Alexandra Whiteley
@alexwhiteley.bsky.social
Assistant professor of Biochemistry @CU Boulder. We study Ubiquilins and how dysregulation of the virus-like protein PEG10 contributes to neurodegenerative disease upon UBQLN2 mutation. I'm lucky to lead a great group of scientists in a beautiful place!
I'm so excited to see this Perspective with @jasonsynaptic.bsky.social out in Neuron! About 8% of our genome is made up of the remnants of LTR-containing retroelements - here, Jason and I explore the activities of retroTEs in neurological health and disease!
authors.elsevier.com/c/1lzTx3BtfH...
authors.elsevier.com/c/1lzTx3BtfH...
authors.elsevier.com
October 23, 2025 at 3:15 PM
I'm so excited to see this Perspective with @jasonsynaptic.bsky.social out in Neuron! About 8% of our genome is made up of the remnants of LTR-containing retroelements - here, Jason and I explore the activities of retroTEs in neurological health and disease!
authors.elsevier.com/c/1lzTx3BtfH...
authors.elsevier.com/c/1lzTx3BtfH...
Reposted by Alexandra Whiteley
The GRFP announcement from NSF cuts out an entire cohort of 2nd year students from consideration, without warning. This is so deeply unfair that it warrants a formal protest from the scientific community. If someone wants to work with me to craft an open letter and solicit signatures, LMK.
New: After a long wait, the GRFP solicitation is live! Deadlines have been extended to early November, so applicants have a bit over a month to submit. www.nsf.gov/funding/oppo...
NSF Graduate Research Fellowship Program (GRFP)
www.nsf.gov
September 26, 2025 at 5:10 PM
The GRFP announcement from NSF cuts out an entire cohort of 2nd year students from consideration, without warning. This is so deeply unfair that it warrants a formal protest from the scientific community. If someone wants to work with me to craft an open letter and solicit signatures, LMK.
"I refused to write you a promotion letter because we did our undergrad studies together and I thought that might be a conflict of interest"
July 29, 2025 at 5:35 PM
The Summer Is Magic - Radio Mix
Playahitty · The Summer Is Magic - Ep · Song · 1994
open.spotify.com
July 23, 2025 at 10:24 PM
This may or may not be me rn
#alsgrc
#alsgrc
PI 🧪 meeting poster prep:
1. Submit an abstract while registering.
2. Realize a week before the meeting that you must make a poster.
3. Realize you do not know how to do this.
4. Ask a lab member for a poster template.
5. Try to edit the template. Fail.
6. Ask a lab member to make your poster 🤓
1. Submit an abstract while registering.
2. Realize a week before the meeting that you must make a poster.
3. Realize you do not know how to do this.
4. Ask a lab member for a poster template.
5. Try to edit the template. Fail.
6. Ask a lab member to make your poster 🤓
July 21, 2025 at 7:58 PM
This may or may not be me rn
#alsgrc
#alsgrc
So excited to head to Mexico in a few months for #erehd25, it’s going to be a blast! Join us!
Are you currently in the ERE related field & want to find new collaborative opportunities? Join our Chairs @chiappinellilab.bsky.social, @shenhui1986.bsky.social, Ting & Tao at #EREHD25 this Nov!
🎙️Talk Submission extended to 03 Sept
💰Final few $500 grants remaining
Don't Miss out! bit.ly/4eRq9Mp
🎙️Talk Submission extended to 03 Sept
💰Final few $500 grants remaining
Don't Miss out! bit.ly/4eRq9Mp
July 17, 2025 at 5:56 PM
So excited to head to Mexico in a few months for #erehd25, it’s going to be a blast! Join us!
Wow, wow, wow! Can’t wait to dive in to this more - amazing work @mollygale.bsky.social and @nygenome.org !! So much to learn from this great work!
Super happy to announce the latest work from my lab together with Hemali Phatnani @nygenome.org & NYGC ALS Consortium!
We've combined ALS patient profiling (100s!), ML classifiers and matched bulk/single-cell data to dive into ALS Molecular Subtypes
#NIHfundedResearch
www.cell.com/cell-reports...
We've combined ALS patient profiling (100s!), ML classifiers and matched bulk/single-cell data to dive into ALS Molecular Subtypes
#NIHfundedResearch
www.cell.com/cell-reports...
