Does Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Represent a Poly-Herpesvirus Post-Virus Infectious Disease?
by Maria Eugenia Ariza, Irene Mena Palomo and Marshall V. Williams
(December 2025)
#ME/CFS #HHVs #dUTPase
by Maria Eugenia Ariza, Irene Mena Palomo and Marshall V. Williams
(December 2025)
#ME/CFS #HHVs #dUTPase
www.mdpi.com
January 6, 2026 at 5:39 PM
Does Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Represent a Poly-Herpesvirus Post-Virus Infectious Disease?
by Maria Eugenia Ariza, Irene Mena Palomo and Marshall V. Williams
Institute of Brain, Behavior and Immunology (IBBI), The Ohio State University
#ME/CFS #HHVs
by Maria Eugenia Ariza, Irene Mena Palomo and Marshall V. Williams
Institute of Brain, Behavior and Immunology (IBBI), The Ohio State University
#ME/CFS #HHVs
www.mdpi.com
December 22, 2025 at 12:38 AM
‘HHVs are nearly ubiquitous neurotropic viruses that establish latency after initial infection & are intermittently reactivated in contexts such as stress or immunosuppression…
[in] meta-analysis..of the HHVs, the highest odds of ME/CFS were associated with HHV6 & HHV7 & particularly.. co-infection’
[in] meta-analysis..of the HHVs, the highest odds of ME/CFS were associated with HHV6 & HHV7 & particularly.. co-infection’
October 25, 2025 at 1:29 AM
‘HHVs are nearly ubiquitous neurotropic viruses that establish latency after initial infection & are intermittently reactivated in contexts such as stress or immunosuppression…
[in] meta-analysis..of the HHVs, the highest odds of ME/CFS were associated with HHV6 & HHV7 & particularly.. co-infection’
[in] meta-analysis..of the HHVs, the highest odds of ME/CFS were associated with HHV6 & HHV7 & particularly.. co-infection’
‘HHVs are nearly ubiquitous neurotropic viruses that establish latency after initial infection & are intermittently reactivated in contexts such as stress or immunosuppression…
[in] meta-analysis..of the HHVs, the highest odds of ME/CFS were associated with HHV6 & HHV7 & particularly.. co-infection’
[in] meta-analysis..of the HHVs, the highest odds of ME/CFS were associated with HHV6 & HHV7 & particularly.. co-infection’
October 25, 2025 at 1:28 AM
‘HHVs are nearly ubiquitous neurotropic viruses that establish latency after initial infection & are intermittently reactivated in contexts such as stress or immunosuppression…
[in] meta-analysis..of the HHVs, the highest odds of ME/CFS were associated with HHV6 & HHV7 & particularly.. co-infection’
[in] meta-analysis..of the HHVs, the highest odds of ME/CFS were associated with HHV6 & HHV7 & particularly.. co-infection’
Fresh of publication in Nature
HLA and pathogens in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and other post-infection conditions
www.nature.com/articles/s41...
#ME/CFS #HHVs #HLA
HLA and pathogens in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and other post-infection conditions
www.nature.com/articles/s41...
#ME/CFS #HHVs #HLA
HLA and pathogens in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and other post-infection conditions - Scientific Reports
Scientific Reports - HLA and pathogens in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and other post-infection conditions
www.nature.com
October 24, 2025 at 6:08 PM
Fresh of publication in Nature
HLA and pathogens in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and other post-infection conditions
www.nature.com/articles/s41...
#ME/CFS #HHVs #HLA
HLA and pathogens in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and other post-infection conditions
www.nature.com/articles/s41...
#ME/CFS #HHVs #HLA
This can still be a subgroup finding in a subpopulation of pwME. We have case histories of familial cases of ME where multiple members have issues with HHVs, as well as Borrelia and now COV-19.
October 24, 2025 at 5:35 PM
This can still be a subgroup finding in a subpopulation of pwME. We have case histories of familial cases of ME where multiple members have issues with HHVs, as well as Borrelia and now COV-19.
#TheTwen2ie5
#41 (Day 10)
What Goes Around (Comes Around)
Robert Finley
From "Black Bayou
2023 (US)
Here's a 71-year old guy who still meets the Ice Spice clause! Finley started recording in 2016 after playing semi-pro locally for decades. Absolutely smokin' blues!
www.youtube.com/watch?v=HhVs...
