Ahmed Balboula
@abalboula.bsky.social
Reproductive and Cell Biologist, Associate Professor, University of Missouri
Thanks for the highlight, Gabrielle!
Happy Sunday! Ready for the latest papers on #oocyte cell biology?
Here they come! biomed.news/bims-cebooc/...
Highlight: pubmed.ncbi.nlm.nih.gov/40973727/ by @abalboula.bsky.social and @ejsm9.bsky.social
Thanks @biomednews.bsky.social for preselecting!
Here they come! biomed.news/bims-cebooc/...
Highlight: pubmed.ncbi.nlm.nih.gov/40973727/ by @abalboula.bsky.social and @ejsm9.bsky.social
Thanks @biomednews.bsky.social for preselecting!
September 21, 2025 at 2:54 PM
Thanks for the highlight, Gabrielle!
Excited to share our latest work led by our talented PhD student @ejsm9.bsky.social We show that Myosins X/VIIb localize F-actin to the spindle&MTOCs in oocytes. With photoswitchable Optojasp, we reveal that spindle/MTOC-localized F-actin drives spindle pole focusing &accurate chromosome segregation
Spindle-localized F-actin regulates polar MTOC organization and the fidelity of meiotic spindle formation - Nature Communications
Errors in oocyte division can cause infertility and birth defects. Here, authors combine a genetic strategy with a novel optochemical tool to show that spindle pole-localized F-actin is essential for ...
www.nature.com
September 19, 2025 at 2:08 PM
Excited to share our latest work led by our talented PhD student @ejsm9.bsky.social We show that Myosins X/VIIb localize F-actin to the spindle&MTOCs in oocytes. With photoswitchable Optojasp, we reveal that spindle/MTOC-localized F-actin drives spindle pole focusing &accurate chromosome segregation
Reposted by Ahmed Balboula
I'm thrilled to share that our story is now out in Science Advances! 🎉 We use quantitative imaging to map the mito central dogma, define translation hubs in the mitochondrial matrix, and show that they're replaced by Mitochondrial Stress Bodies (MSB) when mtRNA processing is perturbed 1/4
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress | Science Advances www.science.org/doi/10.1126/...
Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress
Quantitative imaging of the mitochondrial central dogma identifies translation hubs that are suppressed during stress.
www.science.org
April 18, 2025 at 10:56 PM
I'm thrilled to share that our story is now out in Science Advances! 🎉 We use quantitative imaging to map the mito central dogma, define translation hubs in the mitochondrial matrix, and show that they're replaced by Mitochondrial Stress Bodies (MSB) when mtRNA processing is perturbed 1/4
Reposted by Ahmed Balboula
I have exhorted others to share positive news even in these uncertain times for US science.
I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online.
Follow along here 🧪🧵
I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online.
Follow along here 🧪🧵
Our study exploring the evolutionary mechanism of alphavirus opal codon retention is now online! www.science.org/doi/10.1126/...
A conserved opal termination codon optimizes a temperature-dependent trade-off between protein production and processing in alphaviruses
Alphaviruses optimize viral polymerase production and polyprotein processing at distinct temperatures via a premature stop codon.
www.science.org
April 18, 2025 at 11:11 PM
I have exhorted others to share positive news even in these uncertain times for US science.
I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online.
Follow along here 🧪🧵
I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online.
Follow along here 🧪🧵
Reposted by Ahmed Balboula
New Akera's lab paper! Congrats @takashiakeralab.bsky.social and Eddie!
Meiosis-specific distal cohesion site decoupled from the kinetochore - Nature Communications
In general, the kinetochore position and the sister-chromatid cohesion site are spatially linked. Here, the authors find a meiosis-specific distal cohesion site decoupled from the kinetochore in Perom...
www.nature.com
March 3, 2025 at 2:33 PM
New Akera's lab paper! Congrats @takashiakeralab.bsky.social and Eddie!
Reposted by Ahmed Balboula
the version of record (VoR) of our most recent paper has been published @elife.bsky.social! 🎉🥳 🧪
elifesciences.org/articles/102...
elifesciences.org/articles/102...
February 19, 2025 at 12:35 AM
the version of record (VoR) of our most recent paper has been published @elife.bsky.social! 🎉🥳 🧪
elifesciences.org/articles/102...
elifesciences.org/articles/102...
Reposted by Ahmed Balboula
Check out our latest paper in Science Advances, in which we built a constriction-based microfluidic device to measure the deformability of oocytes to assess their mechanical properties with minimal impact.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Noninvasive characterization of oocyte deformability in microconstrictions
A microfluidic measurement method translates oocyte mechanical characterization into oocyte quality assessment.
www.science.org
February 20, 2025 at 7:11 AM
Check out our latest paper in Science Advances, in which we built a constriction-based microfluidic device to measure the deformability of oocytes to assess their mechanical properties with minimal impact.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Ahmed Balboula
Check out our super cool paper on aneuploidy in cells lacking Bub3. Congratulations to fantastic student Pallavi Gadgil and alum Olivia Ballew. journals.plos.org/plosgenetics...
Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3
Author summary Accurate chromosome segregation is crucial for the proper development of all living organisms. Errors in chromosome segregation can lead to aneuploidy, characterized by an abnormal numb...
journals.plos.org
February 21, 2025 at 6:41 PM
Check out our super cool paper on aneuploidy in cells lacking Bub3. Congratulations to fantastic student Pallavi Gadgil and alum Olivia Ballew. journals.plos.org/plosgenetics...