John Christodouleas
@xristodouleas.bsky.social
Radiation Oncologist at PENN and Elekta Medical Affairs.
t.co/BBFJjqLdMS
GBM Rad Oncs: if 5 fx is proven non-inferior with respect to OS, does it win the day?
As a non-GBM doc, I’m puzzled why in 2025 this hasn’t been already investigated more broadly given the prognosis and prior work from Stanford.
@mrlconsortium.bsky.social
GBM Rad Oncs: if 5 fx is proven non-inferior with respect to OS, does it win the day?
As a non-GBM doc, I’m puzzled why in 2025 this hasn’t been already investigated more broadly given the prognosis and prior work from Stanford.
@mrlconsortium.bsky.social
June 23, 2025 at 2:54 PM
t.co/BBFJjqLdMS
GBM Rad Oncs: if 5 fx is proven non-inferior with respect to OS, does it win the day?
As a non-GBM doc, I’m puzzled why in 2025 this hasn’t been already investigated more broadly given the prognosis and prior work from Stanford.
@mrlconsortium.bsky.social
GBM Rad Oncs: if 5 fx is proven non-inferior with respect to OS, does it win the day?
As a non-GBM doc, I’m puzzled why in 2025 this hasn’t been already investigated more broadly given the prognosis and prior work from Stanford.
@mrlconsortium.bsky.social
@mrlconsortium.bsky.social
Early indication of treatment response in rectal cancer using sequential diffusion-weighted imaging on a 1.5 T MR-linac. user-swndwmf.cld.bz/ESTRO-2025-A.... Study from Tübingen suggests ADC changes during 1st week of chemo-RT might be prognostic of treatment response.
Early indication of treatment response in rectal cancer using sequential diffusion-weighted imaging on a 1.5 T MR-linac. user-swndwmf.cld.bz/ESTRO-2025-A.... Study from Tübingen suggests ADC changes during 1st week of chemo-RT might be prognostic of treatment response.
ESTRO 2025 - Abstract Book
Animated publication
user-swndwmf.cld.bz
April 27, 2025 at 2:20 PM
@mrlconsortium.bsky.social
Early indication of treatment response in rectal cancer using sequential diffusion-weighted imaging on a 1.5 T MR-linac. user-swndwmf.cld.bz/ESTRO-2025-A.... Study from Tübingen suggests ADC changes during 1st week of chemo-RT might be prognostic of treatment response.
Early indication of treatment response in rectal cancer using sequential diffusion-weighted imaging on a 1.5 T MR-linac. user-swndwmf.cld.bz/ESTRO-2025-A.... Study from Tübingen suggests ADC changes during 1st week of chemo-RT might be prognostic of treatment response.
@mrlconsortium.bsky.social Outcomes of patients with liver oligometastases treated with MRI- or cone-beam CT-guided SBRT from MOMENTUM and OligoCare registries:
ESTRO 2025 - Abstract Book
Animated publication
user-swndwmf.cld.bz
April 27, 2025 at 2:19 PM
@mrlconsortium.bsky.social Outcomes of patients with liver oligometastases treated with MRI- or cone-beam CT-guided SBRT from MOMENTUM and OligoCare registries:
@mrlconsortium.bsky.social Feasibility of Therapist-Driven MR-guided adaptive radiotherapy for oligometastatic disease: user-swndwmf.cld.bz/ESTRO-2025-A...
From Princess Margaret Cancer Center. Shows comparable dosimetric outcomes between RTT-led vs. RO-led online adaption for oligo-mets.
From Princess Margaret Cancer Center. Shows comparable dosimetric outcomes between RTT-led vs. RO-led online adaption for oligo-mets.
ESTRO 2025 - Abstract Book
Animated publication
user-swndwmf.cld.bz
April 27, 2025 at 2:17 PM
@mrlconsortium.bsky.social Feasibility of Therapist-Driven MR-guided adaptive radiotherapy for oligometastatic disease: user-swndwmf.cld.bz/ESTRO-2025-A...
From Princess Margaret Cancer Center. Shows comparable dosimetric outcomes between RTT-led vs. RO-led online adaption for oligo-mets.
From Princess Margaret Cancer Center. Shows comparable dosimetric outcomes between RTT-led vs. RO-led online adaption for oligo-mets.
The SPRINT and MOMENTUM studies exemplify Common Sense (Radiation) Oncology. As a field, we must reject traditional Pharma-centric RCT models and adopt methodologies better suited to RadOnc. That means: platform registries, TwiCs, and Bayesian designs.
🎉We’re excited to announce that the first patient has been randomised in the SPRINT study!
The patient was enrolled at Inselspital in Bern under the supervision of PI Professor Hossein Hemmatazad.
