A Naqvi
@anaqvi.bsky.social
New York ripened, Philly hardened. First gen. Principal Bfx Scientist (PhD) at @ChildrensPhila and http://d3b.center. Human rights. Cancer genomics. Tweets are my own. #openscience
Reposted by A Naqvi
We understand that the government shutdown is impacting vital support of SNAP and WIC effective 11/1 for our families and community members. Access to healthy food is crucial. If you need assistance, check out local resources here: ms.spr.ly/63328tEcIm.
October 31, 2025 at 5:21 PM
We understand that the government shutdown is impacting vital support of SNAP and WIC effective 11/1 for our families and community members. Access to healthy food is crucial. If you need assistance, check out local resources here: ms.spr.ly/63328tEcIm.
Reposted by A Naqvi
Scientists are designing mRNA vaccines to produce virus-like nanoparticles, which should lead to a more robust immune response with even fewer side effects than either of these immunisation approaches on their own
Why the next generation of mRNA vaccines is set to be even better
www.newscientist.com
October 22, 2025 at 3:26 AM
Scientists are designing mRNA vaccines to produce virus-like nanoparticles, which should lead to a more robust immune response with even fewer side effects than either of these immunisation approaches on their own
I try really hard to not gate keep data, but if you don’t understand basic formats and conversions, I’m sorry that is on you 🙃
October 7, 2025 at 2:33 PM
I try really hard to not gate keep data, but if you don’t understand basic formats and conversions, I’m sorry that is on you 🙃
Reposted by A Naqvi
New hope for kids with brain tumors! Read about the latest #CBTN breakthrough. https://monkeylink.co/628011 #BrainTumorResearch
August 19, 2025 at 4:06 PM
New hope for kids with brain tumors! Read about the latest #CBTN breakthrough. https://monkeylink.co/628011 #BrainTumorResearch
Reposted by A Naqvi
The US health secretary is cutting funding for mRNA vaccines because he claims they are less effective than other types – but that is not what the evidence shows
What you need to know about mRNA vaccines in light of RFK's claims
www.newscientist.com
August 11, 2025 at 7:26 PM
The US health secretary is cutting funding for mRNA vaccines because he claims they are less effective than other types – but that is not what the evidence shows
Our paper is finally out there! And yes, we discovered the role of microexons in immunotherapy targeting in high-grade gliomas! www.cell.com/cell-reports...
NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas
Aberrant splicing of microexons yields non-canonical surface receptors, such as the
neuronal cell adhesion molecule (NRCAM) lacking amino acids encoded by exons 5 and
19. Sehgal et al. show that Δex5Δ...
www.cell.com
August 8, 2025 at 3:02 PM
Our paper is finally out there! And yes, we discovered the role of microexons in immunotherapy targeting in high-grade gliomas! www.cell.com/cell-reports...
Reposted by A Naqvi
Cancelling $500 million in vaccine research is exactly what a virus would do if it ran the Department of Health and Human Services.
August 6, 2025 at 5:22 PM
Cancelling $500 million in vaccine research is exactly what a virus would do if it ran the Department of Health and Human Services.
Reposted by A Naqvi
We'll have to do a "March for mRNA" 🤦♂️
RFK Jr and HHS just ended all US supported mRNA vaccine development
www.hhs.gov/press-room/h...
www.hhs.gov/press-room/h...
www.hhs.gov
August 6, 2025 at 12:53 AM
We'll have to do a "March for mRNA" 🤦♂️
Wow!!The normalization of Islamophobia across our society and institutions is everywhere, really unavoidable and on full display, as we start the process to elect NYC’s first Muslim mayor.
June 27, 2025 at 12:34 PM
Wow!!The normalization of Islamophobia across our society and institutions is everywhere, really unavoidable and on full display, as we start the process to elect NYC’s first Muslim mayor.
let’s go!
🧵 NYC: Zohran Mamdani is an extraordinary political talent and he CAN win this.
What a signal that would send to the country and to the world.
If you have been on the fence, this is the moment to go all in.
What a signal that would send to the country and to the world.
If you have been on the fence, this is the moment to go all in.
Zohran is up. Keep going.
June 12, 2025 at 6:02 AM
let’s go!
Reposted by A Naqvi
Connor’s strength was eternal, and his love for life knew no bounds. He and #RCDFoundation show what true fortitude looks like. Connor had strength—now we honor it.
#ThisIsWhy #BrainTumorAwarenessMonth
#ThisIsWhy #BrainTumorAwarenessMonth
May 23, 2025 at 3:50 PM
Connor’s strength was eternal, and his love for life knew no bounds. He and #RCDFoundation show what true fortitude looks like. Connor had strength—now we honor it.
#ThisIsWhy #BrainTumorAwarenessMonth
#ThisIsWhy #BrainTumorAwarenessMonth
Reposted by A Naqvi
CHOP & @pennmedicine.bsky.social have delivered the first-ever personalized gene editing therapy for a patient with CPS1 deficiency, marking a major milestone in the application of CRISPR-based treatments.
Learn more about KJ & the future of personalized medicine: www.chop.edu/news/worlds-....
Learn more about KJ & the future of personalized medicine: www.chop.edu/news/worlds-....
May 15, 2025 at 5:04 PM
CHOP & @pennmedicine.bsky.social have delivered the first-ever personalized gene editing therapy for a patient with CPS1 deficiency, marking a major milestone in the application of CRISPR-based treatments.
Learn more about KJ & the future of personalized medicine: www.chop.edu/news/worlds-....
