Amy Thompson
@amyjayyyne.bsky.social
Postdoc crystallographer chilling at synchrotrons and screaming at computers.
Reposted by Amy Thompson
VMXm has postcards! Available from the beamline or a member of the VMXm team if you see us at conferences. Do reach out to us for your microcrystal X-ray diffraction experiments.
September 16, 2025 at 8:16 AM
VMXm has postcards! Available from the beamline or a member of the VMXm team if you see us at conferences. Do reach out to us for your microcrystal X-ray diffraction experiments.
Reposted by Amy Thompson
The first @diamondlightsource.bsky.social MX Newsletter is here! Including the latest news from the MX beamlines, helpful info about shutdowns, runs and training opportunities as well as useful tips and tricks for making the most of the MX beamlines at Diamond. www.diamond.ac.uk/Instruments/...
MX-Newsletter - - Diamond Light Source
This is a periodical newsletter which covers news, updates, and announcements from the MX village. MX-village constitutes of seven macromolecular crystallography beamlines and other associated facilit...
www.diamond.ac.uk
August 27, 2025 at 2:04 PM
The first @diamondlightsource.bsky.social MX Newsletter is here! Including the latest news from the MX beamlines, helpful info about shutdowns, runs and training opportunities as well as useful tips and tricks for making the most of the MX beamlines at Diamond. www.diamond.ac.uk/Instruments/...
Reposted by Amy Thompson
Peter Smyth et al.: Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide ##TimeResolvedXRayCrystallography##SerialCrystallography@Uni_of_Essex...##IUCrhttps://journals.iucr.org/paper?S2052252525006645
Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide
We demonstrate the application of a nitric oxide releasing photocage system for time-resolved serial crystallography studies of two heme containing proteins using a fixed target sample delivery system. Optimal parameters for successful photocage activation and nitric oxide release are explored.
journals.iucr.org
August 23, 2025 at 12:00 AM
Peter Smyth et al.: Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide ##TimeResolvedXRayCrystallography##SerialCrystallography@Uni_of_Essex...##IUCrhttps://journals.iucr.org/paper?S2052252525006645
Reposted by Amy Thompson
New paper describing use of photocaged nitric oxide for time resolved crystallography within fixed targets at XFEL and synchrotron - PhD work of Pete Smyth & Lewis Williams - great collaboration with @jarworrall.bsky.social, beamline I24 and SACLA. Funded by BBSRC
journals.iucr.org/m/issues/202...
journals.iucr.org/m/issues/202...
Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide
We demonstrate the application of a nitric oxide releasing photocage system for time-resolved serial crystallography studies of two heme containing proteins using a fixed target sample delivery system...
journals.iucr.org
August 22, 2025 at 12:52 PM
New paper describing use of photocaged nitric oxide for time resolved crystallography within fixed targets at XFEL and synchrotron - PhD work of Pete Smyth & Lewis Williams - great collaboration with @jarworrall.bsky.social, beamline I24 and SACLA. Funded by BBSRC
journals.iucr.org/m/issues/202...
journals.iucr.org/m/issues/202...
Reposted by Amy Thompson
Registration is open for the September on-site MX user training. If you are an MX user of @diamondlightsource.bsky.social then please to apply to attend - spaces are limited. You'll have the opportunity to visit and learn about all the MX beamlines, data analysis as well as all things logistics.
On-site MX User Training: September - - Diamond Light Source
Training sessions for users of the Macromolecular Crystallography (MX) beamlines
www.diamond.ac.uk
August 7, 2025 at 1:14 PM
Registration is open for the September on-site MX user training. If you are an MX user of @diamondlightsource.bsky.social then please to apply to attend - spaces are limited. You'll have the opportunity to visit and learn about all the MX beamlines, data analysis as well as all things logistics.
Having a great time in York teaching crystallographic data reduction - great to see the students so engaged and asking really good questions! #ccp4
Our @diamondlightsource.bsky.social Amy Thompson teaching scaling, merging and multi crystal data reduction at the #ccp4 #workshop #york #summerschool #crystallography
August 2, 2025 at 1:41 PM
Having a great time in York teaching crystallographic data reduction - great to see the students so engaged and asking really good questions! #ccp4
Wrapped up another conference for the year at the #ACA2025 - thanks to the organisers for putting on a great conference! I greatly enjoyed bringing my work on clustering 🐮🐷🤷♀️ to a new audience - the conference dinner had some pretty neat views too!