Learn more: project.eortc.org/e2-radiate/2...
#E2RADIatE #OligoCare #CancerResearch
The patient was enrolled at Inselspital in Bern under the supervision of PI Professor Hossein Hemmatazad.
Learn more: project.eortc.org/e2-radiate/2...
#E2RADIatE #OligoCare #CancerResearch
April 23, 2025 at 11:19 AM
The SPRINT and MOMENTUM studies exemplify Common Sense (Radiation) Oncology. As a field, we must reject traditional Pharma-centric RCT models and adopt methodologies better suited to RadOnc. That means: platform registries, TwiCs, and Bayesian designs.
More fodder for the bladder filling debate.
Some prostate patients experience urinary urgency during their radiation treatment.
That pressure can cause the prostate to move inferiorly, highlighted here in the video below courtesy of Dr Cem Onal, University of Başkent
#ProgressThroughCollaboration
That pressure can cause the prostate to move inferiorly, highlighted here in the video below courtesy of Dr Cem Onal, University of Başkent
#ProgressThroughCollaboration
April 16, 2025 at 3:20 AM
More fodder for the bladder filling debate.
For muscle-invasive bladder cancer, the Lancet Oncology paper by Zlotta et al is the best comparative effectiveness study of TMT versus RC. How can we use this study to communicate the risks of delayed cystectomy to patients? Peppin A et al provide an answer at GU ASCO 2025:
February 16, 2025 at 6:24 PM
For muscle-invasive bladder cancer, the Lancet Oncology paper by Zlotta et al is the best comparative effectiveness study of TMT versus RC. How can we use this study to communicate the risks of delayed cystectomy to patients? Peppin A et al provide an answer at GU ASCO 2025:
Dan Hyer is a talented communicator. If you have a Unity, don’t miss his presentation on how to optimize use of CMM. If you can’t make it live, a recording will be available afterwards on the Consortium website.
Don't miss out on our first webinar of 2025! Open to all MR-Linac Consortium members.
Member Portal Access: www.mrlconsorium.org
Member Portal Access: www.mrlconsorium.org
February 5, 2025 at 11:45 AM
Dan Hyer is a talented communicator. If you have a Unity, don’t miss his presentation on how to optimize use of CMM. If you can’t make it live, a recording will be available afterwards on the Consortium website.
In a future where we adapt (almost) every fraction—regardless of imaging modality—thoughtful and efficient remote access workflows will be essential. Join us and share your best practices!
Don't miss out on our first webinar of 2025! Open to all MR-Linac Consortium members.
www.mrlconsorium.org
www.mrlconsorium.org
January 6, 2025 at 12:06 PM
In a future where we adapt (almost) every fraction—regardless of imaging modality—thoughtful and efficient remote access workflows will be essential. Join us and share your best practices!
Reposted by John Christodouleas
We are looking for a new consultant colleague at The Royal Marsden Sutton. You too could have the joy of working with @ccparker.bsky.social and many other wonderful people. You might even get to meet @asharpmedonc.bsky.social!
www.jobs.nhs.uk/candidate/jo...
www.jobs.nhs.uk/candidate/jo...
Job Advert
www.jobs.nhs.uk
December 20, 2024 at 6:02 PM
We are looking for a new consultant colleague at The Royal Marsden Sutton. You too could have the joy of working with @ccparker.bsky.social and many other wonderful people. You might even get to meet @asharpmedonc.bsky.social!
www.jobs.nhs.uk/candidate/jo...
www.jobs.nhs.uk/candidate/jo...
Reposted by John Christodouleas
MRI Vs CT Guidance for Stereotactic Body Radiotherapy in #ProstateCancer
MIRAGE trial out on European Urology
Results suggest that MRI-guided SBRT offers long-term benefits in reducing toxic effects by allowing for more aggressive margin reduction in treatment planning.
https://buff.ly/4fA8VmA
MIRAGE trial out on European Urology
Results suggest that MRI-guided SBRT offers long-term benefits in reducing toxic effects by allowing for more aggressive margin reduction in treatment planning.
https://buff.ly/4fA8VmA
November 16, 2024 at 1:58 PM
MRI Vs CT Guidance for Stereotactic Body Radiotherapy in #ProstateCancer
MIRAGE trial out on European Urology
Results suggest that MRI-guided SBRT offers long-term benefits in reducing toxic effects by allowing for more aggressive margin reduction in treatment planning.
https://buff.ly/4fA8VmA
MIRAGE trial out on European Urology
Results suggest that MRI-guided SBRT offers long-term benefits in reducing toxic effects by allowing for more aggressive margin reduction in treatment planning.
https://buff.ly/4fA8VmA