This #STTT study shows #MDH2 as a potential #TherapeuticTarget that alleviates aging phenotypes by enhancing methionine cycle flux & restoring age-related #HistoneMethylation changes, highlighting #Glibenclamide as an effective #AntiAging agent.

#OpenAccess: doi.org/10.1038/s413...

Epigenetics Update - KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition bit.ly/3Q9xlYV

#Epigenetics #HIstoneMethylation
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Discover the Paired-tag breakthrough at epigenome.us