Yizhou Dong lab
yizhoudonglab.bsky.social
Yizhou Dong lab
@yizhoudonglab.bsky.social
Donglab.net

Our research is devoted to drug discovery and delivery for the treatment of genetic disorders, infectious diseases and cancers.
Reposted by Yizhou Dong lab
In @natchembio.nature.com, @yizhoudonglab.bsky.social highlights GEMORNA, an AI framework that directly generates mRNA & circRNA sequences by jointly modeling CDSs & UTRs, for coordinated optimization of expression and stability.

An elegant tool to help design mRNAs!
www.nature.com/articles/s41...
AI-powered design accelerates the development of mRNA therapeutics - Nature Chemical Biology
mRNA has emerged as an important class of therapeutic molecules. Now, an artificial intelligence (AI)-driven framework, which can design mRNA sequences with enhanced stability and translational effici...
www.nature.com
November 14, 2025 at 8:41 PM
Reposted by Yizhou Dong lab
With co-authors Bram Teunissen & @yizhoudonglab.bsky.social, we dive into emerging ways to make LNPs more precise—from tuning their chemistry to reprogramming RNA expression and even controlling protein stability & localization >>> a road🗺️ for more intelligent delivery & broader applications ahead.
October 17, 2025 at 5:22 PM