#41 (Day 10)
What Goes Around (Comes Around)
Robert Finley
From "Black Bayou
2023 (US)
Here's a 71-year old guy who still meets the Ice Spice clause! Finley started recording in 2016 after playing semi-pro locally for decades. Absolutely smokin' blues!
www.youtube.com/watch?v=HhVs...
Robert Finley - "What Goes Around (Comes Around)" [Official Music Video]
YouTube video by Easy Eye Sound
www.youtube.com
October 10, 2025 at 1:33 AM
#TheTwen2ie5
#41 (Day 10)
What Goes Around (Comes Around)
Robert Finley
From "Black Bayou
2023 (US)
Here's a 71-year old guy who still meets the Ice Spice clause! Finley started recording in 2016 after playing semi-pro locally for decades. Absolutely smokin' blues!
www.youtube.com/watch?v=HhVs...
#41 (Day 10)
What Goes Around (Comes Around)
Robert Finley
From "Black Bayou
2023 (US)
Here's a 71-year old guy who still meets the Ice Spice clause! Finley started recording in 2016 after playing semi-pro locally for decades. Absolutely smokin' blues!
www.youtube.com/watch?v=HhVs...
The original ME was deemed most likely to be [Enterovirus betacoxsackie (EV-B), the current name for Coxsackie Bs, Echoviruses, and some others]. The modern variations of ME/CFS include EVs, HHVs, and other infections as well as non-infectious onsets. In both cases, it can involve metabolic effects.
August 29, 2025 at 11:22 AM
The original ME was deemed most likely to be [Enterovirus betacoxsackie (EV-B), the current name for Coxsackie Bs, Echoviruses, and some others]. The modern variations of ME/CFS include EVs, HHVs, and other infections as well as non-infectious onsets. In both cases, it can involve metabolic effects.
Unfortunately HHVs cannot be permanently eradicated once someone has been infected, but only put into a state of latency: pmc.ncbi.nlm.nih.gov/articles/PMC...
Herpesvirus latency
Herpesviruses infect virtually all humans and establish lifelong latency and reactivate to infect other humans. Latency requires multiple functions: maintaining the herpesvirus genome in the nuclei of...
pmc.ncbi.nlm.nih.gov
February 4, 2025 at 5:01 PM
Unfortunately HHVs cannot be permanently eradicated once someone has been infected, but only put into a state of latency: pmc.ncbi.nlm.nih.gov/articles/PMC...
It's also a reminder of the origins of the hybrid condition and origins of the originals. ME was originally thought to be induced by polioviruses, which it would have been but for "PV4" being named Coxsackie virus in 1948. CFS was associated with EBV and other HHVs. MECFS is broader, incl. EV+HHV.
January 23, 2025 at 4:21 AM
It's also a reminder of the origins of the hybrid condition and origins of the originals. ME was originally thought to be induced by polioviruses, which it would have been but for "PV4" being named Coxsackie virus in 1948. CFS was associated with EBV and other HHVs. MECFS is broader, incl. EV+HHV.
A good review article - #MECFS is it #medicallyunexplained or not looking deep enough. Glial dysfunction, brain perfusion abn, reactivation of EBV/HHVs, brian slump, reduced brainstem mobility etc
www.frontiersin.org/journals/cel...
www.frontiersin.org/journals/cel...
November 20, 2024 at 10:53 AM
A good review article - #MECFS is it #medicallyunexplained or not looking deep enough. Glial dysfunction, brain perfusion abn, reactivation of EBV/HHVs, brian slump, reduced brainstem mobility etc
www.frontiersin.org/journals/cel...
www.frontiersin.org/journals/cel...
New preprint study following >1100 hospitalized patients for a year — they found reactivation of herpesviruses (EBV, CMV, HHVs), enteroviruses, and anneloviruses during the acute phase of Covid infection (and decreasing thereafter), correlating with disease severity.
Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19 https://www.biorxiv.org/content/10.1101/2024.11.14.622799v1
Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19 https://www.biorxiv.org/content/10.1101/2024.11.14.622799v1
Chronic viral infections are ubiquitous in humans, with individuals harboring multiple latent viruse
www.biorxiv.org
November 17, 2024 at 3:52 PM
New preprint study following >1100 hospitalized patients for a year — they found reactivation of herpesviruses (EBV, CMV, HHVs), enteroviruses, and anneloviruses during the acute phase of Covid infection (and decreasing thereafter), correlating with disease severity.
Dawn Butler recent highlights:
Black supremacist poem:
www.youtube.com/watch?v=hHVs...
Black supremacist poem REPEATED in House of Commons:
x.com/DawnButlerBr...
And now resharing the Kemi Badenoch blackface comment.
🤡🤡🤡🤡🤡🤡🤡🤡🤡
Disgusting levels of racism from Labour Party.
#UKPolitics #Labour
Black supremacist poem:
www.youtube.com/watch?v=hHVs...
Black supremacist poem REPEATED in House of Commons:
x.com/DawnButlerBr...
And now resharing the Kemi Badenoch blackface comment.
🤡🤡🤡🤡🤡🤡🤡🤡🤡
Disgusting levels of racism from Labour Party.
#UKPolitics #Labour
November 2, 2024 at 8:06 PM
Dawn Butler recent highlights:
Black supremacist poem:
www.youtube.com/watch?v=hHVs...
Black supremacist poem REPEATED in House of Commons:
x.com/DawnButlerBr...
And now resharing the Kemi Badenoch blackface comment.
🤡🤡🤡🤡🤡🤡🤡🤡🤡
Disgusting levels of racism from Labour Party.
#UKPolitics #Labour
Black supremacist poem:
www.youtube.com/watch?v=hHVs...
Black supremacist poem REPEATED in House of Commons:
x.com/DawnButlerBr...
And now resharing the Kemi Badenoch blackface comment.
🤡🤡🤡🤡🤡🤡🤡🤡🤡
Disgusting levels of racism from Labour Party.
#UKPolitics #Labour
Utterly depressing that the only place the Dawn Butler racist poem video has gained attraction is on GB News:
www.youtube.com/watch?v=BU2P...
And this is dangerous because it opens the door wide for “two tier policing“ rhetoric again.
www.youtube.com/watch?v=hHVs...
#UKPolitics
www.youtube.com/watch?v=BU2P...
And this is dangerous because it opens the door wide for “two tier policing“ rhetoric again.
www.youtube.com/watch?v=hHVs...
#UKPolitics
Labour MP posts murderers and rapists in SHOCKING black history month post: 'No APOLOGY whatsoever!'
YouTube video by GBNews
www.youtube.com
October 5, 2024 at 11:09 AM
Utterly depressing that the only place the Dawn Butler racist poem video has gained attraction is on GB News:
www.youtube.com/watch?v=BU2P...
And this is dangerous because it opens the door wide for “two tier policing“ rhetoric again.
www.youtube.com/watch?v=hHVs...
#UKPolitics
www.youtube.com/watch?v=BU2P...
And this is dangerous because it opens the door wide for “two tier policing“ rhetoric again.
www.youtube.com/watch?v=hHVs...
#UKPolitics
I know what EBV is 😂. Mostly from research frankly (HHV immune response augmentation using CRISPR).
I’d argue that other HHVs may be even more apt than HHV4 (aka EBV), but that’s neither here nor there and gets more nerdy and less funny.
I’d argue that other HHVs may be even more apt than HHV4 (aka EBV), but that’s neither here nor there and gets more nerdy and less funny.
November 17, 2023 at 11:31 AM
I know what EBV is 😂. Mostly from research frankly (HHV immune response augmentation using CRISPR).
I’d argue that other HHVs may be even more apt than HHV4 (aka EBV), but that’s neither here nor there and gets more nerdy and less funny.
I’d argue that other HHVs may be even more apt than HHV4 (aka EBV), but that’s neither here nor there and gets more nerdy and less funny.
riiiiight????!! it's just nuts. and we used to think EBV was just "the kissing disease." HHVs are wiley little bastards.
September 11, 2023 at 8:03 AM
riiiiight????!! it's just nuts. and we used to think EBV was just "the kissing disease." HHVs are wiley little bastards.