🧵3/3 And of course, none of this would have been possible without postdoc mentor Helene Benveniste, co-lead author Zohaib Khan🥇 @weillcornell.bsky.social and MANY others including the incredible, late, Allen Tannenbaum. Looking forward to more exciting brain-immune 🧠🦠🥼 research? Keep an eye out 👀😉

🧵2/3 Previous work shows CSF-lymph coupling can be affected by lifestyle 🚴🫀x genetics🧬 and *may* cause neurodegeneration with age/injury. An accompanying commentary from @laurenhablitz.bsky.social www.jci.org/articles/vie... highlight link between peripheral injury, brain health, and immune system.🦠

Exciting finding led by a group here at Yale. Just because you might not find a lot of T cells in the brain tissue typically doesn't mean they aren't highly influential! And this is one source of them

It may be tempting to see "AI" (as vague and nebulous as that term is) as an answer; a means to an end. Instead, consider it one of many tools in a collection of expertise that must be refined and combined with our knowledge, experience, and humanity toward the futures we want. Sensibly.

"If the only tool you have is a hammer, it is tempting to treat everything as if it were a nail." -Maslow, 1966

Congrats @siararouzer.bsky.social ! Keeping FASD research represented for the Gordis

4/10 Using experimental manipulations, we found that PV interneurons scale the inhibition they receive to maintain stability. When the activity of a PV interneuron increases, it “requests” more inhibitory inputs from other PV+ interneurons, effectively rebalancing its activity