Happy #FluorescenceFriday from these primary astrocytes grown on glass slides and robotically stained on the Biocare Oncore Pro X! 🧠🔬🧪
Cyan = GFAP
Royal Purple = ALDH1L1
Salmon = Nuclear Counterstain
Cyan = GFAP
Royal Purple = ALDH1L1
Salmon = Nuclear Counterstain
November 7, 2025 at 7:26 PM
Happy #FluorescenceFriday from these primary astrocytes grown on glass slides and robotically stained on the Biocare Oncore Pro X! 🧠🔬🧪
Cyan = GFAP
Royal Purple = ALDH1L1
Salmon = Nuclear Counterstain
Cyan = GFAP
Royal Purple = ALDH1L1
Salmon = Nuclear Counterstain
For #FluorescenceFriday - one of my favorites from the archives of a neuron ⚪ and astrocyte 🟢 co-culture. Image credit to Stephanie Page and former research assistant Beth Pattie 🧠🔬🧪
November 7, 2025 at 12:37 PM
For #FluorescenceFriday - one of my favorites from the archives of a neuron ⚪ and astrocyte 🟢 co-culture. Image credit to Stephanie Page and former research assistant Beth Pattie 🧠🔬🧪
Double posting for #FluorescenceFriday today, because I am in love w/ this particular astrocyte (marked w/ GFAP in 🔴) that is sitting in dorsal anterior cingulate cortex in the human 🧠. Image credit to Staff Scientist/image analyst Maddy Tippani and JHU grad student @shkwon-bcmbneuro.bsky.social 🔬🧪
October 24, 2025 at 2:35 PM
Double posting for #FluorescenceFriday today, because I am in love w/ this particular astrocyte (marked w/ GFAP in 🔴) that is sitting in dorsal anterior cingulate cortex in the human 🧠. Image credit to Staff Scientist/image analyst Maddy Tippani and JHU grad student @shkwon-bcmbneuro.bsky.social 🔬🧪
queria mt fzr uma marcação de iba-1, gfap e sinaptofisina do meu cérebrozinho pra mapear qnd eu atingir a gnose ou um alzheimer precoce
September 19, 2024 at 12:09 PM
queria mt fzr uma marcação de iba-1, gfap e sinaptofisina do meu cérebrozinho pra mapear qnd eu atingir a gnose ou um alzheimer precoce
Happy #WidefieldWednesday Bluesky!!
A new hashtag to appreciate all of the wonderful widefield #microscopy work shared here 🧪🧠🔬
Today we are sharing this photo of a primary #astrocyte grown on cover glass used in the study of #Parkinsons disease, imaged with a VS200 slide scanning microscope.
A new hashtag to appreciate all of the wonderful widefield #microscopy work shared here 🧪🧠🔬
Today we are sharing this photo of a primary #astrocyte grown on cover glass used in the study of #Parkinsons disease, imaged with a VS200 slide scanning microscope.
April 9, 2025 at 4:21 PM
Happy #WidefieldWednesday Bluesky!!
A new hashtag to appreciate all of the wonderful widefield #microscopy work shared here 🧪🧠🔬
Today we are sharing this photo of a primary #astrocyte grown on cover glass used in the study of #Parkinsons disease, imaged with a VS200 slide scanning microscope.
A new hashtag to appreciate all of the wonderful widefield #microscopy work shared here 🧪🧠🔬
Today we are sharing this photo of a primary #astrocyte grown on cover glass used in the study of #Parkinsons disease, imaged with a VS200 slide scanning microscope.
Enzym, das in unseren Zellen eine wichtige Rolle bei der Zellkommunikation und der Organisation von Zellmembranen spielt. Dieses Enzym hilft dabei, ein bestimmtes Molekül namens Phosphatidylinositol in eine andere Form umzuwandeln (Phosphatidylinositol-4-Phosphat, kurz PI4P). PI4P ist
December 30, 2024 at 10:26 PM
Enzym, das in unseren Zellen eine wichtige Rolle bei der Zellkommunikation und der Organisation von Zellmembranen spielt. Dieses Enzym hilft dabei, ein bestimmtes Molekül namens Phosphatidylinositol in eine andere Form umzuwandeln (Phosphatidylinositol-4-Phosphat, kurz PI4P). PI4P ist
Authors used Anti-GFAP mouse mono from #NeuroMab in their study. Including #RRIDs will make this less ambiguous.