Learn more about KJ & the future of personalized medicine: www.chop.edu/news/worlds-....
Reposted by A Naqvi
The discovery of the cosmic acceleration problem truly inspired me as a teenage physics nerd. Recent, related revelations about dark energy will hopefully capture the interest of today’s young science geeks, says Chanda Prescod-Weinstein
How dark energy findings may inspire a new generation of physics nerds
The discovery of the cosmic acceleration problem truly inspired me as a teenage physics nerd. Recent, related revelations about dark energy will hopefully capture the interest of today’s young science geeks, says Chanda Prescod-Weinstein
www.newscientist.com
May 15, 2025 at 6:58 PM
The discovery of the cosmic acceleration problem truly inspired me as a teenage physics nerd. Recent, related revelations about dark energy will hopefully capture the interest of today’s young science geeks, says Chanda Prescod-Weinstein
Reposted by A Naqvi
We are often warned of the consequences of knowing too much, but even when scientific ideas have the potential to be harmful we should still seek to understand them
Science is a Pandora's box – but we should open it anyway
We are often warned of the consequences of knowing too much, but even when scientific ideas have the potential to be harmful we should still seek to understand them
www.newscientist.com
May 11, 2025 at 4:39 PM
We are often warned of the consequences of knowing too much, but even when scientific ideas have the potential to be harmful we should still seek to understand them
Reposted by A Naqvi
Draft Trump budget proposes a $20 billion NIH budget cut in 2026 and a sweeping consolidation
Trump budget draft proposes NIH consolidation and 40% spending cut
Draft Trump budget proposes a $20 billion NIH budget cut in 2026 and a sweeping consolidation
buff.ly
April 17, 2025 at 2:45 AM
Draft Trump budget proposes a $20 billion NIH budget cut in 2026 and a sweeping consolidation
Reposted by A Naqvi
The Genetics research community has a problem. Most recent articles do not consider #splicing/isoforms.
Here, we analyze how important this opportunity gap is - and spoiler warning - we find it is essential for both analysis of common and rare variants
More info👇
www.medrxiv.org/content/10.1...
Here, we analyze how important this opportunity gap is - and spoiler warning - we find it is essential for both analysis of common and rare variants
More info👇
www.medrxiv.org/content/10.1...
Beyond the Gene in Genetics: How Isoform-Resolved Analysis Empowers the Study of Both Common and Rare Genetic Variation
Genetics is rapidly deepening our understanding of human health and disease by investigating common and rare genetic variants and their influence on gene expression1,2. Alternative splicing is a molec...
www.medrxiv.org
April 2, 2025 at 7:45 AM
The Genetics research community has a problem. Most recent articles do not consider #splicing/isoforms.
Here, we analyze how important this opportunity gap is - and spoiler warning - we find it is essential for both analysis of common and rare variants
More info👇
www.medrxiv.org/content/10.1...
Here, we analyze how important this opportunity gap is - and spoiler warning - we find it is essential for both analysis of common and rare variants
More info👇
www.medrxiv.org/content/10.1...
Reposted by A Naqvi
It's not just COVID. mRNA vaccines tech is yielding incredible early results for treating cancer. We need more, not less science!
"...six out of eight who responded to the vaccine in the first study did not have their cancer return more than 3 years later"
www.sciencefriday.com/segments/pan...
"...six out of eight who responded to the vaccine in the first study did not have their cancer return more than 3 years later"
www.sciencefriday.com/segments/pan...
March 17, 2025 at 8:49 PM
It's not just COVID. mRNA vaccines tech is yielding incredible early results for treating cancer. We need more, not less science!
"...six out of eight who responded to the vaccine in the first study did not have their cancer return more than 3 years later"
www.sciencefriday.com/segments/pan...
"...six out of eight who responded to the vaccine in the first study did not have their cancer return more than 3 years later"
www.sciencefriday.com/segments/pan...
Reposted by A Naqvi
Bsky vs Twitter engagement difference now 50-fold...
March 11, 2025 at 4:18 PM
Bsky vs Twitter engagement difference now 50-fold...
Reposted by A Naqvi
Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives.
An assault on science anywhere is an assault on science everywhere; the global community must unite
🧪
www.nature.com/articles/d41...
An assault on science anywhere is an assault on science everywhere; the global community must unite
🧪
www.nature.com/articles/d41...
Trump 2.0: an assault on science anywhere is an assault on science everywhere
US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.
www.nature.com
February 25, 2025 at 7:48 PM
Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives.
An assault on science anywhere is an assault on science everywhere; the global community must unite
🧪
www.nature.com/articles/d41...
An assault on science anywhere is an assault on science everywhere; the global community must unite
🧪
www.nature.com/articles/d41...
Honest question: is something “reproducible” if it requires exorbitant amount of $$$ to reproduce (ie inaccessible)?
February 19, 2025 at 3:30 PM
Honest question: is something “reproducible” if it requires exorbitant amount of $$$ to reproduce (ie inaccessible)?
We did it! Go Birds 🦅🦅🦅
February 10, 2025 at 6:27 PM
We did it! Go Birds 🦅🦅🦅
Reposted by A Naqvi
#BREAKING - 22 states sue to block Trump administration cuts to NIH research payments
22 states sue to block Trump administration cuts to NIH research payments
Attorneys general sued the Trump administration to block a NIH decision that would slash grant payments for research overhead
buff.ly
February 10, 2025 at 5:26 PM
#BREAKING - 22 states sue to block Trump administration cuts to NIH research payments