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Analytical Methods
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The home of discoveries in the applied analytical and bioanalytical sciences, for the benefit of society and humanity.

Published by @rsc.org 🌐 Website: rsc.li/analyticalmethods

On the front cover of issue 43 of Analytical Methods:
A liquid crystal-based sensor for real-time, selective, and visual detection of vanillin over coumarin in food samples.
Sachin Kumar Singh et al.
pubs.rsc.org/en/content/a...
November 10, 2025 at 8:46 AM
Available to read now via #OpenAccess:
pubs.rsc.org/en/Content/A...
Detection of anticoagulant rodenticides by direct analysis in real time time-of-flight mass spectrometry: novel screening techniques and rapid semi-quantitative determination
Dayue Shang et al
@lifeatbcit.bsky.social @sfu.ca
November 5, 2025 at 10:21 AM
On the front cover of issue 42 of Analytical Methods:
Simple preparation of an Au nanoparticle dispersed substrate by arc plasma deposition and its application in bio-sensing using LSPR.
Takeshi Ito et al.
pubs.rsc.org/en/content/a...
November 3, 2025 at 9:12 AM
📢 Welcome our newest Analytical Methods Advisory Board members: Dr. Stefano Cinti from the University of Naples, IT and Dr. Bob Pirok from the University of Amsterdam, NL.

Please join us in welcoming Stefano and Bob to the Analytical Methods AB!🙌

#analyticalchemistry #biosensors #chromatography
October 28, 2025 at 10:04 AM
On the front cover of issue 41 of Analytical Methods:
Nanoscale mapping of nucleolin–aptamer interactions on lung cancer cells reveals binding affinity hierarchy and spatial heterogeneity.
Weidong Zhao, Feng Jiang et al.
pubs.rsc.org/en/content/a...
October 27, 2025 at 9:37 AM
Reposted by Analytical Methods
Desorption electrospray ionization mass spectrometry: advances in instrumentation, high-throughput analysis, and imaging applications pubs.rsc.org/en/cont...

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#proteomics #prot-paper
October 23, 2025 at 2:01 PM
Reposted by Analytical Methods
(RSC A Meth) Desorption electrospray ionization mass spectrometry: advances in instrumentation, high-throughput analysis, and imaging applications: Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01323B, Tutorial ReviewKhaled W. Omari
DESI-MS is an ambient ionization, rapid, and… #MassSpecRSS
Desorption electrospray ionization mass spectrometry: advances in instrumentation, high-throughput analysis, and imaging applications
Anal. Methods, 2025, Advance Article DOI: 10.1039/D5AY01323B, Tutorial ReviewKhaled W. Omari DESI-MS is an ambient ionization, rapid, and high-throughput molecular analysis directly from surfaces. Recent advancements enhance its performance in imaging and diagnostics. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
dlvr.it
October 22, 2025 at 2:07 AM
On the front cover of issue 40 of Analytical Methods:
Considerations for deconvolution of oligonucleotide mass spectra in quality control.
Michael Rühl.
pubs.rsc.org/en/content/a...
October 20, 2025 at 8:16 AM
Available to read now via #OpenAccess
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Demonstrating the application of a liquid chromatography-mass spectrometry method for the determination of phthalate diesters in complex solid and liquid environmental samples
Fiona Regan et al
@dublincityuni.bsky.social
October 17, 2025 at 7:33 AM
On the front cover of issue 39 of Analytical Methods:
A protein-nanoparticle conjugate platform for simplified and sensitive protease activity assays.
Masafumi Sakono et al.
pubs.rsc.org/en/content/a...
October 13, 2025 at 9:14 AM
Reposted by Analytical Methods
In honour of the 2025 #NobelPrize in Chemistry, we’ve curated a collection of impactful articles from across RSC journals on metal–organic frameworks (MOFs) 🏆

