Andrea Zingaro
@zingaro7.bsky.social
Ph.D. student at @irbbarcelona.org in Raul Mendez lab | #MSCActions fellow | Passionate about #RNAbiology and #TranslationControl mechanisms in disease and physiological conditions.
Pinned
Andrea Zingaro
@zingaro7.bsky.social
· Feb 13
Remodelling of the translatome controls diet and its impact on tumorigenesis - Nature
During fasting, hepatocytes selectively remodel the translatome while global translation is downregulated, showing a new signalling property of fatty acids and that, on a ketogenic diet, treatment wit...
www.nature.com
Excited to share that our research has been published in @nature.com
! We discovered a novel FA-induced pathway that drives selective translation via eIF4E phosphorylation, key to ketogenesis and potential cancer therapy. Read more here:
! We discovered a novel FA-induced pathway that drives selective translation via eIF4E phosphorylation, key to ketogenesis and potential cancer therapy. Read more here:
Last week we brought #IRBPhDDay2025 to life at @irbbarcelona.org.
Together with other 7 brilliant fellow PhD students, we organized a full day of science, connection & community.
Proud of what we built. By PhD students, for PhD students.
Thank you to all who made it possible!
Together with other 7 brilliant fellow PhD students, we organized a full day of science, connection & community.
Proud of what we built. By PhD students, for PhD students.
Thank you to all who made it possible!
The 2nd #IRBBarcelona #PhD Day has been a great success. A huge thank you to all participants & speakers! Special congrats to our best speakers:
𝗚𝗶𝗮𝗰𝗼𝗺𝗼 𝗠𝘂𝘁𝘁𝗶-Long Talk
𝗩𝗮𝗹𝗲𝗻𝘁𝗶𝗻 𝗣𝗹𝗲𝘁𝗲𝗮 & 𝗟𝘂𝗶𝘀 𝗡𝗶𝗲𝘁𝗼 𝗕𝗮𝗿𝗿𝗮𝗱𝗼-Flash Talks
𝗞𝗮𝘂𝘀𝘁𝘂𝘃 𝗚𝗵𝗼𝘀𝗵 & 𝗠𝗮𝗿𝘁𝗶́ 𝗦𝗶𝗱𝗿𝗼 𝗜𝗻𝗴𝗹𝗲́𝘀-Short Talks
𝗚𝗶𝘂𝗹𝗶𝗮 𝗩𝗶𝗼𝗹𝗮-Poster Session
𝗚𝗶𝗮𝗰𝗼𝗺𝗼 𝗠𝘂𝘁𝘁𝗶-Long Talk
𝗩𝗮𝗹𝗲𝗻𝘁𝗶𝗻 𝗣𝗹𝗲𝘁𝗲𝗮 & 𝗟𝘂𝗶𝘀 𝗡𝗶𝗲𝘁𝗼 𝗕𝗮𝗿𝗿𝗮𝗱𝗼-Flash Talks
𝗞𝗮𝘂𝘀𝘁𝘂𝘃 𝗚𝗵𝗼𝘀𝗵 & 𝗠𝗮𝗿𝘁𝗶́ 𝗦𝗶𝗱𝗿𝗼 𝗜𝗻𝗴𝗹𝗲́𝘀-Short Talks
𝗚𝗶𝘂𝗹𝗶𝗮 𝗩𝗶𝗼𝗹𝗮-Poster Session
October 23, 2025 at 7:21 PM
Last week we brought #IRBPhDDay2025 to life at @irbbarcelona.org.
Together with other 7 brilliant fellow PhD students, we organized a full day of science, connection & community.
Proud of what we built. By PhD students, for PhD students.
Thank you to all who made it possible!
Together with other 7 brilliant fellow PhD students, we organized a full day of science, connection & community.
Proud of what we built. By PhD students, for PhD students.
Thank you to all who made it possible!
