Yehu Moran
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yehumoran.bsky.social
Yehu Moran
@yehumoran.bsky.social
Evolutionary and molecular biology seasoned with ecology
https://www.yehumoran.com/
Using mostly sea anemones and other cnidarians as my experimental model organisms. University Professor at HUJI and academic editor for EMBO Press. Opinions are my own.
5/5 kudos to Ton Sharoni, the PhD student who bravely led this long and challenging project, and to all the other researchers in my lab who participated and helped along the years, and special thanks to our amazing collaborators at the lab of Adam Reitzel!
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November 25, 2025 at 12:06 PM
4/5 we show that CARDIB and it's RLR partners are indeed crucial for antiviral immunity. Take home message: not every positive BLAST result tell you the function and orthology of a protein in another organism, and, CARDIB rocks!
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November 25, 2025 at 12:06 PM
3/5 we present transcriptomic and functional data from unprecedented number of #Nematostella mutant lines, and "rewildering" experiments where we expose the mutants to native conditions and water full with viruses from the blackish lagoons where Nematostella comes from!
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November 25, 2025 at 12:06 PM
2/5 CARDIB is the best reciprocal BLAST hit to MAVS (aka IPS, VISA and CARDIF) of mammals. Yet, we show it is not an ortholog of MAVS and works in a completely opposite fashion: it inhibits RIG-I-based signaling and antiviral response rather than promoting it!
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November 25, 2025 at 12:06 PM
3/3 this is a co demonstration how adaptation of experimental methods in genomics and cell biology into less conventional model organisms can shed light on evolutionary questions. Kudos to Itamar and to Daria Aleshkina, Adrian Jaimes-Becerra & Matan Levy from our lab who helped him.
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October 7, 2025 at 12:13 PM
2/3 stinging cells, aka cnidocytes, are the cells that define Cnidaria. Their organelles are the ones injecting venom when you are stung by a 🪼 or 🪸. Itamar's work highlights their molecular complexity and how they can be divided epigenetically into distinct populations. >>>
October 7, 2025 at 12:13 PM
Very cool! Congratulations, Luisa!
September 3, 2025 at 6:32 PM
Well, I would say that relying on where a paper was published is still not a good proxy (that's an understatement), for the quality of a paper but far less terrible than thinking that high impact factor equals a "good" journal while low impact factor equals a "bad" journal.
June 21, 2025 at 6:48 PM
2/2 2/2 things that carry "Science" and "Cell" in their titles mostly went up. Everything else? Well, it just crashed and burned. What does it mean? Absolutely nothing. Scientists that continue relying on these archaic metrics should be ashamed of themselves cause they are just lazy SOBs...
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June 21, 2025 at 5:13 PM