The final lab test results have confirmed that bird flu was detected in two birds sent for testing from a dead flock of vultures found on the grounds of an Ohio school last month.

Officials don't know what caused gastrointestinal illness in 95 passengers and 9 crew on the Celebrity Eclipse in late December.

Spatial spread in Eurasia in 2020–2023 In summer 2020, HPAI H5 viruses were detected in North Asia (Russia, Kazakhstan)30,31, with viruses likely originating from North Africa or the Middle East25,32,33 (Fig. 1). North Asia has likely been acting as a...

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Highly pathogenic avian influenza (HPAI) is circulating once again this winter and has already been confirmed in New Jersey in Canada geese, Snow geese, and Bald eagles. This virus primarily […]

Seasonal influenza viruses evade host immunity through rapid antigenic evolution. Antigenicity is assessed by serological assays and typically visualized as antigenic maps, which represent antigenic d...

Since 2021, highly pathogenic avian influenza viruses (HPAIV) belonging to H5N1 clade 2.3.4.4b have caused high mortality in North American wild birds and poultry. In 2025, a new D1.1 genotype caused two human deaths and host-switched to dairy cattle. However, the evolutionary origins and dynamics of D1.1 have not been fully characterized. Here, our phylogenetic analysis of 17,516 H5N1 genome sequences uncovers how D1.1 introduced a major shift in the antigenic diversity and ecology of the H5N1 epizootic in North America. D1.1 is the first major H5N1 genotype to (a) emerge in the Pacific flyway and spread west-to-east faster than any prior genotype; (b) antigenically shift via reassortment with the North American N1 segment, displacing the previously fixed Eurasian N1; and (c) transmit to a broader range of host species than any H5N1 genotype to date, introducing mammalian adaptations. ### Competing Interest Statement The authors have declared no competing interest. Research Foundation - Flanders, https://ror.org/03qtxy027, G098321N, G0E1420N European Union Horizon 2023 RIA project LEAPS, 101094685 DURABLE EU4Health project 02/2023-01/2027, 101102733 Fonds National de la Recherche Scientifique, F.4515.22 European Union Horizon 2020 project MOOD, 874850

CD388 is an investigational long-acting, strain-agnostic antiviral agent currently in Phase 3, designed to prevent influenza infection in individuals at higher risk of influenza complications Acquisit...

A dog in Alberta died in November after being exposed to highly pathogenic avian influenza. It's the second confirmed fatal case of avian flu in a domestic dog in Canada, with the first being reported...

Bird flu has been rampaging through wildlife and farm animals worldwide. Will it make the long-feared jump to humans?

The Canadian Wildlife Health Cooperative is having the Canadian Food Inspection Agency conduct its own tests before 100 per cent confirming the virus as the culprit for the crows death.

The Canadian Wildlife Health Cooperative is having the Canadian Food Inspection Agency conduct its own tests before 100 per cent confirming the virus as the culprit for the crows death.