Reposted by Andrea Zingaro
The 2nd #IRBBarcelona #PhD Day has been a great success. A huge thank you to all participants & speakers! Special congrats to our best speakers:
𝗚𝗶𝗮𝗰𝗼𝗺𝗼 𝗠𝘂𝘁𝘁𝗶-Long Talk
𝗩𝗮𝗹𝗲𝗻𝘁𝗶𝗻 𝗣𝗹𝗲𝘁𝗲𝗮 & 𝗟𝘂𝗶𝘀 𝗡𝗶𝗲𝘁𝗼 𝗕𝗮𝗿𝗿𝗮𝗱𝗼-Flash Talks
𝗞𝗮𝘂𝘀𝘁𝘂𝘃 𝗚𝗵𝗼𝘀𝗵 & 𝗠𝗮𝗿𝘁𝗶́ 𝗦𝗶𝗱𝗿𝗼 𝗜𝗻𝗴𝗹𝗲́𝘀-Short Talks
𝗚𝗶𝘂𝗹𝗶𝗮 𝗩𝗶𝗼𝗹𝗮-Poster Session
𝗚𝗶𝗮𝗰𝗼𝗺𝗼 𝗠𝘂𝘁𝘁𝗶-Long Talk
𝗩𝗮𝗹𝗲𝗻𝘁𝗶𝗻 𝗣𝗹𝗲𝘁𝗲𝗮 & 𝗟𝘂𝗶𝘀 𝗡𝗶𝗲𝘁𝗼 𝗕𝗮𝗿𝗿𝗮𝗱𝗼-Flash Talks
𝗞𝗮𝘂𝘀𝘁𝘂𝘃 𝗚𝗵𝗼𝘀𝗵 & 𝗠𝗮𝗿𝘁𝗶́ 𝗦𝗶𝗱𝗿𝗼 𝗜𝗻𝗴𝗹𝗲́𝘀-Short Talks
𝗚𝗶𝘂𝗹𝗶𝗮 𝗩𝗶𝗼𝗹𝗮-Poster Session
October 23, 2025 at 7:02 AM
The 2nd #IRBBarcelona #PhD Day has been a great success. A huge thank you to all participants & speakers! Special congrats to our best speakers:
𝗚𝗶𝗮𝗰𝗼𝗺𝗼 𝗠𝘂𝘁𝘁𝗶-Long Talk
𝗩𝗮𝗹𝗲𝗻𝘁𝗶𝗻 𝗣𝗹𝗲𝘁𝗲𝗮 & 𝗟𝘂𝗶𝘀 𝗡𝗶𝗲𝘁𝗼 𝗕𝗮𝗿𝗿𝗮𝗱𝗼-Flash Talks
𝗞𝗮𝘂𝘀𝘁𝘂𝘃 𝗚𝗵𝗼𝘀𝗵 & 𝗠𝗮𝗿𝘁𝗶́ 𝗦𝗶𝗱𝗿𝗼 𝗜𝗻𝗴𝗹𝗲́𝘀-Short Talks
𝗚𝗶𝘂𝗹𝗶𝗮 𝗩𝗶𝗼𝗹𝗮-Poster Session
𝗚𝗶𝗮𝗰𝗼𝗺𝗼 𝗠𝘂𝘁𝘁𝗶-Long Talk
𝗩𝗮𝗹𝗲𝗻𝘁𝗶𝗻 𝗣𝗹𝗲𝘁𝗲𝗮 & 𝗟𝘂𝗶𝘀 𝗡𝗶𝗲𝘁𝗼 𝗕𝗮𝗿𝗿𝗮𝗱𝗼-Flash Talks
𝗞𝗮𝘂𝘀𝘁𝘂𝘃 𝗚𝗵𝗼𝘀𝗵 & 𝗠𝗮𝗿𝘁𝗶́ 𝗦𝗶𝗱𝗿𝗼 𝗜𝗻𝗴𝗹𝗲́𝘀-Short Talks
𝗚𝗶𝘂𝗹𝗶𝗮 𝗩𝗶𝗼𝗹𝗮-Poster Session
Reposted by Andrea Zingaro
🤗Here are some highlights from this #OpenDayIRB25 morning with families!
🔎Discoveries, experiences, and smiles from the little ones during the science workshops, the escape room, and the lab
tours.
We also danced a lot during the #RadioPAati concert by Amanda Álvaro and @thecrabapple.bsky.social 🎶
🔎Discoveries, experiences, and smiles from the little ones during the science workshops, the escape room, and the lab
tours.
We also danced a lot during the #RadioPAati concert by Amanda Álvaro and @thecrabapple.bsky.social 🎶
May 24, 2025 at 12:49 PM
🤗Here are some highlights from this #OpenDayIRB25 morning with families!
🔎Discoveries, experiences, and smiles from the little ones during the science workshops, the escape room, and the lab
tours.
We also danced a lot during the #RadioPAati concert by Amanda Álvaro and @thecrabapple.bsky.social 🎶
🔎Discoveries, experiences, and smiles from the little ones during the science workshops, the escape room, and the lab
tours.
We also danced a lot during the #RadioPAati concert by Amanda Álvaro and @thecrabapple.bsky.social 🎶
Reposted by Andrea Zingaro
✨ Get ready to be inspired at the #IRBBarcelona #OpenDay!
🎯 Save the date!
🗓️ Saturday, May 24
Morning = family fun 👨👩👧👦
Afternoon = deep science dive 🔍
Sign up here! 🔗 bit.ly/3Z1wf6b
#ScienceForEveryone
🧪
🎯 Save the date!
🗓️ Saturday, May 24
Morning = family fun 👨👩👧👦
Afternoon = deep science dive 🔍
Sign up here! 🔗 bit.ly/3Z1wf6b
#ScienceForEveryone
🧪
May 2, 2025 at 9:21 AM
✨ Get ready to be inspired at the #IRBBarcelona #OpenDay!
🎯 Save the date!
🗓️ Saturday, May 24
Morning = family fun 👨👩👧👦
Afternoon = deep science dive 🔍
Sign up here! 🔗 bit.ly/3Z1wf6b
#ScienceForEveryone
🧪
🎯 Save the date!
