@ycluster.bsky.social
I'm excited to share two Haura lab papers out in Cancer Research: we derived a panel of cell lines with resistance to KRAS inhibitors and dissected their mechanisms of resistance by mutliomics linked to drug and CRISPR screens and lots of good ol' validation assays.
aacrjournals.org/cancerres/ar...
aacrjournals.org/cancerres/ar...
RAS-GTP Inhibition Overcomes Acquired Resistance to KRASG12C Inhibitors Mediated by Oncogenic and Wildtype RAS Activation in Non-Small Cell Lung Cancer
Abstract. Small molecule KRASG12C(OFF) inhibitors that bind to the inactive GDP-bound state of KRAS have demonstrated efficacy in patients with KRASG12C mutant tumors, yet responses tend to be transie...
aacrjournals.org
October 31, 2025 at 3:21 AM
I'm excited to share two Haura lab papers out in Cancer Research: we derived a panel of cell lines with resistance to KRAS inhibitors and dissected their mechanisms of resistance by mutliomics linked to drug and CRISPR screens and lots of good ol' validation assays.
aacrjournals.org/cancerres/ar...
aacrjournals.org/cancerres/ar...
well im over here now, just like yall...hi! :)
let me know where all the great science posters are at! smart, snarky takes taken, too
let me know where all the great science posters are at! smart, snarky takes taken, too
November 16, 2024 at 3:25 AM
well im over here now, just like yall...hi! :)
let me know where all the great science posters are at! smart, snarky takes taken, too
let me know where all the great science posters are at! smart, snarky takes taken, too