Yuning Hong
@yuninghong.bsky.social
Professor in Chemistry | La Trobe Institute for Molecular Science | Building fluorescent molecules | Probing unfolded proteins in cells | https://scholars.latrobe.edu.au/yhong
Reposted by Yuning Hong
Have you ever thought of using a fluorescent probe to specifically enrich and profile proteins with disordered regions?
Read below about RUBICON (reactive unfolded protein-based identification of cysteine on enrichment), a new workflow which enables the identification of the disordered proteome!
Read below about RUBICON (reactive unfolded protein-based identification of cysteine on enrichment), a new workflow which enables the identification of the disordered proteome!
🎆 New #ToolsOfTheTrade 🎆
@shouxiang-zhang.bsky.social & owyongtc.bsky.social ( @yuninghong.bsky.social lab @latrobeuni.bsky.social )
profile disordered proteins using a chemical tag. Check out the workflow and potential applications below!
🔗 go.nature.com/414Qtfv
OG paper: go.nature.com/4i3AGok
@shouxiang-zhang.bsky.social & owyongtc.bsky.social ( @yuninghong.bsky.social lab @latrobeuni.bsky.social )
profile disordered proteins using a chemical tag. Check out the workflow and potential applications below!
🔗 go.nature.com/414Qtfv
OG paper: go.nature.com/4i3AGok
Profiling the disordered proteome in cells using a chemical tag - Nature Reviews Molecular Cell Biology
In this Tools of the Trade article, Zhang and Owyong (Hong lab) discuss the development of a fluorescent probe that binds disordered proteins in situ and allows their enrichment and identification usi...
go.nature.com
February 18, 2025 at 7:10 AM
Have you ever thought of using a fluorescent probe to specifically enrich and profile proteins with disordered regions?
Read below about RUBICON (reactive unfolded protein-based identification of cysteine on enrichment), a new workflow which enables the identification of the disordered proteome!
Read below about RUBICON (reactive unfolded protein-based identification of cysteine on enrichment), a new workflow which enables the identification of the disordered proteome!
Reposted by Yuning Hong
🎆 New #ToolsOfTheTrade 🎆
@shouxiang-zhang.bsky.social & owyongtc.bsky.social ( @yuninghong.bsky.social lab @latrobeuni.bsky.social )
profile disordered proteins using a chemical tag. Check out the workflow and potential applications below!
🔗 go.nature.com/414Qtfv
OG paper: go.nature.com/4i3AGok
@shouxiang-zhang.bsky.social & owyongtc.bsky.social ( @yuninghong.bsky.social lab @latrobeuni.bsky.social )
profile disordered proteins using a chemical tag. Check out the workflow and potential applications below!
🔗 go.nature.com/414Qtfv
OG paper: go.nature.com/4i3AGok
Profiling the disordered proteome in cells using a chemical tag - Nature Reviews Molecular Cell Biology
In this Tools of the Trade article, Zhang and Owyong (Hong lab) discuss the development of a fluorescent probe that binds disordered proteins in situ and allows their enrichment and identification usi...
go.nature.com
February 18, 2025 at 7:06 AM
🎆 New #ToolsOfTheTrade 🎆
@shouxiang-zhang.bsky.social & owyongtc.bsky.social ( @yuninghong.bsky.social lab @latrobeuni.bsky.social )
profile disordered proteins using a chemical tag. Check out the workflow and potential applications below!
🔗 go.nature.com/414Qtfv
OG paper: go.nature.com/4i3AGok
@shouxiang-zhang.bsky.social & owyongtc.bsky.social ( @yuninghong.bsky.social lab @latrobeuni.bsky.social )
profile disordered proteins using a chemical tag. Check out the workflow and potential applications below!
🔗 go.nature.com/414Qtfv
OG paper: go.nature.com/4i3AGok
Check out this piece by @shouxiang-zhang.bsky.social and @owyongtc.bsky.social on Nat Rev Mol Cell Biol! @latrobeuni.bsky.social
ICYMI: New Online! Profiling the disordered proteome in cells using a chemical tag
Profiling the disordered proteome in cells using a chemical tag
Nature Reviews Molecular Cell Biology, Published online: 13 February 2025; doi:10.1038/s41580-025-00833-4In this Tools of the Trade article, Zhang and Owyong (Hong lab) discuss the development of a fluorescent probe that binds disordered proteins in situ…
bit.ly
February 17, 2025 at 3:16 AM
Check out this piece by @shouxiang-zhang.bsky.social and @owyongtc.bsky.social on Nat Rev Mol Cell Biol! @latrobeuni.bsky.social
Reposted by Yuning Hong
New Online! Profiling the disordered proteome in cells using a chemical tag
Profiling the disordered proteome in cells using a chemical tag
Nature Reviews Molecular Cell Biology, Published online: 13 February 2025; doi:10.1038/s41580-025-00833-4In this Tools of the Trade article, Zhang and Owyong (Hong lab) discuss the development of a fluorescent probe that binds disordered proteins in situ…
bit.ly
February 13, 2025 at 11:59 PM
New Online! Profiling the disordered proteome in cells using a chemical tag
Reposted by Yuning Hong
Come join us for the Medicinal Chemistry & Chemical Biology Conference 2025 (MCCB 2025)
Darwin Australia 🐊
mccb2025.com.au
Darwin Australia 🐊
mccb2025.com.au
RACI Medicinal Chemistry & Chemical Biology Conference 2025 | Drug Discovery in the Territory
mccb2025.com.au
January 24, 2025 at 10:04 AM
Come join us for the Medicinal Chemistry & Chemical Biology Conference 2025 (MCCB 2025)
Darwin Australia 🐊
mccb2025.com.au
Darwin Australia 🐊
mccb2025.com.au
Reposted by Yuning Hong
Hi #TeamMassSpec! #FeMS+ has joined BlueSky! Please share and get the word out so we can build up a base here.
November 30, 2024 at 2:00 PM
Hi #TeamMassSpec! #FeMS+ has joined BlueSky! Please share and get the word out so we can build up a base here.
Very excited to share our work out at Nature Methods on a new method (RUBICON) based on a chemical probe to target in situ, enrich and profile endogenous disordered proteins in cells, including #IDPs and those that acquire disorder. #ozchem #proteostasis #TeamMassSpec #proteomics
rdcu.be/d1ru3
rdcu.be/d1ru3
Global analysis of endogenous protein disorder in cells
Nature Methods - This article reports a method based on a bifunctional chemical probe called TME and a workflow named RUBICON to capture, enrich and profile endogenous disordered proteins in cells....
rdcu.be
November 26, 2024 at 7:37 AM
Very excited to share our work out at Nature Methods on a new method (RUBICON) based on a chemical probe to target in situ, enrich and profile endogenous disordered proteins in cells, including #IDPs and those that acquire disorder. #ozchem #proteostasis #TeamMassSpec #proteomics
rdcu.be/d1ru3
rdcu.be/d1ru3