#GutConnectome🔁#BrainConnectome🧠
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rajansingh.bsky.social
📢Elegant study @gastroenterology.bsky.social 🆕🔥
Intestinal Epithelial #Serotonin as a Novel Target for Treating #DGBI & #Mood‼️ #GutConnectome🔁#BrainConnectome🧠#Serotonin
@karapedsgastrodoc.bsky.social @margolislabnyu.bsky.social
🎉
👉https://www.gastrojournal.org/article/S0016-5085(24)05751-2/fulltext
✳️The most recent advances into how the #GI tract modulates #EmotionalBehaviors ⏩A novel #gut-targeted therapeutic approach for mood modulation ⏩A new link in humans between in utero #SSRI exposure & #DGBI development👏 ▶️Targeted deletion of the #SERT in the intestinal epithelium reduced #anxiety & #depressive-like behaviors✨ ▶️Increased serotonin in the gut epithelium is #anxiolytic & anti-depressive which is mediated through #vagal signaling 🎯 ▶️Maternal #SSRI exposure is associated with a risk of developing #constipation in the first year of life⚡️
December 12, 2024 at 2:43 PM
rajansingh.bsky.social
Excellent review @naturerevmicro.bsky.social 🆕🔥
🚨Microbiota🦠–neuroepithelial signalling across the #Gut–#Brain axis‼️
#GutConnectome🔁#BrainConnectome🧠
👉 www.nature.com/articles/s41...
✅Most recent advances in pathways that connect the gut & brain🧠
#DGBIs #Neuropsychiatric health #Serotonin #GLP-1
✳️So much to learn in the field😇 ✅Most recent advances in pathways that connect the gut & brain🧠 ⏩Complex dialogue between microorganisms & neurons at intestinal #neuroepithelial interface👏 🎯#Microbial factors, #endocrine cells & neural mechanisms that govern Gut microbiota–Brain interactions💡 💊Potential of microbiota-based therapies targeting intestinal neuroepithelial pathways✨ #DGBIs #Neuropsychiatric health #GutSensory system #Serotonin #GLP-1
January 4, 2025 at 6:30 PM