Victor Zegarra
@zegarrv.bsky.social
PhD in Chemistry, Marburg University
Alum of Gert Bange 🇩🇪 and Pohl Milón 🇵🇪
Passionate about ribosomes & translational control, exploring neuronal regulation and neurodegeneration.
Alum of Gert Bange 🇩🇪 and Pohl Milón 🇵🇪
Passionate about ribosomes & translational control, exploring neuronal regulation and neurodegeneration.
Reposted by Victor Zegarra
Great to see our Science Review on emerging multiplexed single-molecule methods that use libraries to link sequence to dynamics. A fun collaborative writing project! From sequence to function: Bridging single-molecule kinetics and molecular diversity | Science www.science.org/doi/10.1126/...
From sequence to function: Bridging single-molecule kinetics and molecular diversity
Biological function is fundamentally determined by nucleic acid and protein sequence. Beyond encoding genetic information, nucleic acids also display complex physicochemical parameters that shape stru...
www.science.org
January 30, 2026 at 6:59 PM
Great to see our Science Review on emerging multiplexed single-molecule methods that use libraries to link sequence to dynamics. A fun collaborative writing project! From sequence to function: Bridging single-molecule kinetics and molecular diversity | Science www.science.org/doi/10.1126/...
Reposted by Victor Zegarra
Our new pre-print from the Greenberg and Churchman labs shows that activity-dependent modulation of RNA stability is a major, and underappreciated, mechanism of gene regulation in neurons. Tutorial below! www.biorxiv.org/content/10.1... (1/11)
HuD controls widespread RNA stability to drive neuronal activity-dependent responses
Neuronal activity shapes brain development and refines synaptic connectivity in part through dynamic changes in gene expression. While activity-regulated transcriptional programs have been extensively...
www.biorxiv.org
September 9, 2025 at 2:41 PM
Our new pre-print from the Greenberg and Churchman labs shows that activity-dependent modulation of RNA stability is a major, and underappreciated, mechanism of gene regulation in neurons. Tutorial below! www.biorxiv.org/content/10.1... (1/11)
Reposted by Victor Zegarra
Vesicular Rps6 released by astrocytes regulate local translation and enhance synaptic markers in neurons https://www.biorxiv.org/content/10.1101/2025.05.28.656644v1
May 29, 2025 at 6:16 AM
Vesicular Rps6 released by astrocytes regulate local translation and enhance synaptic markers in neurons https://www.biorxiv.org/content/10.1101/2025.05.28.656644v1
Reposted by Victor Zegarra
now online:
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...
Structures of naked mole-rat, tuco-tuco, and guinea pig ribosomes—is rRNA fragmentation linked to translational fidelity?
Abstract. Ribosomes are central to protein synthesis in all organisms. In mammals, the ribosome functional core is highly conserved. Remarkably, two rodent
academic.oup.com
January 29, 2026 at 1:47 PM
now online:
academic.oup.com/nar/article/...
academic.oup.com/nar/article/...