In this fantastic collaborative project with colleagues from Norway, @tu-dortmund.bsky.social @au.dk @uni-saarland.de, our outstanding PhD student @mkupjetz.bsky.social has shed light on distinct kynurenine pathway patterns in persons with #multiplesclerosis.

www.neurology.org/doi/10.1212/...

Welchen Einfluss hat Sport auf unsere Gesundheit? Lassen sich Immunzellen durch gezieltes Training beeinflussen? Kann man Sport sogar MS-Patienten Linderung verschaffen? Daran forschen Prof. Philipp Zimmer vom Institut für Sport und Sportwissenschaft & sein Team. www.youtube.com/watch?v=h58Y...

Check out our new paper now out in Acta Physiologica on the tryptophan metabolite 3-HAA in the aging and exercise context 👇
@50823zimmer.bsky.social @davidwalzik.bsky.social

onlinelibrary.wiley.com/doi/full/10....

This week in #Science #Immunology: researchers @ @helsinki.fi characterize #immune landscape of deep cervical #LymphNodes in newly diagnosed untreated patients w #MultipleSclerosis! Authors uncover several lines of evidence strengthening possible link btw #MS & Epstein–Barr virus ( #EBV ) infection!

Happy to share our new preprint, where we investigate the impact of acute exercise on the proteome of immune cell! Comparing high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE), we found numerous proteins that were differentially expressed in PBMCs. (1/12)

Acute exercise rewires the proteomic landscape of human immune cells https://www.medrxiv.org/content/10.1101/2025.01.30.25321196v1

While first countries blacklisted MDPI for their unserious and harmful publishing culture, German universities signed contracts with this china hosted predator publisher…what a waste of tax payer money!

www.mdpi.com/about/announ...

And there is this.... bsky.app/profile/carl...

Scientific publishing cannot be free but an annual $2.5 billion seems excessive to me

Finding the right journal is crucial and may influence careers! Of note first countries have blacklisted some publishers. A must read for all PIs, Post Docs and PhD Students:

direct.mit.edu/qss/article/...

Unbelievable to see our second @BrainBehavImm paper out in 2024🍾 @S_Proschinger @SergenBelen @maritschlagheck @TU_Dortmund and @SpohoKoeln 💪 Here we show that multimodal exercise training provokes Natalizumab-like effects in MS:
sciencedirect.com/science/articl…

How does exercise exert preventive and therapeutic effects in different diseases? What is the molecular basis of these effects and how are exercise signals mediated on a cellular level? A 🧵on our lates review in Signal Transduction and Targeted Therapy:
(1/13)

Thanks a lot to @50823zimmer.bsky.social and @niklasjoisten.bsky.social for the great supervision and input along the way and to Tiffany for the endless hours discussing mechanistic details! Cheers!🥂 (13/13)

As always this project would not have been possible without the help of numerous collaborators. A special thanks to @50823zimmer.bsky.social , Alan Metcalfe and @niklasjoisten.bsky.social who planned and conducted the trials and to Alexander Schenk, who performed hundreds of PCRs. (12/13)

6/ Writing or reviewing a manuscript? Watch out for these ten common statistical mistakes 👇
https://elifesciences.org/articles/48175?utm_source=bluesky&utm_medium=social&utm_campaign=organic

Recently, I have been on a grant review panel and a few members judged applications by the PI’s H index and impact factor of the previous papers - I objected. What has that to do with the strength of the proposed project?