Reposted by Andrew McMullan
Is Cognitive Functional Therapy evidence-based yet? 3 years after the RESTORE trial, a follow-up report says CFT’s back benefits just kept on trucking!
But… 37% of the subjects weren’t included. Classic survivorship bias territory. My notes, 2-min read:
www.painscience.com/blog/cogniti...
But… 37% of the subjects weren’t included. Classic survivorship bias territory. My notes, 2-min read:
www.painscience.com/blog/cogniti...
Cognitive Functional Therapy after 3 years
RESTORE was a clinical trial of Cognitive Functional Therapy, a treatment for back pain that targets maladaptive…
www.painscience.com
August 15, 2025 at 6:25 PM
Is Cognitive Functional Therapy evidence-based yet? 3 years after the RESTORE trial, a follow-up report says CFT’s back benefits just kept on trucking!
But… 37% of the subjects weren’t included. Classic survivorship bias territory. My notes, 2-min read:
www.painscience.com/blog/cogniti...
But… 37% of the subjects weren’t included. Classic survivorship bias territory. My notes, 2-min read:
www.painscience.com/blog/cogniti...
Reposted by Andrew McMullan
Perceptions and beliefs of physical therapists regarding the mechanisms of manual therapy www.sciencedirect.com/science/arti...
Mechanisms such as endogenous pain modulation (73 %), placebo effects (72 %), muscle activity (68 %), and neuromuscular responses (62 %) were commonly endorsed
Mechanisms such as endogenous pain modulation (73 %), placebo effects (72 %), muscle activity (68 %), and neuromuscular responses (62 %) were commonly endorsed
August 13, 2025 at 12:42 PM
Perceptions and beliefs of physical therapists regarding the mechanisms of manual therapy www.sciencedirect.com/science/arti...
Mechanisms such as endogenous pain modulation (73 %), placebo effects (72 %), muscle activity (68 %), and neuromuscular responses (62 %) were commonly endorsed
Mechanisms such as endogenous pain modulation (73 %), placebo effects (72 %), muscle activity (68 %), and neuromuscular responses (62 %) were commonly endorsed
Reposted by Andrew McMullan
Reposted by Andrew McMullan
Check out this thread on the excellent work @jdwilko.bsky.social is doing to develop tools to assess trustworthiness of clinical trials
We applied a long list of trustworthiness checks to RCTs in 50 Cochrane Reviews with the goal of learning a bit more about the checks. A few take-aways.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Assessing the feasibility and impact of clinical trial trustworthiness checks via an application to Cochrane Reviews: Stage 2 of the INSPECT-SR project
The aim of the INveStigating ProblEmatic Clinical Trials in Systematic Reviews (INSPECT-SR) project is to develop a tool to identify problematic RCTs …
www.sciencedirect.com
June 26, 2025 at 12:11 PM
Check out this thread on the excellent work @jdwilko.bsky.social is doing to develop tools to assess trustworthiness of clinical trials
Reposted by Andrew McMullan
Pounding the pavement is not a major driver of arthritis, as shown in 2024 study. (This one via @running-physio.bsky.social, thanks Tom.)
So what DOES drive arthritis? Age. Poor fitness. Old injuries/surgeries. And much of that is mediated by GENES, of course. 🧬 Let me spell that out a bit…
So what DOES drive arthritis? Age. Poor fitness. Old injuries/surgeries. And much of that is mediated by GENES, of course. 🧬 Let me spell that out a bit…
June 5, 2025 at 5:09 PM
Pounding the pavement is not a major driver of arthritis, as shown in 2024 study. (This one via @running-physio.bsky.social, thanks Tom.)
So what DOES drive arthritis? Age. Poor fitness. Old injuries/surgeries. And much of that is mediated by GENES, of course. 🧬 Let me spell that out a bit…
So what DOES drive arthritis? Age. Poor fitness. Old injuries/surgeries. And much of that is mediated by GENES, of course. 🧬 Let me spell that out a bit…
Reposted by Andrew McMullan
🔥 Most important paper I've read all year🔥
👉 Injury/disease doesn't reliably predict pain
👉 Biomarkers alone can't explain pain
👉 PSYCHOSOCIAL factors reliably determine chronic pain
👉 Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors
www.nature.com/articles/s41...
👉 Injury/disease doesn't reliably predict pain
👉 Biomarkers alone can't explain pain
👉 PSYCHOSOCIAL factors reliably determine chronic pain
👉 Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors
www.nature.com/articles/s41...
Biological markers and psychosocial factors predict chronic pain conditions - Nature Human Behaviour
Fillingim et al. show that biological and psychosocial factors jointly predict conditions associated with chronic pain.
www.nature.com
May 14, 2025 at 3:18 AM
🔥 Most important paper I've read all year🔥
👉 Injury/disease doesn't reliably predict pain
👉 Biomarkers alone can't explain pain
👉 PSYCHOSOCIAL factors reliably determine chronic pain
👉 Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors
www.nature.com/articles/s41...
