#DiscomfortOfThought
#DiscomfortOfThought required to #RethinkNicotine.

And there's plenty to be uncomfortable about.

But I do believe we all have to get more comfortable with being uncomfortable. I am grateful that @unbiasedscipod.bsky.social agrees on that point.

#respect
Nuance is hard. Reflexive positions are easy. Public health has a long, fraught history with Big Tobacco, and that history makes it difficult to look at anything the industry touches without suspicion. I get it. I feel it.
The Call I Didn’t Want to Take
I lost my dad to cigarettes. Then I took a call from the vape industry.
open.substack.com
January 31, 2026 at 4:56 PM
Wow! Nicotine pouch sales in US increased 2.8 times in 2 years! And you still think this strong demand for tobacco harm reduction can be stopped by legislation & enforcement? Harm reduction works & consumers love it even if politicians don’t! @chancethegardener.bsky.social @jgitchell.bsky.social
June 19, 2025 at 1:22 AM
#DiscomfortOfThought, Antipodean style.

Go go go, @alexwodak.bsky.social

Who's ready to get less wrong, together?
1/4 Cochrane review concludes ‘For every 100 people using nicotine e‐cigarettes to stop #smoking, 8 to 10 might successfully stop, compared with only 6 of 100 people using nicotine‐replacement therapy’. Some say insignificant difference. But still a ~60% improvement vs gold standard NRT!
June 5, 2025 at 8:19 PM
From almost 3 years ago but still bigly relevant.

#DiscomfortOfThought required to #RethinkNicotine.
Ethan Nadelmann interviews André Calantzoulos, Chair of Board of PMI, world’s 2nd largest tobacco company: what is PMI’s attitude to tobacco harm reduction and why? Highly recommended @chancethegardener.bsky.social @jgitchell.bsky.social @ianamossyd.bsky.social
open.spotify.com/episode/5SPE...
André Calantzopoulos on Profiting from Nicotine
PSYCHOACTIVE · Episode
open.spotify.com
May 10, 2025 at 10:37 PM
#DiscomfortOfThought required to #RethinkNicotine.

Props to Adam Cifu of Sensible Medicine for sharing Brad Rodu's post, along with context about Dr Cifu's priors about the oral cancer risks from smokeless tobacco.

Link follows.

#TobRegSky

1/2
May 3, 2025 at 10:37 AM
#DiscomfortOfThought coming in white 🔥🔥🔥.

#TobRegSky
What is NOT my goal for nicotine policy? To eradicate or seriously damage tobacco companies. Why? Because strong demand will always create strong supply. Better to have Big Tobacco switch to profitably making low risk products @chancethegardener.bsky.social
@jgitchell.bsky.social
April 29, 2025 at 3:19 PM
PMI world’s largest traded tobacco co just released 1Q25 results:
‘Our smoke-free business, accounting for 42% of our total net revenues & 44% of our total gross profit, continued its strong momentum with increases of 14.4% in shipment volumes’
@jgitchell.bsky.social
@aliveadvocacy.bsky.social
April 23, 2025 at 10:29 PM
#DiscomfortOfThought comes for us all.
Smoke free products accounted for 0.2% of revenue for Philip Morris International, world’s largest traded tobacco company, in 2015. 9 years later in 2024, they accounted for 40% of revenue! Powerful market forces will be the undoing of tobacco harm reduction denialism @jgitchell.bsky.social
March 17, 2025 at 12:41 AM
For #DiscomfortOfThought consider these words once spoken @elilillyandcompany.bsky.social:
“No one would ever take an injection to treat a disease as benign as obesity.”

Today's reminder to check our opinions in case they are colored by #bias.
conscienhealth.org/2025/03/the-...
March 14, 2025 at 10:09 AM
#DiscomfortOfThought vs #Righteousness

Sadly, not really the battle royale we might hope for! But we have to try!
My timeline is awash with “inspiring women” for international women’s day

This would be a great campaign IFF the bottleneck to equality was women’s stereotypes

Activists would be more effective if they actually used evidence on what works, without triggering backlash

🧵
March 8, 2025 at 11:34 AM
#DiscomfortOfThought required to #RethinkNicotine.

#TobRegSky

1/4

Six Urban Myths About Smoke-Free Nicotine www.sensible-med.com/p/six-urban-...
Six Urban Myths About Smoke-Free Nicotine
A scientific look at the myths surrounding nicotine.
www.sensible-med.com
March 4, 2025 at 11:20 AM
#DiscomfortOfThought spares no one.

@alexwodak.bsky.social

Why has New Zealand passed Australia in the smoking reduction derby?

t.co/UiMXgeItdp
https://colinmendelsohn.com.au/wp-content/uploads/2025/02/Mendelsohn-C.-Our-vaping-delusions-have-gone-up-in-smoke.-The-Kiwis-have-a-better-idea-SMH-2March2025.pdf
t.co
March 1, 2025 at 8:13 PM
Roses are red,
Violets are blue.
Imagine if all people who smoke
Knew what I do.

