Photogranules are phototrophic microbial aggregates varying from 200 µm to millimeters in size (1). They represent a candidate biomass for future wastewater treatment (2). They consist of syntrophical...

Key message Scalable moss bioreactors enable the production of high-quality recombinant prolyl-hydroxylated human collagen without heterologous P4H expression, offering a sustainable and vegan alterna...

**Abstract:** This research proposes a novel, data-driven approach to optimizing *Chlorella vulgaris* cultivation and lipid extraction for enhanced bio-diesel production. The system utilizes a Multi-modal Data Ingestion & Normalization Layer, a Semantic & Structural Decomposition Module, and a Multi-layered Evaluation Pipeline to dynamically adjust nutrient levels within photobioreactors and model lipid extraction efficiency. By employing a Recursive Quantum-Causal Pattern Amplification approach – synthesizing existing algal cultivation and extraction technologies with advanced data processing – we achieve a projected 25% increase in bio-diesel yield compared to conventional methods, significantly reducing production costs and improving environmental sustainability.

Collagens are structural proteins of the extracellular matrix essential for skin elasticity and integrity. They are widely used in dietary supplements and cosmetics. Conventional collagens of animal o...

Recharge your body naturally with PhycoSci X20, a premium spirulina-based dietary supplement packed with antioxidant-rich phycocyanin. 💧 Cultivated in pure photobioreactors and extracted through Xelliss’ exclusive EPNA process, it helps combat fatigue, boost vitality, and strengthen immunity. Experience clean, plant-powered energy and cellular protection — where science meets nature for optimal well-being every day. 🌿

Recharge your vitality with the PhycoSci X20 Kit 🌿 — a premium aqueous spirulina supplement rich in phycocyanin, nature’s powerful antioxidant. Each kit includes 2 bottles (2×250 ml) cultivated in photobioreactors for maximum purity and potency. Join Subscribe & Save to enjoy 30 % off, earn ZinoCash monthly, and keep your energy, immunity, and recovery on autopilot — backed by science, powered by nature. 💧

Recharge your vitality with the PhycoSci X20 Kit 🌿 — a premium aqueous spirulina supplement rich in phycocyanin, nature’s powerful antioxidant. Each kit includes 2 bottles (2×250 ml) cultivated in photobioreactors for maximum purity and potency. Join Subscribe & Save to enjoy 30 % off, earn ZinoCash monthly, and keep your energy, immunity, and recovery on autopilot — backed by science, powered by nature. 💧

Recharge your body naturally with PhycoSci X20, a premium spirulina-based dietary supplement packed with antioxidant-rich phycocyanin. 💧 Cultivated in pure photobioreactors and extracted through Xelliss’ exclusive EPNA process, it helps combat fatigue, boost vitality, and strengthen immunity. Experience clean, plant-powered energy and cellular protection — where science meets nature for optimal well-being every day. 🌿

Collagens are important structural proteins of the extracellular matrix that are essential for skin elasticity and integrity and are widely used in dietary supplements and cosmetics. Conventional coll...

Monolayer nanoparticle-covered liquid marbles (mNPc LMs), fabricated using a sol–gel SiO2 coating as the particle source, were developed as micro-photobioreactors (PBRs) for high-efficiency cyanobacte...

Four project partners trained in microalgae and photobioreactor design at Wageningen University, gaining skills to scale up solar fuel production.

Key message First production of virus-like particles as a vaccine candidate in a non-vascular plant. Abstract Virus-like particles (VLPs) are self-assembling nanoparticles composed of viral structural proteins which mimic native virions but lack viral DNA and infectivity. VLPs are a resourceful class of biopharmaceuticals applied as subunit vaccines or as delivery vehicles for drugs and nucleic acids. Similar to viruses, VLPs are diverse in structure, composition, and assembly, requiring a tailored production platform aligned with the intended application. The moss plant Physcomitrella (Physcomitrium patens) is an emerging expression system offering humanized N-glycosylation, scalability, and adaptability to existing industry settings. Here, we used Physcomitrella to produce human papillomavirus (HPV) 16 VLPs. HPV VLPs are composed of the major structural protein L1 and are used as vaccines against HPV infections which are the main causal agent of cervical and other anogenital cancers. We characterized Physcomitrella chloroplast transit peptides, which we used for targeting of moss-produced L1 to chloroplasts, leading to higher recombinant protein yield compared to nuclear or cytoplasmic localization. We confirmed subcellular localization with confocal laser scanning microscopy and found L1 to accumulate within the chloroplast stroma. Production in 5-L photobioreactors yielded over 0.3 mg L1 per gram fresh weight. We established a purification protocol for moss-produced L1 using a combination of ammonium sulphate precipitation and cation exchange chromatography. Purified samples were subjected to a controlled dis- and reassembly, yielding fully assembled HPV-16 L1 VLPs. This is the first report of production, purification, and assembly of VLPs in a non-vascular plant.

Key message First production of virus-like particles as a vaccine candidate in a non-vascular plant. Abstract Virus-like particles (VLPs) are self-assembling nanoparticles composed of viral structural...

Astronauts exploring the moon will need all the help they can get, and scientists have spent lots of time and plenty of money coming up with different systems to do so. Two of the critical needs of any long-term lunar mission are food and oxygen, both of which are expensive to ship to the moon from Earth.

Astronauts exploring the Moon will need all the help they can get, and scientists have spent lots of time and plenty of money coming up with different systems