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acasadevall1.bsky.social
@acasadevall1.bsky.social
810 followers 36 following 13 posts
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acasadevall1.bsky.social
Research inspired by melanin studies with C. neoformans suggests new approach to mosquito control for malaria.

publichealth.jhu.edu/malaria-rese...
The Goldilocks Dose: Modulating Mosquito Diet to Control Malaria | Johns Hopkins Malaria Research Institute
Feeding mosquitoes L-DOPA can either strengthen their defences against malaria or shorten their lifespan — showing that in vector control, the dose makes the difference
publichealth.jhu.edu
September 11, 2025 at 11:20 PM
Reposted
cmicomms.bsky.social
🎙️ Just published a new #Communicable episode: Communicab...

Hosted by Angela Huttner @angelahuttner.bsky.social
Josh Nosanchuk @josh-nosanchuk.bsky.social

with invited guest:
Arturo Casadevall @acasadevall1.bsky.social (Johns Hopkins University)

Listen here:

#IDSky #Clinmicro #MedSky
Communicable E31: Climate change and fungal spread
The adaptability of fungi to warmer temperatures is an obvious...
share.transistor.fm
July 13, 2025 at 10:01 PM
Reposted
cmicomms.bsky.social
📣 Next #Communicable drops Mon 14 July!
@angelahuttner.bsky.social & @josh-nosanchuk.bsky.social invite Arturo Casadevall @acasadevall1.bsky.social (Johns Hopkins) to discuss the spread of #fungi due to climate change, and what that means for fungal pathogenesis & infection
#IDSky #clinmicro #MedSky
July 10, 2025 at 10:03 AM
acasadevall1.bsky.social
Quoted here about the increasing problem of drug resistance in Aspergillus isolates.
www.nbcnews.com/health/healt...
Fungal infections are getting harder to treat
The fungus Aspergillus fumigatus tops the World Health Organization's list of worrying fungal diseases. It's growing increasingly resistant to the first-line drug used to treat it.
www.nbcnews.com
July 9, 2025 at 11:13 PM
Reposted
plosbiology.org
To what extent can we predict future pathogenic #microbes? @acasadevall1.bsky.social discusses why probabilistic predictions are difficult, but not impossible. 🧪
plos.io/3EXieQp
Is pathogen prediction possible?
To what extent can we predict future pathogenic microbes? This Perspective discusses why complex requirements for virulence and dynamic host-microbe interactions make probabilistic predictions difficu...
plos.io
May 16, 2025 at 4:38 PM
Reposted
johnshopkinsmmi.bsky.social
CAN WE STOP KILLER FUNGI?
Fungal diseases are more common, more dangerous & more difficult to treat. This fascinating BBC podcast features 4 global #fungi experts including @johnshopkinssph.bsky.social @jhu.edu @acasadevall1.bsky.social - interview at 10:55 time marker
www.bbc.co.uk/sounds/play/...
The Inquiry - Can we stop killer fungi? - BBC Sounds
Why fungal diseases are becoming more dangerous to human health
www.bbc.co.uk
May 28, 2025 at 9:52 PM
Reposted
carlzimmer.com
The Last of Us may be over for now, but fungus pandemic news endures. Here's my story on how white-nose disease, which has battered North American bats, may have more devastation in store. 🧪 Gift link: nyti.ms/4mGRyV8
A Fungus Devastated North American Bats. A New Species Could Deliver a Killer Blow. (Gift Article)
Scientists have learned that another species of fungus found in Europe and Asia causes white-nose disease, which has ravaged bat populations in the United States and Canada.
nyti.ms
May 28, 2025 at 3:16 PM
Reposted
labwaggoner.bsky.social
Review @natrevimmunol.bsky.social @acasadevall1.bsky.social
New insights into antibody structure with implications for specificity, variable region restriction and isotype choice
www.nature.com/articles/s41...
New insights into antibody structure with implications for specificity, variable region restriction and isotype choice - Nature Reviews Immunology
Immunoglobulins sample vast swathes of primary sequence and conformational space to generate and select B cell clones with exquisite selectivity and affinity for specific antigens. This Perspective ar...
www.nature.com
March 21, 2025 at 6:53 PM
Reposted
hyphaltip.bsky.social
share.transistor.fm/s/ee922716 - nice interview with Joe Heitman on Fungi
Cosmic Radio Interview with Dr. Joseph Heitman: Professor and Chair of Molecular Genetics and Professor in Medicine at Duke University and CIFAR's Co-Director for the Fungal Kingdom: Threats & Opportu...
Join me on Cosmic Radio as we speak with Dr. Joseph Heitman. Dr. Heitman is a professor and Chair of Molecular Biology and Professor in Medicine at Duke University and CIFAR's Co-Director for the "Fun...
share.transistor.fm
May 10, 2025 at 7:30 PM
Reposted
johnshopkinsmmi.bsky.social
A tribute to @johnshopkinssph.bsky.social Professor Diane Griffin, MD, PhD, noted virologist, former @johnshopkinsmmi.bsky.social dept chair, written by @acasadevall1.bsky.social & J. Marie Hardwick, published in @pnas.org

@jhu.edu @hopkinsmedicine.bsky.social

www.pnas.org/doi/10.1073/...
Diane E. Griffin, physician–scientist extraordinaire | PNAS
In October 2024, the scientific world lost Diane E. Griffin, a highly accomplished physician–scientist who greatly heightened our understanding of ...
www.pnas.org
May 1, 2025 at 10:59 PM
Reposted
netec.org
🧟‍♂️ #TheLastOfUs S2 drops April 13—brush up on the science behind the spores with this throwback.

🎧 In #NETEC’s #FungalPathogens podcast episode, Dr. Arturo Casadevall (@acasadevall1.bsky.social) breaks down the fungal fact vs. fiction behind the show.