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #OpenScience #STMpublishing
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #OpenScience #STMpublishing
www.biorxiv.org
July 28, 2025 at 12:00 PM
Authors used Anti-GFAP mouse mono from #NeuroMab in their study. Including #RRIDs will make this less ambiguous.
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #OpenScience #STMpublishing
SciScore made a table with this resource, see “Automated Services” module (download as csv, xml or #jats) #OpenScience #STMpublishing
This study analytically validated the MSD S-Plex® GFAP immunoassay for plasma and established age-stratified reference intervals in a healthy population. The assay demonstrated strong performance, with low variability and a wide measurement range.
October 8, 2025 at 7:26 PM
This study analytically validated the MSD S-Plex® GFAP immunoassay for plasma and established age-stratified reference intervals in a healthy population. The assay demonstrated strong performance, with low variability and a wide measurement range.
These findings suggest that NfL and GFAP elevations in mood disorders are minimal, contrasting with the large elevations in neurodegenerative disorders. This supports the use of these biomarkers in clinical settings to distinguish psychiatric from neurodegenerative causes
January 25, 2025 at 6:32 AM
These findings suggest that NfL and GFAP elevations in mood disorders are minimal, contrasting with the large elevations in neurodegenerative disorders. This supports the use of these biomarkers in clinical settings to distinguish psychiatric from neurodegenerative causes
Only NfL showed high stability after seven‑day delayed processing in venous and capillary serum and plasma in the multi‑disease discovery cohort despite a huge amount of haemolysis evident in the samples. GFAP was still correlated but clearly started to go down after 7 days delay.
July 10, 2025 at 4:42 PM
Only NfL showed high stability after seven‑day delayed processing in venous and capillary serum and plasma in the multi‑disease discovery cohort despite a huge amount of haemolysis evident in the samples. GFAP was still correlated but clearly started to go down after 7 days delay.
#fluorescencefriday Astrocytes double labeled for GFAP and HM3Dq-DREADD. Courtesy of Alycia Crooks PhD students in the lab. 🧪
June 6, 2025 at 2:35 PM
#fluorescencefriday Astrocytes double labeled for GFAP and HM3Dq-DREADD. Courtesy of Alycia Crooks PhD students in the lab. 🧪
Lysosomal function, resistance to stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant https://www.biorxiv.org/content/10.1101/2024.12.03.626547v1
Lysosomal function, resistance to stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant https://www.biorxiv.org/content/10.1101/2024.12.03.626547v1
Intermediate filaments are critical regulators of cell responses and organizers of cellular structur
www.biorxiv.org
December 4, 2024 at 1:31 PM
Lysosomal function, resistance to stress and repair are compromised by expression of the Alexander disease GFAP R239C mutant https://www.biorxiv.org/content/10.1101/2024.12.03.626547v1
Study uses quanterix for NfL and GFAP
March 17, 2025 at 3:54 PM
Study uses quanterix for NfL and GFAP
Positive for desmin, MyoD1, S100 protein and GFAP.
April 2, 2025 at 7:44 PM
Positive for desmin, MyoD1, S100 protein and GFAP.
#PublicaSalutIB Son Espases e @idisba.bsky.social han participado en el análisis del impacto presupuestario de los biomarcadores GFAP y UCH-L1 en el TCE leve en España https://www.infosalut.com/es/investigacio/estudis-i-projectes/17854 https://doi.org/10.3390/jcm14124095
September 19, 2025 at 6:01 PM
#PublicaSalutIB Son Espases e @idisba.bsky.social han participado en el análisis del impacto presupuestario de los biomarcadores GFAP y UCH-L1 en el TCE leve en España https://www.infosalut.com/es/investigacio/estudis-i-projectes/17854 https://doi.org/10.3390/jcm14124095
#TBT Studying Parkinson's disease (PD) or other neurodegenerative diseases?