👉 Injury/disease doesn't reliably predict pain
👉 Biomarkers alone can't explain pain
👉 PSYCHOSOCIAL factors reliably determine chronic pain
👉 Painful conditions can be predicted from the SYNERGY btwn bio + psychosocial factors
www.nature.com/articles/s41...
Reposted by Andrew McMullan
More #shockwave doubts, this time from salamander-friend Scott Gavura (@pharmacistscott.sciencebasedmedicine.org), resident skeptical pharmacist at @sciencebasedmedicine.org.web.brid.gy.
1-min read, 5 if you go on to Scott's post:
www.painscience.com/blog/more-sh...
1-min read, 5 if you go on to Scott's post:
www.painscience.com/blog/more-sh...
More shockwave doubts
Scott Gavura, a long-time runner and the resident skeptical pharmacist at ScienceBasedMedicine.org: “Given I’m…
www.PainScience.com
May 14, 2025 at 12:01 AM
More #shockwave doubts, this time from salamander-friend Scott Gavura (@pharmacistscott.sciencebasedmedicine.org), resident skeptical pharmacist at @sciencebasedmedicine.org.web.brid.gy.
1-min read, 5 if you go on to Scott's post:
www.painscience.com/blog/more-sh...
1-min read, 5 if you go on to Scott's post:
www.painscience.com/blog/more-sh...
Reposted by Andrew McMullan
F&A Structures - Tendons, Blood Vessels & Nerves 🦶🏼
Image adapted from Dr John Kenneth Dickson and ‘Picturing Medicine’… ✏️🎨😍
Image adapted from Dr John Kenneth Dickson and ‘Picturing Medicine’… ✏️🎨😍
December 30, 2024 at 6:10 PM
F&A Structures - Tendons, Blood Vessels & Nerves 🦶🏼
Image adapted from Dr John Kenneth Dickson and ‘Picturing Medicine’… ✏️🎨😍
Image adapted from Dr John Kenneth Dickson and ‘Picturing Medicine’… ✏️🎨😍
Reposted by Andrew McMullan
Not even got time for a journal paper? This short explainer video will give you a good flavour lnkd.in/ePAPJWeD
December 21, 2024 at 10:09 PM
Not even got time for a journal paper? This short explainer video will give you a good flavour lnkd.in/ePAPJWeD
Reposted by Andrew McMullan
Obesity, Osteoarthritis, and Myokines: Balancing Weight Management Strategies, Myokine Regulation, and Muscle Health
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
December 18, 2024 at 11:55 AM
Obesity, Osteoarthritis, and Myokines: Balancing Weight Management Strategies, Myokine Regulation, and Muscle Health
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Reposted by Andrew McMullan
BLUESKY MEGA-THREAD
Altmetric is thrilled and also LITERALLY RELIEVED to officially announce:
We are now tracking research attention as it happens on Bluesky!
We have been picking up posts on the site since late Oct.
Our team is on Bluesky all day answering questions.
Let's get into it!
Altmetric is thrilled and also LITERALLY RELIEVED to officially announce:
We are now tracking research attention as it happens on Bluesky!
We have been picking up posts on the site since late Oct.
Our team is on Bluesky all day answering questions.
Let's get into it!
December 3, 2024 at 2:00 PM
BLUESKY MEGA-THREAD
Altmetric is thrilled and also LITERALLY RELIEVED to officially announce:
We are now tracking research attention as it happens on Bluesky!
We have been picking up posts on the site since late Oct.
Our team is on Bluesky all day answering questions.
Let's get into it!
Altmetric is thrilled and also LITERALLY RELIEVED to officially announce:
We are now tracking research attention as it happens on Bluesky!
We have been picking up posts on the site since late Oct.
Our team is on Bluesky all day answering questions.
Let's get into it!
Reposted by Andrew McMullan
New study of pelvic floor muscle strength (PFM) in women is at odds with a theory I floated recently—ack!—but it's kind of a good/bad news thing …
The good: Heavy weighlifting is nevertheless "well-tolerated" by women, which is another blow to the myth of feminine fragility. Noice. 👍🏻
The good: Heavy weighlifting is nevertheless "well-tolerated" by women, which is another blow to the myth of feminine fragility. Noice. 👍🏻
November 26, 2024 at 7:26 PM
New study of pelvic floor muscle strength (PFM) in women is at odds with a theory I floated recently—ack!—but it's kind of a good/bad news thing …
The good: Heavy weighlifting is nevertheless "well-tolerated" by women, which is another blow to the myth of feminine fragility. Noice. 👍🏻
The good: Heavy weighlifting is nevertheless "well-tolerated" by women, which is another blow to the myth of feminine fragility. Noice. 👍🏻