#DiscomfortOfThought required to #RethinkNicotine.

#StayCurious

#HealthValentines
a man with a mustache is pointing at someone with the words let me hit you with some knowledge below him
Alt: Dodgeball's White Goodman (Ben Stiller) "Let me hit you with some knowledge."
media.tenor.com
February 14, 2025 at 12:14 PM
Bigly #DiscomfortOfThought as @alicedreger.bsky.social interviews @retractionwatch.com's Ivan Oransky.

FYI @jeremyfaust.bsky.social

“Demoralizing and Paralyzing Scientists Pursuing the Truth”: Q&A with Ivan Oransky open.substack.com/pub/heterodo...
“Demoralizing and Paralyzing Scientists Pursuing the Truth”: Q&A with Ivan Oransky
Strictures now put on CDC scientists’ language have consequences for academic research and public health.
open.substack.com
February 10, 2025 at 6:24 PM
#TobRegSky

Folks who appreciate the tickle of the #DiscomfortOfThought might appreciate @whyy.org 's Nicole Leonard's reporting on Zyn authorizations.

@ru-ints.bsky.social @maryhrywna.bsky.social

whyy.org/articles/fda...
FDA regulation of nicotine pouches can prevent youth use, say Rutgers experts
Nicotine pouches are a newer class of smokeless products that don’t contain tobacco. Zyn became the first FDA-authorized brand on Jan. 16.
whyy.org
January 19, 2025 at 12:52 PM
Big #DiscomfortOfThought Energy from Marc Gunther writing in Filter.

Includes input from @CliveBates.bsky.social & @ArielleSelya.bsky.social!

#StayCurious
#TobRegSky

How the FDA Made a “Gigantic, Chaotic Mess” of the US Vapes Market

filtermag.org/fda-vapes-ma...
How the FDA Made a “Gigantic, Chaotic Mess” of the US Vapes Market
Twenty-one years ago, a Chinese pharmacist named Hon Lik patented the first electronic cigarette. Lik smoked heavily, and hoped to ...
filtermag.org
January 9, 2025 at 5:12 PM
Here is my 2nd of two pieces about New Year's.
skipscorner.substack.com/p/the-ghost-...
The Ghost of New Year's Past acknowledges the depression I struggle with. It also compares what I've heard about people vs. what I learned.
#DiscomfortOfThought #THR #Smoking #Vaping
The Ghost of New Year's Past
There's a conflict between what I've heard and what I've learned.
skipscorner.substack.com
January 1, 2025 at 9:10 PM
Lo, if we could embrace #DiscomfortOfThought, pick up what Cory Clark is putting down in this short Heterodox Academy clip, and become less wrong, together!

#OptimismBias

#TobRegSky

youtu.be/p1YE55J4PHc?...
Adversaries to Allies: Transforming Academic Conflict - Cory Clark
YouTube video by Heterodox Academy
youtu.be
December 13, 2024 at 3:06 PM
Helpful #DiscomfortOfThought from @landmanspeaking.bsky.social. Includes lots of @jayvanbavel.bsky.social input!

I can think of a topic that is very ready for the reco'd treatment in the screenshot, below!
November 27, 2024 at 1:58 PM
This focuses on nicotine policy stuff, but big #DiscomfortOfThought and #ProphetsVsWizards energy.

tobaccoreporter.com/2024/06/01/r...
Realists and Idealists
Why we should celebrate ‘realists’ and beware of ‘idealists.’
tobaccoreporter.com
June 1, 2024 at 9:32 PM
If you think that a second Trump presidency would be a disaster for the US (I do) and that the election could come down to super tight margins in swing states (sadly plausible), then I think you should be wary of pressuring Biden to ban a product used by millions of people.
slate.com/technology/2...
If Biden Bans Menthol Cigarettes, Could He Hand the Election to Trump? It’s a Valid Concern.
Millions of people smoke them. Just a few votes could really matter.
slate.com
April 11, 2024 at 6:36 PM
So Chef Grier serves up an ample portion of #DiscomfortOfThought in this piece for Slate.

I'd love reactions from chums who may see it differently (eg @micahberman.bsky.social @sejordt.bsky.social).

#TobRegSky
Today in Slate, I wrote about the political risks of announcing a menthol ban in an election year and encourage activists to cut Biden some slack. It's a potentially divisive issue now and he'll have plenty of leeway in 2025, but first he has to win. slate.com/technology/2...
If Biden Bans Menthol Cigarettes, Could He Hand the Election to Trump? It’s a Valid Concern.
Millions of people smoke them. Just a few votes could really matter.
slate.com
April 8, 2024 at 5:30 PM