#Bedmed-Frail
Bedtime vs Morning Antihypertensive Medications in Frail Older Adults: The BedMed-Frail Randomized Clinical Trial.

JAMA Netw Open 2025
2/6
November 24, 2025 at 3:07 AM
OMAN is interesting. They enrolled a nocturnal htn population. Something that TIME, BedMed, BedMed-Frail were not able to do.
October 30, 2025 at 3:48 PM
Afraid not - wrote a short blog about it www.nephjc.com/news/bedmed (main BEDMED - this is BEDMED frail with similar results)
NephJC Shorts: BedMed and Chronotherapy — NephJC
The NephJC shorts version of the BedMed trial from JAMA
www.nephjc.com
July 19, 2025 at 10:56 AM
Morning vs Nighttime Hypertension Medication Dosing url:https://jamanetwork.com/journals/jama/fullarticle/2834002 #Bedmed-Frail trial -At the end of the day, timing of medications doesn’t matter as much as consistency in taking them.
June 18, 2025 at 2:42 AM
"Bedtime vs Morning Antihypertensive Medications in Frail Older Adults
The BedMed-Frail Randomized Clinical Trial."
Publié en mai dans @jamanetworkopen.com.
#MedSky
jamanetwork.com/journals/jam...
Bedtime vs Morning Antihypertensive Medications in Frail Older Adults
This randomized clinical trial compares bedtime vs morning administration of antihypertensive medications and its effect on major cardiovascular events and death among older frail adults.
jamanetwork.com
June 6, 2025 at 12:21 PM
【施設高齢者でも就寝前降圧薬服用の有用性認めず?:RCT
 “BedMed-Frail”/ JAMA NwO】

カナダ、継続ケア施設在住の1日1回型降圧薬服用776例 [中央値88歳] ランダム化、415日 [中央値] 観察:

・41%が「死亡・CV疾患入院/救急受診」。
・降圧薬「就寝前」服用で「起床後」に比べ、補正後HRは0.88
 [95%CI:%CI:0.71-1.11]で有意差なし。
・ただし有意な性差あり [男性では就寝前服用でリスク低下。交
 互作用p=0.03] 。

x.gd/LvNvK
#降圧薬 #就寝前
May 12, 2025 at 10:27 PM
Accompanied by BEDMED Frail in JNO

jamanetwork.com/journals/jam...

2/
May 12, 2025 at 9:46 PM
Antihypertensiva morgens oder wegen nächtlicher Hypertonie besser abends? TIME-, BedMed- und BedMed-Frail-Studie: weder Vor- noch Nachteile bzgl. kardiovaskulärer Ereignisse. Ergo: Patienten selbst in indiv. Rhythmus einpflegen lassen. Hinweise geben (Diuretika morgens, usw.)
February 21, 2025 at 8:25 AM