#venular
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sorengrubb.bsky.social
#Neurovasculature changes from the #arterial to the #venular end. Here I have tried to draw the #cell morphologies realistically. #Endothelialcells go from spindle shaped to rhombic shaped and #muralcells from #smoothmuscle to #pericytes. #Astrocytes same shape. www.sciencedirect.com/science/arti...
November 29, 2024 at 2:49 PM
haoyin.bsky.social
Human Native #CardiacValve can be vascularized (692/1246)

Prevalence
Aortic > Mitral > Tricuspid > Pulmonary

Venular, capillary & lymphatic vessels are more frequent than arteries

Corr. Age, BMI, Ethnicity, CAD, DM, Malignancy, Rheumatic fever
#CVpathol 2024
www.sciencedirect.com/science/arti...
March 2, 2024 at 12:29 PM
biorxivpreprint.bsky.social
Distinctive retinal peri-arteriolar versus peri-venular amyloid plaque distribution correlates with the cognitive performance https://www.biorxiv.org/content/10.1101/2024.02.27.580733v1
Distinctive retinal peri-arteriolar versus peri-venular amyloid plaque distribution correlates with the cognitive performance https://www.biorxiv.org/content/10.1101/2024.02.27.580733v1
Introduction: The vascular contribution to Alzheimer's disease (AD) is tightly connected to cognitiv
www.biorxiv.org
February 29, 2024 at 2:01 PM
biorxiv-pathology.bsky.social
Distinctive retinal peri-arteriolar versus peri-venular amyloid plaque distribution correlates with the cognitive performance https://www.biorxiv.org/content/10.1101/2024.02.27.580733v1
Distinctive retinal peri-arteriolar versus peri-venular amyloid plaque distribution correlates with the cognitive performance https://www.biorxiv.org/content/10.1101/2024.02.27.580733v1
Introduction: The vascular contribution to Alzheimer's disease (AD) is tightly connected to cognitiv
www.biorxiv.org
February 29, 2024 at 2:01 PM
kidneyboy.bsky.social
No oncotic or pressure gradient at venular side to push fluid back into the vessels. #renalresearchmeeting
December 4, 2024 at 5:43 AM
biorxivpreprint.bsky.social
Venular-centered thrombo-inflammation drives microvascular failure after arterial recanalization in acute mesenteric ischemia: a translational study https://www.biorxiv.org/content/10.64898/2026.01.08.698481v1
January 10, 2026 at 4:00 AM
haoyin.bsky.social
Atp13a5 marks mouse Brain/Spinal cord/Retina (not Heart/Liver/Kidney) #Pericyte (not arteriolar/venular SMC or perivascular fibroblast)

Atp13a5-2A-CreERT2-IRES-tdT brain pericyte reporter🐭 😎
#JNeurosci 2024

www.jneurosci.org/content/earl...
September 18, 2024 at 6:44 PM
dlingenfelter.bsky.social
Long Covid patients exhibited persistent endothelial dysfunction.

This was indicated by lower venular flicker-induced dilation (vFID), narrower central retinal artery equivalent (CRAE), and lower arteriolar-venular ratio (AVR).
link.springer.com/article/10.1...
Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation - Angiogenesis
Background Post-COVID-19 syndrome (PCS) is a lingering disease with ongoing symptoms such as fatigue and cognitive impairment resulting in a high impact on the daily life of patients. Understanding th...
link.springer.com
November 24, 2024 at 3:09 AM
sorengrubb.bsky.social
🧩 Summary:
✅ #Pericytes have #PrimaryCilia with an arterio-venular gradient🏳️‍🌈
✅ 🚶‍♀️🧠 ECs have primary #cilia, 🐁🧠 ECs don’t
✅ EC polarity aligns opposite to #BloodFlow 🧭
❔Lots of open questions about cilia’s role in #NeurovascularCoupling!
Read the full preprint: 🔗 www.biorxiv.org/content/10.1...
🧪🧵8/8
Graphical abstract showing gradient distribution of primary cilia in the mural cells. Primary cilium frequency and lengths are reversely proportional to smooth-muscle actin expression.
November 20, 2025 at 9:04 PM
shihcheng.bsky.social
Stroke recovery depends on revascularization. Key players: pericytes, venular SM cells & perivascular fibroblasts act as brain SPCs, aiding vessel regen. #StrokeRecovery PMID:39962273, Nat Neurosci 2025, @NatureNeuro https://doi.org/10.1038/s41593-025-01872-y 🧪
March 2, 2025 at 10:10 AM
klb888.bsky.social
And that intrarenal doppler is a more useful gauge of the effects of right heart disease, compared with pressure measurements - because doppler factors in the RA compliance and the venular compliance.(did I get that right?)
May 22, 2025 at 4:52 PM
johanduchene.bsky.social
Why are ACKR1+ intraplaque neovessels key in atherosclerosis?

These venular vessels express CXCL12 that attracts CD8+ T cells via CXCR4 in the plaque

This may unlock new cardiovascular therapy #Atherosclerosis #Chemokines

Read our study here 👇👇👇
www.ahajournals.org/doi/10.1161/...
Representative images showing intraplaque ACKR1+ neovessels (ACKR1, blue; CD31, green) producing CXCL12 (red) in human atherosclerotic plaque.
February 25, 2025 at 5:54 PM
biorxiv-pathology.bsky.social
Venular-centered thrombo-inflammation drives microvascular failure after arterial recanalization in acute mesenteric ischemia: a translational study https://www.biorxiv.org/content/10.64898/2026.01.08.698481v1
January 10, 2026 at 4:00 AM
sorengrubb.bsky.social
📊 #Pericytes are frequently ciliated in both 🐁 and 🚶‍♀️🧠—but mostly near #venules and venous-end #capillaries.
Venular mural cells: up to 90% ciliated in 🐁 datasets!
Arteriolar mural cells: almost none.
Why this gradient? Flow, pressure, permeability?
🧪🧵2/8
(d) Percent distribution of primary cilia in MCs after microvascular stratification into pial and parenchymal vessels, including 1-3rd order capillaries from the MICrONS (mouse visual cortex), CA1 (mouse hippocampus), and h01 (human cortex) datasets. Note that neither CA1 nor h01 contain any pial vessels. (e) Lengths of MC primary cilia in pial and parenchymal vessels, including 1-3rd order capillaries MCs from MICrONS.
November 20, 2025 at 9:04 PM
nordvvind.bsky.social
Und das nur, weil der Karpaltunnel etwas enger geworden ist. Ridelagh beobachtet:
“Interference with venular flow was observed already at a pressure of 20 to 30 mmHg” Mikro­zirkulations­störungen erhöhen Metaboliten-Stau und initiieren axonale Schädigung.
September 21, 2025 at 4:16 PM