Listen now:
Pathogens in Pop Culture: Fungal Pathogens and The Last of Us
Could a fungus cause the next pandemic? Separating myth from reality; examining the science behind fungal pathogens.
netec.org
April 11, 2025 at 4:05 PM
Reposted
natrevimmunol.nature.com
New Perspective article from Scott McConnell & @acasadevall1.bsky.social @johnshopkinssph.bsky.social highlights the importance of constant regions in influencing the specificity and functionality of #antibodies
#immunology #immunosky
New insights into antibody structure with implications for specificity, variable region restriction and isotype choice - Nature Reviews Immunology
Immunoglobulins sample vast swathes of primary sequence and conformational space to generate and select B cell clones with exquisite selectivity and affinity for specific antigens. This Perspective article examines the interplay between antibody diversification mechanisms and highlights the importance of constant regions in influencing the specificity and functionality of individual antibodies.
www.nature.com
March 20, 2025 at 3:47 PM
acasadevall1.bsky.social
I don't understand why articles like this one never mention that we have an option for preventing disease: measles gamma globulin has a 100% efficacy in preventing disease in exposed vulnerable children. See this reference:
pubmed.ncbi.nlm.nih.gov/29028959/.
www.nytimes.com/2025/03/14/w...
Parents of Babies Who Are Too Young for Measles Vaccine Worry About Outbreaks
Infants are at higher risk of complications from the measles but can’t be vaccinated right away.
www.nytimes.com
March 14, 2025 at 3:31 PM
Reposted
markowenmartin.bsky.social
It's Thursday: time for #MattersMicrobial Episode #82! Dr. Arturo Casadevall talks with the #QualityQuorum about how fungi can use melanin to collect energy from light (and radiation), and adaptation to high temperatures. Please spread the #GoodMicrobialWord!

youtu.be/D7uzJzglC40?...
March 13, 2025 at 8:56 PM
Reposted
stcmicrobeblog.bsky.social
check #MattersMicrobial #82 👇

...and as "supplementary material" >
schaechter.asmblog.org/schaechter/2...
#FungiFriends
March 13, 2025 at 9:40 PM
Reposted
markowenmartin.bsky.social
Today's podcast recording session for #MattersMicrobial was with the amazing Dr. Arturo Casadevall. He has such interesting ideas, and I cannot wait to share them with you.
March 6, 2025 at 8:43 PM
acasadevall1.bsky.social
The pandemic crisis may be over, but SARS-CoV-2 remains a major problem for the immunocompromised that do not make good antibody responses. European RCT confirms efficacy of COVID-19 convalescent plasma (CCP) in this population. CCP is FDA licensed in US
March 1, 2025 at 3:11 PM
acasadevall1.bsky.social
As physicians confront the widening measles outbreak it is important to keep in mind that we have a highly effective means of protecting those exposed - hyperimmune IgG. It showed 100% efficacy in the 2013 NYC outbreak.
March 1, 2025 at 11:26 AM
Reposted
labwaggoner.bsky.social
A call for the United States to continue investing in science
journals.asm.org/doi/10.1128/...
@acasadevall1.bsky.social @bladerlab.bsky.social @goodrumviruslab.bsky.social
Highlights of U.S. government-funded advances in biomedical sciences/healthcare:
February 27, 2025 at 5:10 PM
acasadevall1.bsky.social
As we enter another week of crisis in the biomedical sciences, I thought I would make a list of the advances in field of infectious diseases THAT I HAVE WITNESSED since I became board certified in 1990. I am sure I missed a few advances, and this is only in the field of ID.
February 22, 2025 at 4:13 PM
acasadevall1.bsky.social
Five years after it became the first emergency therapy for COVID-19 convalescent plasma is FDA licensed, effective, safe and relatively inexpensive since it is a donated product and keeps up with the variants.
hub.jhu.edu/2025/02/03/i...
Convalescent plasma offers a 'blueprint' for future pandemics
Hopkins researchers help secure full FDA approval to treat immunocompromised COVID-19 patients—paving the way to explore using convalescent plasma during future infectious disease outbreaks
hub.jhu.edu
February 22, 2025 at 1:51 AM
Reposted
jhu-bdps.bsky.social
JHU has established a planning committee for immunology. The committee will be co-chaired by two Bloomberg Distinguished Professors, @acasadevall1.bsky.social and Erika Pearce, and BDP Nicole Baumgarth will be a member of the committee.

hub.jhu.edu/2025/02/11/n...
Committee imagines a new future for immunology research at Johns Hopkins
10-member committee aims to create a groundbreaking, interdivisional organizing structure for immunology at Hopkins
hub.jhu.edu
February 19, 2025 at 2:23 PM
Reposted
felipehst.bsky.social
Hey #fungal people - the applications for this years MOMY course are open! Wonderful course in a wonderful place with wonderful people. Check it out here: www.mbl.edu/education/ad...
February 10, 2025 at 7:13 PM
acasadevall1.bsky.social
Warmer climates could supercharge fungal diseases transmitted by insects. pubmed.ncbi.nlm.nih.gov/39907444/
February 6, 2025 at 12:17 AM
Reposted
rolandoug.bsky.social
If you're a pediatrician you should read this nice recent paper by @acasadevall1.bsky.social et al about the discovery of #RSV, the history and scientists behind it, and go back to those years. We've reached recently amazing advances in prevention. #medsky #idsky #pedssky
doi.org/10.1128/mbio...
The Story behind the Science: On the discovery of respiratory syncytial virus | mBio
Today, respiratory syncytial virus (RSV) is the leading cause of infant hospitalizations (1) and a significant cause of morbidity and mortality among older individuals (2). On 3 May 2024, the Johns Ho...
doi.org
February 1, 2025 at 12:03 AM