La NMPA de China aprueba la comercialización de Entinostat Tablets

📩 info@dengyuemed.com
🔗https://dengyuepharma.com

#Entinostat #EntinostatTablets #Jingzhuda
#CáncerDeMama #CáncerDeMamaMetastásico
#HRpositivo #HER2negativo
#InhibidorHDAC #TerapiaDirigida

Kaduk and Rai: Structure of entinostat Form B, C21H20N4O3, derived using laboratory powder diffraction data and density functional techniques ##PowderDiffraction##Entinostat##RietveldRefinement... ##IUCrhttps://journals.iucr.org/paper?S2056989025007406

- A viral imprint reflected in molecular signatures of EBV, HIV and HSV

Potential therapeutic strategies (at least in silico):

- HDAC inhibitors (e.g. Entinostat, Vorinostat) — particularly interesting due to their epigenetic mechanisms
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- Virusimprint durch molekulare Signaturen von EBV, HIV, HSV

Therapieansätze (zumindest in silico)
- HDAC-Hemmer (z.B. Entinostat, Vorinostat; interessant v. a. weil epigenetischer Ansatz)
- Östrogen-Antagonisten (Fulvestrant)
➡️ Evtl.
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At #ASCO25 this morning, Tracy Rose, MD, MPH, will present at the poster session: (Poster 403) Pathologic response and safety of neoadjuvant pembrolizumab with or without entinostat in muscle-invasive urothelial cancer (MIUC).

⌚️: 9 a.m. - 12 p.m. CT
📍: Hall A

PXD055268 🚨

A novel nontoxic combination of ERAP1 silencing and entinostat therapy to overcome resistance to cancer immunotherapy in neuroblastoma

🚨 New dataset alert! 🚨

A paper using RRID:Addgene_12259 was just published in Frontiers in Immunology see "Entinostat, a histone deacetylase inhibitor, enhances CAR-NK cell anti-tumor activity by sustaining CAR expression". RRIDs like this improve reproducibility in scientific research. #accelerateopenscience

Entinostat, a histone deacetylase inhibitor, enhances CAR-NK cell anti-tumor activity by sustaining CAR expression
doi.org/10.3389/fimm...

RRID:CVCL_0434 was used by the authors of the Neoplasia paper "Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat". RRIDs like this improve reproducibility in scientific research. #ReproducibleResearch #OpenScience