🗓️ Saturday, May 24
Morning = family fun 👨👩👧👦
Afternoon = deep science dive 🔍
Sign up here! 🔗 bit.ly/3Z1wf6b
#ScienceForEveryone
🧪
Reposted by Andrea Zingaro
"Investment in Barcelona’s biotech sector is also booming, with international investors increasingly seeing the city as a potential hotbed for therapeutic breakthroughs"
Why biotech is booming in Barcelona
World-class research institutes and university hospitals, a culture of groundbreaking science and a thriving investment ecosystem make Barcelona a rising star in the life sciences industry, as these t...
www.nature.com
April 22, 2025 at 7:25 AM
"Investment in Barcelona’s biotech sector is also booming, with international investors increasingly seeing the city as a potential hotbed for therapeutic breakthroughs"
Reposted by Andrea Zingaro
Online Now: Kuzuoglu-Ozturk et al. showcase a therapeutic approach, “translatome therapy,” to combat lethal prostate cancer. Zotatifin, a clinical molecule, targets the RNA-helicase eIF4A. Zotatifin decreases the select translation of key oncogenes, androgen receptor (AR), and HIF1α through…
Small-molecule RNA therapeutics to target prostate cancer
Kuzuoglu-Ozturk et al. showcase a therapeutic approach, “translatome therapy,” to combat lethal prostate cancer. Zotatifin, a clinical molecule, targets the RNA-helicase eIF4A. Zotatifin decreases the select translation of key oncogenes, androgen receptor (AR), and HIF1α through remodeling their 5′ UTR RNA structure. Zotatifin enhances anti-androgen and radiotherapy sensitivity, highlighting a promising anti-cancer treatment.
dlvr.it
March 21, 2025 at 2:17 PM
Online Now: Kuzuoglu-Ozturk et al. showcase a therapeutic approach, “translatome therapy,” to combat lethal prostate cancer. Zotatifin, a clinical molecule, targets the RNA-helicase eIF4A. Zotatifin decreases the select translation of key oncogenes, androgen receptor (AR), and HIF1α through…
Reposted by Andrea Zingaro
🟣 On #WomensDay, we recognize the incredible women of #IRBBarcelona! Researchers, technicians, managers, and other professionals whose talent and dedication push the boundaries of knowledge.
Your work fuels discovery and paves the way for future generations of women in science.
Thank you! 🙌
#8M
Your work fuels discovery and paves the way for future generations of women in science.
Thank you! 🙌
#8M
March 8, 2025 at 9:02 AM
🟣 On #WomensDay, we recognize the incredible women of #IRBBarcelona! Researchers, technicians, managers, and other professionals whose talent and dedication push the boundaries of knowledge.
Your work fuels discovery and paves the way for future generations of women in science.
Thank you! 🙌
#8M
Your work fuels discovery and paves the way for future generations of women in science.
Thank you! 🙌
#8M
Excited to share that our research has been published in @nature.com
! We discovered a novel FA-induced pathway that drives selective translation via eIF4E phosphorylation, key to ketogenesis and potential cancer therapy. Read more here:
! We discovered a novel FA-induced pathway that drives selective translation via eIF4E phosphorylation, key to ketogenesis and potential cancer therapy. Read more here:
Remodelling of the translatome controls diet and its impact on tumorigenesis - Nature
During fasting, hepatocytes selectively remodel the translatome while global translation is downregulated, showing a new signalling property of fatty acids and that, on a ketogenic diet, treatment wit...
www.nature.com
February 13, 2025 at 6:43 PM
Excited to share that our research has been published in @nature.com
! We discovered a novel FA-induced pathway that drives selective translation via eIF4E phosphorylation, key to ketogenesis and potential cancer therapy. Read more here:
! We discovered a novel FA-induced pathway that drives selective translation via eIF4E phosphorylation, key to ketogenesis and potential cancer therapy. Read more here:
Reposted by Andrea Zingaro
🫧🔍Key breakthrough in #autism: pivotal role of #CPEB4 condensates revealed.
💊The study opens new avenues for the development of targeted treatments for autism.
📰 Nature @natureportfolio.bsky.social
✍️ Carla Garcia-Cabau, Anna Bartomeu et al.
➡️ bit.ly/3BfEGlR
📌 DOI: 10.1038/s41586-024-08289-w
💊The study opens new avenues for the development of targeted treatments for autism.
📰 Nature @natureportfolio.bsky.social
✍️ Carla Garcia-Cabau, Anna Bartomeu et al.
➡️ bit.ly/3BfEGlR
📌 DOI: 10.1038/s41586-024-08289-w
December 4, 2024 at 4:00 PM
🫧🔍Key breakthrough in #autism: pivotal role of #CPEB4 condensates revealed.
💊The study opens new avenues for the development of targeted treatments for autism.
📰 Nature @natureportfolio.bsky.social
✍️ Carla Garcia-Cabau, Anna Bartomeu et al.
➡️ bit.ly/3BfEGlR
📌 DOI: 10.1038/s41586-024-08289-w
💊The study opens new avenues for the development of targeted treatments for autism.
📰 Nature @natureportfolio.bsky.social
✍️ Carla Garcia-Cabau, Anna Bartomeu et al.
➡️ bit.ly/3BfEGlR
📌 DOI: 10.1038/s41586-024-08289-w