⏰ Last chance to save $250! Register by Dec 18 (11:59pm MST) for the Keystone Symposium on Stem Cell Models in Embryology. Join cutting-edge discussions on SCBEMs and their translational potential.
hubs.la/Q03YlPvV0

#KSEmbryology26 #embryology @jun-wu-lab.bsky.social @ebisuyamiki.bsky.social

More #gastruloid studies. Benchmarking correlations between RNA/proteins w/ acquiring information @ phosphorylation across #mouse & #human www.biorxiv.org/content/10.1...
Also looking at #Disease modelling. Fantastic #TourDForce Valuable bench marking and insight
@dschweppe.bsky.social #SCBEMs

Stem-cell-based embryo models (SCBEMs), including Gastruloid models, have pioneered a new avenue in the field of experimental developmental biology. However, the existing human gastruloid models primarily capture posterior embryonic fates. (2/n)

Furthermore, it is this work that enabled research into early human development, derivation of pluripotent stem cells and Stem Cell based Embryo Models #SCBEMs.

Keystone symposia on stem-cell-based embryo models (SCBEMs). Join us in discussing the development, measurement, and manipulation of SCBEMs in California in Feb 2026!
www.keystonesymposia.org/conferences/...

Scholarship/ShortTalk Deadline: Oct 21
Early Registration Deadline: Dec 18 (Save $200!)

COMMENT: Professor Emma Cave writes about the regulation of human SCBEM and how there are good reasons to distinguish them from embryos. Read the article in BioNews: www.progress.org.uk/human-stem-c...

#SCBEMs #ELS #regulation #stemcells #embryo #humandevelopment @emmacave.bsky.social

EVENT REVIEW: Dr Güneş Taylor reviews a recent webinar which presented recommendations for oversight of SCBEMs to allow us to study the intricacies of human embryonic development: www.progress.org.uk/event-review...
#SCBEM #regulation #stemcells #embryomodels #embryoresearch #embryos @isscr.org

New in Journal of Law & the Biosciences: I argue for separate regulatory pathways for embryos and stem cell-based embryo models (SCBEMs).
Paper builds on the 2024 Nuffield Council on Bioethics WG I chaired.
#SCBEMs #bioethics #lifesciences
🔗 academic.oup.com/jlb/article-...

I like to think that in my field, stem cell based embryo models ( #SCBEMs), states will follow the initiative of the UK Code of Practice, & its impending governance framework.
In conceiving it, we had Asilomar (its positive impact as well as its limitations) firmly in mind.

Let me know how we did.

SCBEMs lack critical components of embryonic development, including the notochord: a defining feature of chordates that patterns surrounding tissues. Modeling single cell transcription of the notochord leads to SCBE modelling of patterning in vitro.

www.nature.com/articles/s41...

This is a very welcome contribution to the UK’s ongoing discourse on the governance of #SCBEMs.
I look forward to discussing this and related issues with at the Progress Educational Trust’ Annual Conference next week, 4 December.