President Marcello Tonelli and the ISN team will be in New York for #HLM4, working with global leaders to turn commitments into action 🌍💪

👉 Follow the updates from #UNGA80!

#UNGA
September 19, 2025 at 1:26 PM
Such a landmark contribution. Congratulations!
I am very proud of the final outcome of this project, mainly driven by Corinna Brungs and supported by numerous labs who donated compounds for analysis.
The @pluskal-lab.org is helping colleagues around the world identify unknown compounds.

A #research article about their vast #massspec library has been published in @natmethods.nature.com with Corinna Brungs & @robinschmidt.bsky.social as the first two authors.

See more ► www.uochb.cz/en/news/732
September 16, 2025 at 8:40 AM
Por favor.
🚭 Prohíbe fumar en terrazas

🚭 Equipara cigarrillos electrónicos y tabaco convencional

🚭Veta por primera vez el consumo, y no solo la venta, en menores.

Así es el anteproyecto de reforma de la ley del tabaco aprobado hoy en el Consejo de Ministros
El proyecto de ley del tabaco veta el humo en las terrazas, prohíbe fumar a los menores y limita el vapeo
La norma tendrá que ser debatida en el Congreso, donde Sanidad quiere incluir el empaquetado genérico, que se ha caído del texto inicial
elpais.com
September 9, 2025 at 8:19 PM
Reposted by Ángel Sánchez Illana
📢‼️ Salimos a las calles para pedir que se cumpla el #PactoXLaCiencia
🕛🏛️ El 28 de septiembre a las 12:00 en el Congreso de los Diputados (calle Zorrilla)
@CienciaGob @DianaMorantR @CigudosaJuan debe cumplir YA lo firmado #SinCienciaNoHayFuturo
👇🏼🧵
September 8, 2025 at 8:14 AM
Reposted by Ángel Sánchez Illana
Some very peculiar fragmentation at the opposite of classical deoxyPGJ2. There is even some deoxyPGJ2 attempts for QCxMS demonstrating it's usefulness, sometimes.. there is another potential mechanism in the SI @grimmelab.bsky.social can wait to try it's second version . @jogorges.bsky.social
August 23, 2025 at 10:20 AM
Reposted by Ángel Sánchez Illana
Here is our last paper, a novel deoxy like prostaglandin from DHA from Pavlíčková chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
total synthesis, high resolution msms and its simulation by QCxMS and finally a little bit of molecular networking. Enjoy. We are at our best here. Chemist 2.0😅
Beyond Neuroprostanes: Total Synthesis and Epilipidomic Studies of a Novel Cyclopentenone Metabolite of Docosahexaenoic Acid
Neuroprostanes are bioactive oxylipins from docosahexaenoic acid oxidation, serving as oxidative stress biomarkers. In this work, the enantioselective synthesis of 4-A4-NeuroP-1,4-lactone and 4-deoxy...
chemistry-europe.onlinelibrary.wiley.com
August 23, 2025 at 7:51 AM
Reposted by Ángel Sánchez Illana
Estudio publicado en The Lancet sobre los efectos del calor en 2019.
Ese año murieron 345.000 personas mayores de 65 años por el calor. El uso de aire acondicionado hubiese evitado 195.000 muertes.
Pero aquí hay gente diciendo q el aire acondicionado es maligno.
August 17, 2025 at 1:52 PM
Reposted by Ángel Sánchez Illana
🔭 Zodiacal Road

Image Credit & Copyright: Ruslan Merzlyakov (astrorms)

apod.nasa.gov/apod/ap25081...
August 10, 2025 at 8:00 AM
Reposted by Ángel Sánchez Illana
☀ Que las olas de calor se alarguen tanto ha sido muy extraordinario en el pasado, pero que cada vez lo sean menos resulta una señal inequívoca del cambio climático. Te contamos cómo han ido cambiando ⬇
Así han cambiado las olas de calor: son cada vez más frecuentes, duraderas e intensas
Según la Aemet, los españoles de final de siglo vivirán entre 60 y 77 días al año de estos fenómenos de temperaturas extremas si no se toman medidas decididas contra el cambio climático
elpais.com
August 7, 2025 at 6:35 AM
Reposted by Ángel Sánchez Illana
Las autonomías autorizan cada vez más plazas a la universidad privada mientras la pública es incapaz de acoger a miles de alumnos. “Las privadas proponen siempre muchas plazas, más de las que van a llenar, porque marcan territorio para el futuro" social.elpais.com/h6g1s6
Las autonomías autorizan cada vez más plazas a la universidad privada mientras la pública es incapaz de acoger a miles de alumnos
El reparto provisional de puestos para septiembre refleja la voluntad de engordar los centros de pago, que acumulan el 35% de la oferta de carreras aunque matriculan a un 25% de los estudiantes
social.elpais.com
July 29, 2025 at 6:10 AM
Reposted by Ángel Sánchez Illana
mzQuality: An Open-Source Software Tool for Quality Monitoring and Reporting of Targeted Mass Spectrometry Measurements #JASMS pubs.acs.org/doi/10.1021/...
pubs.acs.org
July 26, 2025 at 4:16 AM
Reposted by Ángel Sánchez Illana
"¿Señor Montoro, es usted el Ministro de Hacienda o el Ministro de los Defraudadores?"