ALS molecular subtypes are a combination of cellular and pathological features learned by deep multiomics classifiers
O’Neill et al. present a deep exploration of molecular subtypes in ALS postmortem
tissues from the NYGC ALS Consortium. Matched bulk and single-cell profiles demonstrate
that ALS subtypes are a combin...
www.cell.com
March 10, 2025 at 10:22 PM
Wow, wow, wow! Can’t wait to dive in to this more - amazing work @mollygale.bsky.social and @nygenome.org !! So much to learn from this great work!
Reposted by Alexandra Whiteley
Interrupting your doom scrolling for some light hearted fun. Vote for us in the @statnews.com madness competition! Based on our work @cellpress.bsky.social on Paraneoplastic disorders..we are on the RH side of the bracket. www.statnews.com/feature/stat...
2025 STAT Madness
2025 bracket Welcome to STAT Madness, a bracket-style contest to find the best innovation in science and medicine. Explore groundbreaking innovations from
www.statnews.com
March 3, 2025 at 3:47 PM
Interrupting your doom scrolling for some light hearted fun. Vote for us in the @statnews.com madness competition! Based on our work @cellpress.bsky.social on Paraneoplastic disorders..we are on the RH side of the bracket. www.statnews.com/feature/stat...
Oh no Mike! I loved Open Mike 😢
Mike Lauer follows Lawrence Tabak out the door at NIH www.statnews.com/2025/02/13/n...
Second top NIH official, who oversaw awarding of research grants, departs abruptly
Michael Lauer, deputy director of the National Institutes of Health’s extramural research, will leave the agency at the end of the week.
www.statnews.com
February 14, 2025 at 6:16 PM
Oh no Mike! I loved Open Mike 😢
I'm an American academic who started my lab in 2020, currently with two kids under 6, and I have to say... I love the Lego Movie 2 open.spotify.com/track/2T909y...
Everything's Not Awesome
open.spotify.com
February 4, 2025 at 8:28 PM
I'm an American academic who started my lab in 2020, currently with two kids under 6, and I have to say... I love the Lego Movie 2 open.spotify.com/track/2T909y...
@adelitadmendoza.bsky.social new lab decor perhaps? I think the fourth floor could use some neon!
December 31, 2024 at 5:53 PM
@adelitadmendoza.bsky.social new lab decor perhaps? I think the fourth floor could use some neon!
I'm thrilled to have received a CDMRP Therapeutic Idea Award for the development of experimental ALS therapeutics! This will fund two years of work on novel ASOs and small molecule inhibitors of the virus-like protein PEG10. We're excited to get started!
cdmrp.health.mil/alsrp/awards...
cdmrp.health.mil/alsrp/awards...
cdmrp.health.mil
December 27, 2024 at 4:50 PM
I'm thrilled to have received a CDMRP Therapeutic Idea Award for the development of experimental ALS therapeutics! This will fund two years of work on novel ASOs and small molecule inhibitors of the virus-like protein PEG10. We're excited to get started!
cdmrp.health.mil/alsrp/awards...
cdmrp.health.mil/alsrp/awards...
A very interesting article - the Spring semester begins in a few weeks and I'm looking forward to getting started with a new batch of students. Maybe a brief comment is in order.
www.nytimes.com/2024/12/26/o...
www.nytimes.com/2024/12/26/o...
Opinion | No, You Don’t Get an A for Effort
High marks reward excellence, not grit.
www.nytimes.com
December 26, 2024 at 5:44 PM
A very interesting article - the Spring semester begins in a few weeks and I'm looking forward to getting started with a new batch of students. Maybe a brief comment is in order.
www.nytimes.com/2024/12/26/o...
www.nytimes.com/2024/12/26/o...
Join my new colleague in Boulder! I can attest to the view and Adelita is a rising star! 💫🏔️🔬
The Mendoza lab is hiring a Research Assistant at the University of Colorado Boulder!! Come join our brand new lab as we launch our group! We study zinc homeostasis using a variety of techniques in C. elegans and human models. The view in Boulder ain't bad either! Reach out with questions!
December 7, 2024 at 4:31 AM
Join my new colleague in Boulder! I can attest to the view and Adelita is a rising star! 💫🏔️🔬
Feeling great as we get into this holiday season… no Thanksgiving disasters and some great news about a grant! #rested #notreally #bringiton
December 3, 2024 at 3:17 PM
Feeling great as we get into this holiday season… no Thanksgiving disasters and some great news about a grant! #rested #notreally #bringiton
Reposted by Alexandra Whiteley
PIONEERS
When I assumed the position as Director of NIGMS in 2003, Dr. Zerhouni's project for stimulating activities across NIH, The NIH Roadmap for Medical Research, was under active development. The Roadmap included a range of different funding opportunities.
