Folding-Function links?
Aligning individual HCP task functional activation maps & multi-modal parcellations (Glasser, M. F. et al) using MSM-HT, we find that better structural alignment did not improve functional overlap. 7/9

Neonates vs. Adults: What changes?
We observed consistency across both age groups, with neonatal samples showing less variation. However, rightward-asymmetric folding clusters had greater temporal lobe surface area than leftward - reversed in adults. 5/9

Greater asymmetry in the temporal lobe.
A higher proportion of temporal lobe clusters were leftward-asymmetric compared to other lobes. These motifs showed more anatomical heterogeneity than rightward ones, including interruptions and branching of the superior temporal sulcus. 4/9

Disentangling natural cortical shape variability from clinically relevant features starts with better characterizing its scale across large populations. Here, we introduce MSM-HT to parse cortical folding variability into a representative family of distinct anatomical motifs. 3/9

I'm very excited to share my PhD work "Motifs of brain cortical folding from birth to adulthood: structural asymmetry and folding-functional links". We identified and characterised the lobe-wise folding patterns using both 1110 young adults (HCP) and 781 term-age neonates (dHCP & BIBS studies). 1/9