William Garland
willgarland.bsky.social
William Garland
@willgarland.bsky.social
RNA decay, RNA sorting, transcriptional regulation
Aarhus University, Denmark 🇩🇰
Registration and abstract submission is open for the 10th annual Danish RNA Society meeting 🇩🇰 - this year in Aarhus!
Deadline is October 1st
danish-rna-society.nemtilmeld.dk/8/
September 10, 2025 at 6:15 PM
Happy to share our latest collaboration with the Cusack and Kadlec groups—now published in @natsmb.nature.com
Combining cryo-EM, structure-guided mutants & proximity labeling, we show how PHAX, CBC, CRM1 & Ran‑GTP assemble the snRNA export complex
Article: rdcu.be/euC4U
News & Views: rdcu.be/euC5l
July 3, 2025 at 10:25 AM
We put together a spotlight for @cp-cellchembiol.bsky.social highlighting the recent work from @baluapuri.bsky.social and @adelmanlab.bsky.social published in @cp-cell.bsky.social.

Here they show how a breakdown in nuclear RNA regulation sends ripples of stress throughout the cell.
June 19, 2025 at 6:21 PM
📢 Latest publication from the lab! We explore how cells manage the excess pA− RNAs generated by pervasive transcription. While the NEXT complex usually takes charge, in its absence, a network of tailing enzymes, export factors, and exonucleases steps in to modify and degrade these RNAs.
December 13, 2024 at 8:25 AM
Latest from the lab, finally out in Molecular Cell. Here we show a physical and functional link between the Microprocessor and a variant NEXT complex. Together, these complexes degrade the 5' flanks of pre-miRNAs and other stem-loop-containing RNAs.
doi.org/10.1016/j.mo...
November 8, 2024 at 7:22 AM
We put together a Molecular Cell preview for the latest papers from Wojtek Galej and Stefanie Jonas uncovering fascinating new details about the Integrator complex.

Preview here:
t.co/XGMwJwBOZa
Articles here:
t.co/9lx1z3bvE6
t.co/k0EqO54gXB
July 12, 2024 at 8:02 AM
Representing MBG🇩🇰 at #RNA24
We actually got some sun out of Edinburgh
June 2, 2024 at 9:49 AM
Lovely bonus from #RNA24 was winning a (very generous) poster prize ✌️
June 2, 2024 at 9:47 AM
Great way to start the year! Nice collaboration with the Cusack and Kadlec teams dissecting the interactions of RNA effectors with the cap-binding complex and ARS2.
www.cell.com/cell-reports...
January 4, 2024 at 7:57 PM