Will Branchett
@wjbranchett.bsky.social
Mucosal immunologist at the Francis Crick Institute, London
A nice discussion here of our work on the early immune response in M. tuberculosis infection and the great recent paper from @bengern.bsky.social et al
First impressions count in #TB. Andrea Cooper @uniofleicester.bsky.social discusses studies by @wjbranchett.bsky.social et al. (rupress.org/jem/article/...) and @bengern.bsky.social et al. (rupress.org/jem/article/...), in Insights: rupress.org/jem/article/...
November 4, 2025 at 3:33 PM
A nice discussion here of our work on the early immune response in M. tuberculosis infection and the great recent paper from @bengern.bsky.social et al
Reposted by Will Branchett
Stetsenko et al. show that TCR clonotypes from individuals latently infected w/ M. #tuberculosis demonstrate dominant but not exclusive recognition of infected #macrophages, specificity for type VII secretion system substrates, & expression of canonical effector programs rupress.org/jem/article/...
September 24, 2025 at 4:50 PM
Stetsenko et al. show that TCR clonotypes from individuals latently infected w/ M. #tuberculosis demonstrate dominant but not exclusive recognition of infected #macrophages, specificity for type VII secretion system substrates, & expression of canonical effector programs rupress.org/jem/article/...
Pleased to see this out now in @jem.org 🔬
We characterise the early immune response during M. tuberculosis infection in mouse models and demonstrate a detrimental role for type I interferon activated neutrophils in TB lesions. Thanks to all involved @crick.ac.uk and i3S, Porto.
We characterise the early immune response during M. tuberculosis infection in mouse models and demonstrate a detrimental role for type I interferon activated neutrophils in TB lesions. Thanks to all involved @crick.ac.uk and i3S, Porto.
William J. Branchett, Anne O’Garra @crick.ac.uk et al. reveal that type I signaling early during M. #tuberculosis infection favors #neutrophil swarming and limits CD4+ T cell–#macrophage interactions in #TB lesions, impeding TB disease control. rupress.org/jem/article/...
September 24, 2025 at 6:10 AM
Pleased to see this out now in @jem.org 🔬
We characterise the early immune response during M. tuberculosis infection in mouse models and demonstrate a detrimental role for type I interferon activated neutrophils in TB lesions. Thanks to all involved @crick.ac.uk and i3S, Porto.
We characterise the early immune response during M. tuberculosis infection in mouse models and demonstrate a detrimental role for type I interferon activated neutrophils in TB lesions. Thanks to all involved @crick.ac.uk and i3S, Porto.
Great day out talking all things infection at #LINEsymposium2025 today. Thanks for having me!
We are heading straight into session 3 of our selected talks. @wjbranchett.bsky.social @crick.ac.uk is up first, focussing on M. tuberculosis infection. #LINEsymposium2025
June 9, 2025 at 6:26 PM
Great day out talking all things infection at #LINEsymposium2025 today. Thanks for having me!
Looking forward to presenting our work on early mechanisms of TB susceptibility at the @londoninfectionecr.bsky.social Symposium in June 🦠🔬
We can see our ECR-focused LINE symposium already on the horizon (9th of June) @crick.ac.uk. shorturl.at/MyWNl 🥳
You can submit your abstracts (talk or poster) until the EXTENDED DEADLINE on the 12th of May here: shorturl.at/7KuXL
Free registration shorturl.at/wLyWY
We're excited to see you there!
You can submit your abstracts (talk or poster) until the EXTENDED DEADLINE on the 12th of May here: shorturl.at/7KuXL
Free registration shorturl.at/wLyWY
We're excited to see you there!
May 26, 2025 at 6:28 PM
Looking forward to presenting our work on early mechanisms of TB susceptibility at the @londoninfectionecr.bsky.social Symposium in June 🦠🔬