Cayo Lara ya en 2013 advirtió que trabajaba para los capitalistas. El PP de Feijóo es el mismo de ayer, de hoy y de siempre.
July 17, 2025 at 3:34 PM
Reposted by Ángel Sánchez Illana
Es difícil que una persona al azar no se haya beneficiado del descomunal trabajo del prácticamente desconocido científico Pedro Cuatrecasas. El investigador participó en el desarrollo de unos 40 medicamentos, como el aciclovir, el sumatriptán y la atorvastatina
Pedro Cuatrecasas, el español desconocido que pudo ganar dos Premios Nobel
El científico, fallecido a los 88 años en Estados Unidos, transformó la vida de millones de personas tras participar en el desarrollo de 40 nuevos medicamentos
elpais.com
July 13, 2025 at 11:34 AM
Reposted by Ángel Sánchez Illana
🔭 Terminator Moon: A Moonscape of Shadows

Image Credit & Copyright: Rich Addis

apod.nasa.gov/apod/ap25042...
April 22, 2025 at 8:00 AM
Reposted by Ángel Sánchez Illana
Os presento mi primer sketch sobre discapacidad.

Mil gracias a @davidpareja.com por haberme ayudado un montón a hacerlo. Me lo he pasado genial y el resultado me parece maravilloso. ❤️
March 24, 2025 at 4:08 PM
Reposted by Ángel Sánchez Illana
Decades from now, the Covid-19 pandemic will be visible in the historical data of nearly anything measurable today. Here’s an incomplete collection of charts that capture that break — across the economy, health care, education, work, family life and more.
30 Charts That Show How Everything Changed in March 2020
It can be easy to forget, or look away from, the pain and disruption of the pandemic. The numbers will be there to remind us.
www.nytimes.com
March 10, 2025 at 7:24 AM
Reposted by Ángel Sánchez Illana
hey any chemists with synthetic experience in making the compound 1.
like a real protocol not that shabby reference.
our yield is just pointless.
How do you make you methycyclopropene for click chemistry if by this way? #click
thank you
March 6, 2025 at 3:35 PM
I always feel that RT and LC information are often underutilized in metabolomics, so it's really exciting to see them implemented in networking and clustering! Really nice work to explore and learn from!
I am excited to share this new paper out in JPR - "MS-RT: A Method for Evaluating MS/MS Clustering Performance for Metabolomics Data." This work introduces the MS-RT method to assess MS/MS clustering accuracy on metabolomics data.

doi.org/10.1021/acs....
MS-RT: A Method for Evaluating MS/MS Clustering Performance for Metabolomics Data
The clustering of tandem mass spectra (MS/MS) is a crucial computational step to deduplicate repeated acquisitions in data-dependent experiments. This technique is essential in untargeted metabolomics, particularly with high-throughput mass spectrometers capable of generating hundreds of MS/MS spectra per second. Despite advancements in MS/MS clustering algorithms in proteomics, their performance in metabolomics has not been extensively evaluated due to the lack of database search tools with false discovery rate control for molecule identification. To bridge this gap, this study introduces the MS1-retention time (MS-RT) method to assess MS/MS clustering performance in metabolomics data sets. Here, we validate MS-RT by comparing MS-RT to established proteomics clustering evaluation approaches that utilize database search identifications. Additionally, we evaluate the performance of several MS/MS clustering tools on metabolomics data sets, highlighting their advantages and drawbacks. This MS-RT method and the MS/MS clustering tool benchmarking will provide valuable real world practical recommendations for tools and set the stage for future advancements in metabolomics MS/MS clustering.
doi.org
March 5, 2025 at 5:45 PM
Reposted by Ángel Sánchez Illana
Discovery of metabolites prevails amid in-source fragmentation #NatMetab www.nature.com/articles/s42...
Discovery of metabolites prevails amid in-source fragmentation - Nature Metabolism
Nature Metabolism - Discovery of metabolites prevails amid in-source fragmentation
www.nature.com
March 1, 2025 at 8:12 PM
Such an amazing achievement! Huge congrats to @pieterdorrestein.bsky.social ! From now on, every time I use mzmine or FBMN in GNPS, I’ll remember I'm working with a cutting-edge space technology 🚀. Truly incredible!
www.cell.com/cell/fulltex...
The International Space Station has a unique and extreme microbial and chemical environment driven by use patterns
With long-term space travel and extraterrestrial habitation becoming feasible, understanding how space environmental exposures, microbial communities, and molecular profiles differ from Earth is cruci...
www.cell.com
February 28, 2025 at 8:07 AM
See our collaboration 🇫🇷 (Montpellier) 🇨🇳 (Shanghai) 🇪🇸 (Valencia)! We've annotated a DHA-derived oxylipin as an interferent in PFAS analysis. Read the real expert @galanojeanmarie.bsky.social about these trioxilins! 👇 Now, challenge accepted: keep working to confirm their abundance and distribution!
February 19, 2025 at 8:03 PM
Reposted by Ángel Sánchez Illana
What is the link between PFAS type contaminant and oxylipins? None?
Well mass spectrometry low resolution identification can always messed up somehow, and revealed to the lipid community the long forgotten space left by the Trioxilins… A thread
doi.org/10.1021/acs....
#epilipid #massspec #oxylipins
Annotating DHA Metabolites Interfering with the Quantification of Emerging Perfluoroalkyl Ether Carboxylic Acids
Quantitative analyses of per- and polyfluoroalkyl substances (PFAS) commonly rely on low-resolution targeted tandem mass spectrometry (MS/MS) due to its high sensitivity and relatively low operational...
doi.org
February 18, 2025 at 5:32 PM
Reposted by Ángel Sánchez Illana
🔭 Christmas Tree Aurora

Image Credit & Copyright: Jingyi Zhang

apod.nasa.gov/apod/ap24122...
December 23, 2024 at 8:00 AM