Laure Bindels
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laurebindels.bsky.social
Laure Bindels
@laurebindels.bsky.social

Interested in the gut microbiota-host crosstalk in cancer and associated cachexia | Associate professor at @UCLouvain | Senior Editor at @microbiomej.bsky.social | Views are my own.

Biology 52%
Public Health 25%

Reposted by Laure B. Bindels

Jana Seifert, Julia Oh, Yongqi Shao, Markus Hilty, Purnima Kumar, Falk Hildebrand, Connie Lovejoy, Paul Wigley, Ke Yu, Meiling Zhang, Tong Zhang, Jens Walter, Mahesh Desai, Sharon Huws, Lynn M. Schriml, Jacques Ravel, W. Florian Fricke, Emiley Eloe-Fadrosh, Charles Lee, Thomas Clavel

We think that such efforts are essential to push the boundaries of our knowledge on microbiomes in a concerted, international effort.

If your manuscript fit these expectations, please submit it to Microbiome ! @microbiomej.bsky.social

With Joy Watts, Kevin Theis, Víctor Carrion, Adam Ossowicki,

Manuscripts need to meet high standards of language accuracy, quality of microbiome analyses, and data and protocol availability, including detailed reporting of wet-lab and in silico protocols, all of which can critically enhance transparency and reproducibility.

We take the opportunity to clarify our expectations for the articles submitted to the journal. At Microbiome, we are seeking studies that provide either new mechanistic insights into the role of microbiomes in health and environmental systems or substantial conceptual or technical advances.

New editorial at Microbiome 🦠 !
Co-authored by the Senior Editors, it aims to highlight current challenges in the field of environmental and host-associated microbiome research and provides a blueprint for contemporary studies of the microbiomes.
microbiomejournal.biomedcentral.com/articles/10....
A blueprint for contemporary studies of microbiomes - Microbiome
This editorial piece co-authored by the Senior Editors at Microbiome aims to highlight current challenges in the field of environmental and host-associated microbiome research. We also take the opport...
microbiomejournal.biomedcentral.com

Reposted by Laure B. Bindels

The Education Committee of the @CancerCachexia Society invites you to our seminar on February 12 at 12:00 pm EST with Anthony Coll of University of Cambridge, UK.
Seminars are open to everyone, please share!
See cancercachexiasociety.org for link.

Reposted by Laure B. Bindels

The Education Committee of the @CancerCachexia Society invites you to our seminar on February 12 at 12:00 pm EST with Anthony Coll of University of Cambridge, UK.
Seminars are open to everyone, please share!
See cancercachexiasociety.org for link.

More broadly, our work demonstrates the interest and relevance of microbial activity measurements using stable isotopes, an approach currently underused in the microbiome field.

Altogether, this work highlights the contribution of the gut microbiota to bile acid dysmetabolism and the therapeutic interest of the secondary bile acid TDCA for hepatic cholesterol homeostasis in the context of cancer cachexia.

(iii) administration of one of these bile acids, the taurodeoxycholic acid (TDCA), counteracted muscle atrophy (in vitro) 💪 and improved cholesterol homeostasis (in vivo).

In this manuscript, we established that (i) secondary bile acids are reduced in 3 mouse models of cancer cachexia, (ii) these alterations ensue from an altered bacterial metabolism of bile acids 🦠and

🎉New article from our team demonstating that a #microbiota derived #bileacid improves hepatic #cholesterol levels in mice with cancer #cachexia! Congratulations to Morgane Thibaut & Martin Roumain! Thanks to our collaborators, the FNRS and the @welbio.bsky.social www.tandfonline.com/doi/full/10....
The microbiota-derived bile acid taurodeoxycholic acid improves hepatic cholesterol levels in mice with cancer cachexia
Alterations in bile acid profile and pathways contribute to hepatic inflammation in cancer cachexia, a syndrome worsening the prognosis of cancer patients. As the gut microbiota impinges on host me...
www.tandfonline.com

Reposted by Laure B. Bindels

Do you want to start a PhD and study the transmission of the microbiome and alterations in neurological disorders? 🦠🖥️

We have a fully-funded position (deadline: 05/01/25)! All details: tinyurl.com/2b3sre8a
Feel free to get in touch for more info!

Indeed, thanks for the invitation! A new world for me 🌍
"Women full professors are 19% more likely than men at the same career stage to leave academia, as compared with 6% for women assistant professors and 10% for associates."
Women faculty feel ‘pushed’ from academia by poor workplace climate
The gender gap in faculty attrition worsens after tenure, according to a new study
www.science.org
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️

So how can we ever achieve #gender #equality?

We discuss various strategies in this #Cell Commentary

#WomeninSTEM

www.cell.com/cell/fulltex...
🧵 1/

Looking forward to it!

Reposted by Laure B. Bindels

The 8th Cancer Cachexia Conference will be hosted in Turin Italy, Sept 25-27, 2025

Congrats Aneesha for your position!

Reposted by Laure B. Bindels

I am hiring a Research Assistant microbiologist! We are new, expanding research group in the School of Microbiology, UCC and APC Microbiome Ireland in Cork studying anaerobic gut bacteria.
Deadline for applications 29th November. Apply here:
ore.ucc.ie
Job ID: 081111
University College Cork Vacancies
ore.ucc.ie