In 2023, a blog post highlighted how our fetal bovine serum (FBS) and antibodies were utilized to study PD.
Along with these products, we also have a selection of human cells for PD.
www.neuromics.com/neuromics-pr...
In 2023, a blog post highlighted how our fetal bovine serum (FBS) and antibodies were utilized to study PD.
Along with these products, we also have a selection of human cells for PD.
www.neuromics.com/neuromics-pr...
May 22, 2025 at 3:23 PM
#TBT Studying Parkinson's disease (PD) or other neurodegenerative diseases?
In 2023, a blog post highlighted how our fetal bovine serum (FBS) and antibodies were utilized to study PD.
Along with these products, we also have a selection of human cells for PD.
www.neuromics.com/neuromics-pr...
In 2023, a blog post highlighted how our fetal bovine serum (FBS) and antibodies were utilized to study PD.
Along with these products, we also have a selection of human cells for PD.
www.neuromics.com/neuromics-pr...
www.ncbi.nlm.nih.gov/pmc/articles...
"Autoimmune glial fibrillary acidic protein ( #GFAP) astrocytopathy is a novel autoimmune disease of central nervous system (CNS)."
"Autoimmune glial fibrillary acidic protein ( #GFAP) astrocytopathy is a novel autoimmune disease of central nervous system (CNS)."
Epstein–Barr virus: To be a trigger of autoimmune glial fibrillary acidic protein astrocytopathy?
Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a novel autoimmune disease of central nervous system (CNS). It is unclear whether Epstein–Barr virus (EBV) is related to autoimmune ...
www.ncbi.nlm.nih.gov
January 13, 2025 at 5:51 PM
www.ncbi.nlm.nih.gov/pmc/articles...
"Autoimmune glial fibrillary acidic protein ( #GFAP) astrocytopathy is a novel autoimmune disease of central nervous system (CNS)."
"Autoimmune glial fibrillary acidic protein ( #GFAP) astrocytopathy is a novel autoimmune disease of central nervous system (CNS)."
A @karolinskainst.bsky.social study shows plasma #biomarkers pTau181, 217, 231, and GFAP are associated with accumulation of mis-folded amyloid in the brain in #Alzheimers. pTau217 is a dual marker of amyloid and tau pathology.
#dementia #neuroscience #neuroskyence
#dementia #neuroscience #neuroskyence
Disentangling relationships between Alzheimer's disease plasma biomarkers and established biomarkers in patients of tertiary memory clinics
Amyloid burden primarily drives the changes in plasma pTau181, pTau217, pTau231, and GFAP. In contrast to plasma pTau217, a significant portion of variance in plasma pTau181, pTau231, GFAP, NfL remains unexplained by clinical AD biomarkers.
www.thelancet.com
December 21, 2024 at 12:31 PM
A @karolinskainst.bsky.social study shows plasma #biomarkers pTau181, 217, 231, and GFAP are associated with accumulation of mis-folded amyloid in the brain in #Alzheimers. pTau217 is a dual marker of amyloid and tau pathology.
