Yojet
@yojet.bsky.social
Final year PhD candidate working to uncover the role of lipid 5-phosphatase in human brain development @NCBS, India.
Interested in neuroimmune interactions, physiology, and microglia.
Interested in neuroimmune interactions, physiology, and microglia.
One of the most rewarding aspects of this work is watching neurons and astrocytes come alive through calcium imaging!
Left: 90 day old iPS derived neurons showing spontaneous activity; right: astrocytes migrated out from brain orgs show robust Ca activity as well!
Left: 90 day old iPS derived neurons showing spontaneous activity; right: astrocytes migrated out from brain orgs show robust Ca activity as well!
November 11, 2025 at 6:53 PM
One of the most rewarding aspects of this work is watching neurons and astrocytes come alive through calcium imaging!
Left: 90 day old iPS derived neurons showing spontaneous activity; right: astrocytes migrated out from brain orgs show robust Ca activity as well!
Left: 90 day old iPS derived neurons showing spontaneous activity; right: astrocytes migrated out from brain orgs show robust Ca activity as well!
Reposted by Yojet
Research Briefing: Promoter editing generates stable setpoints of gene expression www.nature.com/articles/s41...
rdcu.be/eK2FW
rdcu.be/eK2FW
Promoter editing generates stable setpoints of gene expression - Nature Biotechnology
Precise control of transgene expression remains a challenge in engineering primary cells for diverse applications. We developed DIAL, a promoter editing framework that transmits transient inputs into ...
www.nature.com
October 15, 2025 at 12:57 PM
Research Briefing: Promoter editing generates stable setpoints of gene expression www.nature.com/articles/s41...
rdcu.be/eK2FW
rdcu.be/eK2FW
That’s so amazing! Looking forward, good luck!
June 13, 2025 at 4:47 AM
That’s so amazing! Looking forward, good luck!
Are there established protocols to generate entorhinal neurons from iPSCs in the dish?
June 12, 2025 at 6:14 PM
Are there established protocols to generate entorhinal neurons from iPSCs in the dish?
Thank you for the insight! Any marker you you suggest that can be used to definitively mark their presence? The induction is using small molecule approach.
April 27, 2025 at 4:57 AM
Thank you for the insight! Any marker you you suggest that can be used to definitively mark their presence? The induction is using small molecule approach.
Does TFAP2 work in your case for positively marking them? Also any idea on how *not* to get these in 2D neural inductions?
April 26, 2025 at 7:50 PM
Does TFAP2 work in your case for positively marking them? Also any idea on how *not* to get these in 2D neural inductions?
Congratulations to the team!
March 6, 2025 at 1:09 PM
Congratulations to the team!