We are extremely grateful to the #maleCNS team, incl. @janelia-flyem.bsky.social, @jefferis.bsky.social and lab, and many, many others. Backstory >> bsky.app/profile/jeff... Website >> male-cns.janelia.org

How do animals channel sensory information into motor pathways to generate flexible behavioral output? Excited to share a new preprint addressing this question by leveraging the new #maleCNS connectome, behavioral experiments, and in-vivo recordings: doi.org/10.64898/202.... A long🧵...

(3) We then show that female AOTU neurons are similar to their male counterparts, in terms of their LC10a connections and visual receptive field properties. These results argue that the core visual pursuit circuit has similar physiological properties in both sexes.

To highlight just a few of the newest features:

(1) With the new male connectome, we were able to perform comparative analyses of AOTU cells in males and females. We showed that, in both sexes, AOTU019 and AOTU025 are the key links between visual input (LC10a) and pre-motor outputs (DNs).

the broader Drosophila and neuroscience fields for all of the amazing previous work that allowed this to be possible!

To search across the wonderful new #malecns on your own, check out male-cns.janelia.org

Major thanks goes to our co-authors, Claire Managan, Marisa Dreher, Elizabeth Kim, Scott Miller, Katie Boone, Alice Robie, Adam Taylor, and @kristinmbranson.bsky.social, the #malecns team, as well as our amazing colleagues @hhmijanelia.bsky.social (in other labs and teams) for their support and… 10/

#malecns (collaborative effort with @janelia-flyem.bsky.social @camzoology.bsky.social @mrclmb.bsky.social @jefferis.bsky.social @stuartberg.bsky.social @beckett14.bsky.social @mmcosta.bsky.social Philipp Schlegel and others) split P1/pC1x into 48 cell types based on morphology and connectivity. 3/

Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...

We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10

And here's the official announcement from our Janelia collaborators with a fantastic visualisation from @philiphubbard.bsky.social. See more at male-cns.janelia.org/media. Downloads are humming and we have solved the first data access queries. Happy exploring! #drosophila #connectomics #malecns.