#dementia #neuroscience #neuroskyence
#dementia #neuroscience #neuroskyence
Plasma Glial Fibrillary Acidic Protein (GFAP) as a Biomarker of Acute Focal Brain Injury https://www.medrxiv.org/content/10.1101/2024.10.11.24315320v1
Plasma Glial Fibrillary Acidic Protein (GFAP) as a Biomarker of Acute Focal Brain Injury https://www.medrxiv.org/content/10.1101/2024.10.11.24315320v1
Objective: The validation of acute brain injury biomarkers has encountered challenges such as the ab
www.medrxiv.org
October 16, 2024 at 1:27 PM
Plasma Glial Fibrillary Acidic Protein (GFAP) as a Biomarker of Acute Focal Brain Injury https://www.medrxiv.org/content/10.1101/2024.10.11.24315320v1
I will have to look when back in the lab but I want to say 90% chance this is GFAP just because of the thick intermediate filament looking strands
November 27, 2024 at 12:35 AM
I will have to look when back in the lab but I want to say 90% chance this is GFAP just because of the thick intermediate filament looking strands
Astrocyte in culture
Green: Glial fibrillary acidic protein (GFAP) filaments, immunofluorescence
Blue: Nucleus, Hoechst
#FluorescenceFriday
Green: Glial fibrillary acidic protein (GFAP) filaments, immunofluorescence
Blue: Nucleus, Hoechst
#FluorescenceFriday
December 20, 2024 at 2:48 PM
Astrocyte in culture
Green: Glial fibrillary acidic protein (GFAP) filaments, immunofluorescence
Blue: Nucleus, Hoechst
#FluorescenceFriday
Green: Glial fibrillary acidic protein (GFAP) filaments, immunofluorescence
Blue: Nucleus, Hoechst
#FluorescenceFriday
zum Gehirn verschaffen, was bei der Influenza nicht möglich ist.
A: Virusinfektion peripherer Nerven (z. B. Riechkolben)
B: Schädigung infizierter Endothelzellen
C: Kaperung von Immunzellen
D: Virale Öffnung von Tight Junctions
Einige Studien zeigen, dass einige Grippestämme den
A: Virusinfektion peripherer Nerven (z. B. Riechkolben)
B: Schädigung infizierter Endothelzellen
C: Kaperung von Immunzellen
D: Virale Öffnung von Tight Junctions
Einige Studien zeigen, dass einige Grippestämme den
March 16, 2024 at 11:41 PM
zum Gehirn verschaffen, was bei der Influenza nicht möglich ist.
A: Virusinfektion peripherer Nerven (z. B. Riechkolben)
B: Schädigung infizierter Endothelzellen
C: Kaperung von Immunzellen
D: Virale Öffnung von Tight Junctions
Einige Studien zeigen, dass einige Grippestämme den
A: Virusinfektion peripherer Nerven (z. B. Riechkolben)
B: Schädigung infizierter Endothelzellen
C: Kaperung von Immunzellen
D: Virale Öffnung von Tight Junctions
Einige Studien zeigen, dass einige Grippestämme den
2-for-1 post coming at you for both #worldparkinsonsday and #fluorescencefriday
Another #astrocyte grown on coverglass reminding everyone of the important role of #glia in #parkinsons
🧪🔬
Another #astrocyte grown on coverglass reminding everyone of the important role of #glia in #parkinsons
🧪🔬
April 11, 2025 at 5:04 PM
2-for-1 post coming at you for both #worldparkinsonsday and #fluorescencefriday
Another #astrocyte grown on coverglass reminding everyone of the important role of #glia in #parkinsons
🧪🔬
Another #astrocyte grown on coverglass reminding everyone of the important role of #glia in #parkinsons
🧪🔬
2️⃣ Shorena Janelidze and Lyduine Collij investigated in 258 adults with DS, the association of baseline and longitudinal assessments of plasma p-tau217, GFAP, Aβ42/40, NfL, and total tau (t-tau) with changes in global cognitive functioning (DS-MSE), Aβ-PET, and tau-PET.
June 27, 2025 at 11:54 AM
2️⃣ Shorena Janelidze and Lyduine Collij investigated in 258 adults with DS, the association of baseline and longitudinal assessments of plasma p-tau217, GFAP, Aβ42/40, NfL, and total tau (t-tau) with changes in global cognitive functioning (DS-MSE), Aβ-PET, and tau-PET.
GFAP Proteolysis in TBI: Linking Novel Modified Cleavage Products to Astrocyte Pathology and Patient Outcomes https://www.biorxiv.org/content/10.1101/2025.08.01.668181v1
August 1, 2025 at 10:15 PM
GFAP Proteolysis in TBI: Linking Novel Modified Cleavage Products to Astrocyte Pathology and Patient Outcomes https://www.biorxiv.org/content/10.1101/2025.08.01.668181v1