Nucleotide-bound crystal structures of SARS-CoV-2 NSP13 in ADP- and ATP-bound states revealed that crystal packing influences NSP13 by stabilizing the nucleotide-binding site
#SARSCoV2 #NSP13Helicase #NucleotideBindingSite doi.org/10.1107/S205...
#SARSCoV2 #NSP13Helicase #NucleotideBindingSite doi.org/10.1107/S205...
August 18, 2025 at 1:16 PM
Nucleotide-bound crystal structures of SARS-CoV-2 NSP13 in ADP- and ATP-bound states revealed that crystal packing influences NSP13 by stabilizing the nucleotide-binding site
#SARSCoV2 #NSP13Helicase #NucleotideBindingSite doi.org/10.1107/S205...
#SARSCoV2 #NSP13Helicase #NucleotideBindingSite doi.org/10.1107/S205...
Patrick Kloskowski et al.: Nucleotide-bound crystal structures of the SARS-CoV-2 helicase NSP13 ##SARSCoV2##NSP13Helicase##NucleotideBindingSite@unigoettingen...##IUCrhttps://journals.iucr.org/paper?S2053230X25005266
Nucleotide-bound crystal structures of the SARS-CoV-2 helicase NSP13
Nucleotide-bound crystal structures of SARS-CoV-2 NSP13 capture a state immediately following ATP hydrolysis and reveal how crystal packing can affect structure-based drug design targeting NSP13.
journals.iucr.org
July 11, 2025 at 12:00 AM
Patrick Kloskowski et al.: Nucleotide-bound crystal structures of the SARS-CoV-2 helicase NSP13 ##SARSCoV2##NSP13Helicase##NucleotideBindingSite@unigoettingen...##IUCrhttps://journals.iucr.org/paper?S2053230X25005266