1/n
www.science.org/content/arti...
When I assumed the position as Director of NIGMS in 2003, Dr. Zerhouni's project for stimulating activities across NIH, The NIH Roadmap for Medical Research, was under active development. The Roadmap included a range of different funding opportunities.
1/n
www.science.org/content/arti...
NIH's Roadmap to the Future
www.science.org
November 22, 2024 at 12:12 PM
PIONEERS
When I assumed the position as Director of NIGMS in 2003, Dr. Zerhouni's project for stimulating activities across NIH, The NIH Roadmap for Medical Research, was under active development. The Roadmap included a range of different funding opportunities.
1/n
www.science.org/content/arti...
When I assumed the position as Director of NIGMS in 2003, Dr. Zerhouni's project for stimulating activities across NIH, The NIH Roadmap for Medical Research, was under active development. The Roadmap included a range of different funding opportunities.
1/n
www.science.org/content/arti...
Publication timelines are such a killer. My lab had our second research paper accepted in September, but are still awaiting final publication. Will it be published in 2024? Only time will tell... #waiting #emailing #waitingmore
November 18, 2024 at 10:43 PM
Publication timelines are such a killer. My lab had our second research paper accepted in September, but are still awaiting final publication. Will it be published in 2024? Only time will tell... #waiting #emailing #waitingmore
Hi Bluesky! Know anyone interested in a Biochemistry PhD program? The CU Boulder Biochemistry program is a wonderful vibrant training environment in beautiful Boulder Colorado! Our deadline for applications is November 15th, so apply soon! www.colorado.edu/biochemistry...
Prospective Graduate Students
www.colorado.edu
November 11, 2024 at 8:47 PM
Hi Bluesky! Know anyone interested in a Biochemistry PhD program? The CU Boulder Biochemistry program is a wonderful vibrant training environment in beautiful Boulder Colorado! Our deadline for applications is November 15th, so apply soon! www.colorado.edu/biochemistry...
It’s so nice to see so much science in my Bluesky feed! So many new papers to look at! 😊
October 30, 2024 at 12:37 PM
It’s so nice to see so much science in my Bluesky feed! So many new papers to look at! 😊
Please consider donating to this GoFundMe that supports the young family of my late colleague Dr. Jeff Cameron. He unexpectedly passed away in late September and we are all heartbroken.
gofund.me/fc744581
gofund.me/fc744581
Donate to Help Support a More Stable Future for Jeff Cameron's Family, organized by Merritt Turetsky
On September 25, 2024, Jeff Cameron passed away suddenly and … Merritt Turetsky needs your support for Help Support a More Stable Future for Jeff Cameron's Family
gofund.me
October 8, 2024 at 11:12 PM
Please consider donating to this GoFundMe that supports the young family of my late colleague Dr. Jeff Cameron. He unexpectedly passed away in late September and we are all heartbroken.
gofund.me/fc744581
gofund.me/fc744581
Anyone else from bsky here @ #EMBOubiquitin2024 ?
September 28, 2024 at 9:02 AM
Anyone else from bsky here @ #EMBOubiquitin2024 ?
Finally getting a chance to breathe and debrief from an awesome few weeks. Last week I got back from the #LiveLikeLou Symposium where I got to share my lab's research on UBQLN2 and PEG10. It was an incredible experience and I hope to go again in 2026!
August 6, 2024 at 10:01 PM
Finally getting a chance to breathe and debrief from an awesome few weeks. Last week I got back from the #LiveLikeLou Symposium where I got to share my lab's research on UBQLN2 and PEG10. It was an incredible experience and I hope to go again in 2026!
Reposted by Alexandra Whiteley
Characterization of Medusavirus encoded histones reveals nucleosome-like structures and a unique linker histone https://www.biorxiv.org/content/10.1101/2024.04.13.589364v1
Characterization of Medusavirus encoded histones reveals nucleosome-like structures and a unique linker histone https://www.biorxiv.org/content/10.1101/2024.04.13.589364v1
The organization of DNA into nucleosomes is a ubiquitous and ancestral feature that was once thought
www.biorxiv.org
April 15, 2024 at 3:18 AM
Characterization of Medusavirus encoded histones reveals nucleosome-like structures and a unique linker histone https://www.biorxiv.org/content/10.1101/2024.04.13.589364v1
March 6, 2024 at 5:55 PM