July 24, 2025 at 2:38 AM
Wrapped up another conference for the year at the #ACA2025 - thanks to the organisers for putting on a great conference! I greatly enjoyed bringing my work on clustering 🐮🐷🤷♀️ to a new audience - the conference dinner had some pretty neat views too!
Reposted by Amy Thompson
Enhancements of the intensity-clustering algorithms available within DIALS and utilized by xia2.multiplex are described and demonstrated #MultiCrystalDataSets #DataProcessing #Clustering doi.org/10.1107/S205...
June 17, 2025 at 1:28 PM
Enhancements of the intensity-clustering algorithms available within DIALS and utilized by xia2.multiplex are described and demonstrated #MultiCrystalDataSets #DataProcessing #Clustering doi.org/10.1107/S205...
Reposted by Amy Thompson
Paper describing clustering methods to separate subtle structural differences in populations of protein crystals - with application to polymorphs, ligand binding.. - led by Amy Thompson @amyjayyyne.bsky.social with VMXi,I24 and Data Analysis at @ddiamond.bsky.social journals.iucr.org/d/issues/202...
Enhanced intensity-based clustering of isomorphous multi-crystal data sets in the presence of subtle variations
Bovine, porcine and human insulin data sets are isomorphous in terms of unit cell and symmetry. Through enhancements to the multi-crystal clustering methods in DIALS, species-pure data sets are automa...
journals.iucr.org
June 2, 2025 at 7:41 AM
Paper describing clustering methods to separate subtle structural differences in populations of protein crystals - with application to polymorphs, ligand binding.. - led by Amy Thompson @amyjayyyne.bsky.social with VMXi,I24 and Data Analysis at @ddiamond.bsky.social journals.iucr.org/d/issues/202...
Thrilled to have this work published! Thanks to some awesome teamwork, we've demonstrated improvements in multi-crystal data clustering by automatically separating 🐮🐷🧑🔬 #multicrystal #clustering #crystallography doi.org/10.1107/S205...
Enhanced intensity-based clustering of isomorphous multi-crystal data sets in the presence of subtle variations
Bovine, porcine and human insulin data sets are isomorphous in terms of unit cell and symmetry. Through enhancements to the multi-crystal clustering methods in DIALS, species-pure data sets are automa...
doi.org
May 30, 2025 at 10:26 AM
Thrilled to have this work published! Thanks to some awesome teamwork, we've demonstrated improvements in multi-crystal data clustering by automatically separating 🐮🐷🧑🔬 #multicrystal #clustering #crystallography doi.org/10.1107/S205...
This was my first step into the world of XFELs - a great team to collaborate with!
Our new paper exploring the effect of XFEL pulse length and pulse intensity on electron density maps of two radiation sensitive proteins. A great collaboration between Diamond, SwissFEL and University of Essex's Worrall group.
journals.iucr.org/m/issues/202...
journals.iucr.org/m/issues/202...
Damage before destruction? X-ray-induced changes in single-pulse serial femtosecond crystallography
Varied pulse-duration and pulse-intensity serial femtosecond crystallography data do not show significant signs of radiation damage under typical experimental conditions.
journals.iucr.org
April 17, 2025 at 10:35 AM
This was my first step into the world of XFELs - a great team to collaborate with!
Having a great time at the BCA - thanks to the organisers for putting on a great conference and inviting me to present!
Our own @amyjayyyne.bsky.social from @diamondlightsource.bsky.social presenting VMXi at @crystallography.org.uk . Great talk!
April 16, 2025 at 10:46 AM
Having a great time at the BCA - thanks to the organisers for putting on a great conference and inviting me to present!
Reposted by Amy Thompson
Our own @amyjayyyne.bsky.social from @diamondlightsource.bsky.social presenting VMXi at @crystallography.org.uk . Great talk!
April 16, 2025 at 9:23 AM
Our own @amyjayyyne.bsky.social from @diamondlightsource.bsky.social presenting VMXi at @crystallography.org.uk . Great talk!
Reposted by Amy Thompson
Participants in the annual serial crystallography workshop for graduates student some funded by our @wellcometrust.bsky.social PhD program have got homework to do in the evening time …. @diamondlightsource.bsky.social @instruct-eric.bsky.social
April 4, 2025 at 1:20 PM
Participants in the annual serial crystallography workshop for graduates student some funded by our @wellcometrust.bsky.social PhD program have got homework to do in the evening time …. @diamondlightsource.bsky.social @instruct-eric.bsky.social
Super exciting to have this finally out! It was great to have different fields coming together for this collaboration
February 22, 2025 at 2:11 AM
Super exciting to have this finally out! It was great to have different fields coming together for this collaboration