Zhenzhen Wu
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zhenzhenwu.bsky.social
Zhenzhen Wu
@zhenzhenwu.bsky.social
Our new preprint is now on BioRxiv! Very excited to share this this work. Come take a look at what we have been working on! 😊
December 9, 2025 at 1:10 PM
Reposted by Zhenzhen Wu
New preprint out!
Our latest work on how ZAKα is activated by stalled or/and collided ribosomes is now online🎉. #Ribosome #RibotoxicStressResponse #ZAKα #Translation #mRNA www.biorxiv.org/content/10.1...
ZAKα is a sensor of mRNA stasis at the ribosomal exit channel
Despite a growing interest in the ribotoxic stress response (RSR), it remains unknown how the upstream p38 and JNK-activating MAP3 kinase ZAKα senses translational impairment. Combining Alphafold3 pre...
www.biorxiv.org
December 3, 2025 at 2:24 PM