Free to read until the end of November 👉 pubs.rsc.org/en/journals/...
October 8, 2025 at 1:12 PM
On the front cover of issue 38 of Analytical Methods:
Comonomer distribution analysis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)s using high-resolution MALDI-TOF mass spectrometry.
Naoki Kanayama et al.
pubs.rsc.org/en/content/a...
October 6, 2025 at 7:46 AM
Reposted by Analytical Methods
(RSC A Meth) Comonomer distribution analysis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)s using high-resolution MALDI-TOF mass spectrometry: Anal. Methods, 2025, 17,7618-7627
DOI: 10.1039/D5AY00910C, PaperNaoki Kanayama, Sayaka Nakamura, Shin Sano, Mami Tanaka, Noriko Takahara,… #MassSpecRSS
Comonomer distribution analysis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)s using high-resolution MALDI-TOF mass spectrometry
Anal. Methods, 2025, 17,7618-7627 DOI: 10.1039/D5AY00910C, PaperNaoki Kanayama, Sayaka Nakamura, Shin Sano, Mami Tanaka, Noriko Takahara, Hiroaki Sato, Hideaki Hagihara The comonomer distribution of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) was depicted as a number distribution plot of 3-hydroxynexanoate via high-resolution mass spectral data analysis. The content of this RSS Feed (c) The Royal Society of Chemistry
dlvr.it
October 3, 2025 at 3:03 AM
Reposted by Analytical Methods
Scientists developed a DNA switch that turns a single viral gene fragment into about 1250 signals, enabling ultra sensitive detection of SARS-CoV-2 down to 0.04 fM and adaptable for other viruses like rabies.

pubs.rsc.org/en/content/a...
An isothermal amplification-bridged ratiometric DNA switch for sensitive detection of viral gene fragments
The detection of viral gene fragments is essential for diagnosing and screening viral infections, managing virus transmission, and controlling epidemics. In this study, we developed an isothermal ampl...
pubs.rsc.org
August 26, 2025 at 6:33 PM
Reposted by Analytical Methods
#NMRchat Optimizing the extraction of ursolic acid from loquat leaf using 1H-qNMR http://pubs.rsc.org/en/Content/ArticleLanding/2025/AY/D5AY01340B
September 30, 2025 at 12:11 PM
In our latest issue:
A pyrolysis gas chromatography high resolution mass spectrometry (Py-GC-MS) method for analysis of phthalic acid esters and its application for screening e-waste materials
Ivan Kourtchev et al
@coventrycawr.bsky.social @deakinuniversity.bsky.social
pubs.rsc.org/en/content/a...
A pyrolysis gas chromatography high resolution mass spectrometry (Py-GC-MS) method for analysis of phthalic acid esters and its application for screening e-waste materials
The increasing volume of electronic waste (e-waste) is a significant global environmental and public health concern. Phthalic acid esters (PAEs) are used as plasticisers in insulation coatings of elec...
pubs.rsc.org
September 30, 2025 at 8:32 AM
Reposted by Analytical Methods
A dual ligand Eu-MOF with high stability and quantum yield for the detection of trace Fe3+, CrO42− and Cr2O72− in aqueous environments http://pubs.rsc.org/en/Content/ArticleLanding/2025/AY/D5AY01329A
September 29, 2025 at 12:15 PM
On the front cover of issue 37 of Analytical Methods:
Sustainable headspace-in-needle microextraction analysis of phthalates using biomass-derived carbon-coated needles.
Sunyoung Bae and Jooyoung Kim.
pubs.rsc.org/en/content/a...
September 29, 2025 at 8:39 AM
Reposted by Analytical Methods
(RSC A Meth) Effects of microscans on the results of orbitrap mass spectrometry analysis of natural organic matter: Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01313E, PaperSophia M. Byvsheva, Mikhail A. Proskurnin, Dmitry S. Volkov
This study experimentally confirms that… #MassSpecRSS
Effects of microscans on the results of orbitrap mass spectrometry analysis of natural organic matter
Anal. Methods, 2025, Advance Article DOI: 10.1039/D5AY01313E, PaperSophia M. Byvsheva, Mikhail A. Proskurnin, Dmitry S. Volkov This study experimentally confirms that averaging individual spectral transients (microscans) is not equivalent to averaging scans. The influence of microscans number is significant and must be considered both during in-laboratory measurements. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
dlvr.it
September 27, 2025 at 4:02 AM
Reposted by Analytical Methods
(RSC A Meth) Rapid characterization of the constituents in Jingfang Granules by ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry: Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01208B, PaperJiaojiao Meng, Yuqi Fu, Lei Liu, Zongyi… #MassSpecRSS
Rapid characterization of the constituents in Jingfang Granules by ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry
Anal. Methods, 2025, Advance Article DOI: 10.1039/D5AY01208B, PaperJiaojiao Meng, Yuqi Fu, Lei Liu, Zongyi Zhou, Le Yang, Ling Kong, Yu Guan, Guimin Zhang, Hui Sun, Chang Liu, Ye Sun, Ying Han, Xijun Wang This study employs UHPLC-QTOF-MS/MS combined with Progenesis QI to systematically identify and profile 132 chemical components in Jingfang Granules (JFG). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
dlvr.it
September 27, 2025 at 5:04 AM
Available to read now via #OpenAccess
pubs.rsc.org/en/content/a...
Fast and sustainable active pharmaceutical ingredient (API) screening in over-the-counter and prescription drug products by surface-assisted plasma-based desorption/ionization high-resolution mass spectrometry
Carsten Engelhard et al
September 25, 2025 at 8:19 AM
Reposted by Analytical Methods
(RSC A Meth) Ambient liquid extraction-mass spectrometry for studying release kinetics of flavor components from tipping papers to oral saliva: Anal. Methods, 2025, Accepted Manuscript
DOI: 10.1039/D5AY00903K, PaperWeiWei Wei, Qinke Li, Ru Ma, Yuqi Cui, S. Ding, Yu Zhao, Qian Wu,… #MassSpecRSS
Ambient liquid extraction-mass spectrometry for studying release kinetics of flavor components from tipping papers to oral saliva
Anal. Methods, 2025, Accepted Manuscript DOI: 10.1039/D5AY00903K, PaperWeiWei Wei, Qinke Li, Ru Ma, Yuqi Cui, S. Ding, Yu Zhao, Qian Wu, Zhiguo Wang A quantitative ambient liquid extraction-mass spectrometry method for flavor components on cigarette tipping paper was developed and utilized to quantify their release kinetics from tipping paper into the oral saliva... The content of this RSS Feed (c) The Royal Society of Chemistry
dlvr.it
September 3, 2025 at 5:04 AM
Reposted by Analytical Methods
(RSC A Meth) A modified QuEChERS method for simultaneous determination of 73 pesticides, 23 PCBs and 16 PAHs in wheat by GC-MS/MS: Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY00950B, PaperMengmeng Yan, Yujie Xie, Mengjie Shi, Xingqiang Wu, Kaixuan Tong, Qiaoying Chang, Hui… #MassSpecRSS
A modified QuEChERS method for simultaneous determination of 73 pesticides, 23 PCBs and 16 PAHs in wheat by GC-MS/MS
Anal. Methods, 2025, Advance Article DOI: 10.1039/D5AY00950B, PaperMengmeng Yan, Yujie Xie, Mengjie Shi, Xingqiang Wu, Kaixuan Tong, Qiaoying Chang, Hui Chen In this study, a modified QuEChERS method for the simultaneous determination of 73 pesticides, 23 PCBs and 16 PAHs in wheat was developed by gas chromatography-triple quadrupole tandem mass spectrometry (GC-MS/MS). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
dlvr.it
September 5, 2025 at 5:04 AM
Reposted by Analytical Methods
A thorough LC-MS/MS strategy to quantify abaloparatide in rat plasma: method development, validation and application #AnalMethods pubs.rsc.org/en/content/a...
A thorough LC-MS/MS strategy to quantify abaloparatide in rat plasma: method development, validation and application
Background: Abaloparatide is a newly approved analog of parathyroid hormone-related peptide. It is used for the treatment of osteoporosis in postmenopausal women who have a high risk of fracture. The ...
pubs.rsc.org
September 5, 2025 at 8:51 AM
Available to read now via #OpenAccess.
Determination of animal species origin of blood in artworks by LC-MS/MS.
Stepanka Kuckova et al
pubs.rsc.org/en/content/a...
September 23, 2025 at 1:25 PM